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Sotylize Bottle — prescription drug image

Sotylize

Sotylize 250ML of 5MG/ML

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What is Sotylize?

Sotylize is a group III antiarrhythmic drug used to treat patients diagnosed with atrial fibrillation. There is not a Sotylize generic drug currently available on the market. Sotylize costs around $282 for a supply of 144 of 5 mg/ml solution. You can use our Rx.com Sotylize savings card to save significantly on the retail price at participating pharmacies near you.

Prescription savings · · · ·

What is Sotylize ?

Sotylize is a group III antiarrhythmic drug used to treat patients diagnosed with atrial fibrillation. There is not a Sotylize generic drug currently available on the market. Sotylize costs around $282 for a supply of 144 of 5 mg/ml solution. You can use our Rx.com Sotylize savings card to save significantly on the retail price at participating pharmacies near you.
  • Rapid weight gain, swelling in your hands, feet, or ankles
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain, cough, trouble breathing
  • Dry mouth, increased thirst, muscle cramps, nausea or vomiting
  • Fast, slow, or irregular heartbeat
  • Fainting, dizziness, lightheadedness
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Tell your doctor if you are pregnant, or if you have kidney disease, diabetes, heart disease, angina, low blood pressure, lung or breathing problems, thyroid problems, or a history of heart attack.
  • Do not breastfeed during treatment with Betapace®.
  • This medicine may cause the following problems: Increased risk of heart failureHeart rhythm problem, including QT prolongationChanges in blood sugar levels
  • This medicine may cover up signs of low blood sugar in patients with diabetes or who are fasting (including surgery, not eating regularly, vomiting).
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • This medicine may make you dizzy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Stand up slowly if you feel dizzy or lightheaded.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
What is Sotylize (sotalol) used for?
Sotylize is a brand of sotalol hydrochloride, an antiarrhythmic. It is FDA-approved to treat documented life-threatening ventricular arrhythmias (such as ventricular tachycardia) and to maintain normal sinus rhythm in people with symptomatic atrial fibrillation or atrial flutter who are currently in normal rhythm. Because it is an oral liquid, it is useful for patients who cannot swallow tablets, including some children and older adults.
Why does Sotylize have to be started in a hospital?
Sotylize can prolong the QT interval and, in rare cases, trigger a dangerous heart rhythm called torsades de pointes. Because of this, its FDA Boxed Warning requires that it be started or re-started in a facility with continuous ECG monitoring and the ability to handle a cardiac emergency. This lets the care team watch your heart rhythm and QT interval and adjust the dose safely.
Is Sotylize the same as sotalol tablets?
Sotylize contains the same active ingredient, sotalol hydrochloride, as tablet brands like Betapace, Betapace AF, and Sorine (and low-cost generic sotalol tablets). The main difference is the form: Sotylize is an oral solution (liquid) rather than a tablet, which makes it easier to take for people who cannot swallow pills. Dosing still has to be individualized, so do not switch forms without your doctor's guidance.
What are the most serious side effects of Sotylize?
The most serious risk is a life-threatening irregular heartbeat (torsades de pointes) tied to QT-interval prolongation, which is why it carries a Boxed Warning and requires in-hospital monitoring at the start. Other serious effects can include a very slow heartbeat, low blood pressure, worsening heart failure, and bronchospasm (airway narrowing). It can also hide the warning signs of low blood sugar in people with diabetes. Do not stop it suddenly, and report any fainting, dizziness, or a racing or very slow heartbeat to your doctor right away.
Is there a generic version of Sotylize oral solution?
Not currently. The FDA has not approved a substitutable generic of the Sotylize (sotalol hydrochloride) oral solution, so the liquid form is brand-only right now. Sotalol is available as low-cost generic tablets, but tablets and the oral solution are not the same form, so do not switch between them without your doctor's guidance. Enter your ZIP above to compare today's prices, and ask your pharmacist whether a generic tablet is appropriate for you.
How much does Sotylize cost without insurance?
The price of Sotylize without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Sotylize?
Common side effects of Sotylize may include: Rapid weight gain, swelling in your hands, feet, or ankles, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Chest pain, cough, trouble breathing, Dry mouth, increased thirst, muscle cramps, nausea or vomiting, Fast, slow, or irregular heartbeat. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Sotylize?
Generic versions may be available for Sotylize. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Sotylize on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Sotylize?
The cheapest pharmacy for Sotylize depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Sotylize near you.

Sotylize Coupons & Prices

Sotylize 250ML of 5MG/ML

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Sotylize Bottle — prescription drug image
Prescription
Sotylize 250ml of 5mg/ml (0.24)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a Sotylize coupon? Sotylize is the brand-name oral liquid form of sotalol hydrochloride, a Class III antiarrhythmic prescribed to treat life-threatening ventricular arrhythmias and to keep the heart in normal rhythm in people with atrial fibrillation or atrial flutter. Because it is a liquid, it is often used for patients who cannot swallow tablets, including some children and older adults. Use the free Rx.com discount coupon at the pharmacy counter to lower the cash price of your prescription. Enter your ZIP above to see today's price at pharmacies near you.

What is Sotylize and how does it work?

Sotylize is a brand of sotalol hydrochloride, an antiarrhythmic medicine that belongs to the Class III (potassium channel blocker) group and also has non-selective beta-blocker activity. In plain terms, it works in two ways at once: it slows electrical signals that can trigger a dangerously fast or irregular heartbeat, and it eases the workload on the heart the way a beta-blocker does. This helps restore and maintain a steadier heart rhythm.

Sotylize is FDA-approved to treat documented life-threatening ventricular arrhythmias, such as ventricular tachycardia, and to maintain normal sinus rhythm (delay the return of the abnormal rhythm) in people with symptomatic atrial fibrillation or atrial flutter who are currently in normal rhythm. What sets Sotylize apart is that it is an oral solution rather than a tablet, which makes it useful for pediatric patients, older adults, and anyone who has trouble swallowing pills. Sotalol is also used to treat certain arrhythmias in children.

Sotylize cost: manufacturer savings card vs. Rx.com cash coupon

The manufacturer of Sotylize runs an official savings program you can find on the brand's own website (Sotylize.com). Manufacturer copay cards like these are generally limited to people with commercial (private) insurance, and the exact terms, eligibility, and expiration vary, so read the fine print. They typically cannot be used if you are uninsured or covered by a government program such as Medicare, Medicaid, or TRICARE.

That is where the free Rx.com cash coupon comes in. It is a discount on the cash price, so it can help when you are uninsured, when you have Medicare, or when a manufacturer card is declined at the counter. You do not use it together with insurance; you pick whichever price is lower. It helps to understand the generic picture: sotalol hydrochloride tablets are available as low-cost generics, and there are also brand tablets such as Betapace, Betapace AF, and Sorine. However, there is currently no FDA-approved generic of the Sotylize oral solution — the liquid form is brand-only — so if you specifically need the liquid, compare the cash coupon price against any manufacturer or insurance price. Ask your prescriber or pharmacist whether a generic tablet is an option for you. Enter your ZIP above to see today's price on Sotylize at pharmacies near you.

Sotylize alternatives and related medications

Sotylize is one of several sotalol products and antiarrhythmic options. Related medications include:

  • Sotalol — the generic active ingredient, available as low-cost generic tablets; the oral-solution form is currently brand-only (Sotylize).
  • Betapace — a brand of sotalol tablets.
  • Sorine — another brand of sotalol tablets.
  • Amiodarone — a different antiarrhythmic sometimes used for similar rhythm problems.
  • Dofetilide — a Class III antiarrhythmic used to maintain normal rhythm in atrial fibrillation.

These medicines are not interchangeable, and each has its own dosing, monitoring, and safety profile. Only your cardiologist can decide which is right for you. This information is educational and is not medical advice.

Important safety information

Sotylize carries an FDA Boxed Warning: it can cause a life-threatening irregular heartbeat called torsades de pointes, linked to prolonging of the QT interval on an ECG. For this reason, treatment must be started or re-started in a hospital or facility with continuous heart (ECG) monitoring and the ability to treat a cardiac emergency. The dose is individualized to your kidney function (creatinine clearance) and QT interval, and your care team may reduce or stop the drug if your QTc reaches 500 msec or more. Do not stop Sotylize suddenly on your own.

Other risks include a slow heartbeat (bradycardia), low blood pressure, worsening heart failure, narrowing of the airways (bronchospasm), and masking of low-blood-sugar symptoms in people with diabetes. Sotylize should not be used by people with certain conditions, such as very slow heart rate, some types of heart block without a pacemaker, congenital or acquired long QT syndrome, cardiogenic shock, uncontrolled heart failure, asthma or related bronchospasm, sick sinus syndrome, low potassium, severe kidney impairment (for the AFib/atrial flutter use), or a known allergy to sotalol. Tell your doctor about all your health conditions and medicines. This is a brief summary, not a complete list; talk with your prescriber or pharmacist and follow their guidance.

Sources & accuracy

This Sotylize information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Sotylize on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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