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Tobramycin-Dexamethasone Bottle — prescription drug image

Tobramycin-Dexamethasone

Tobramycin-dexAMETHasone 5ML of 0.3-0.1%

Prescriptions & Refills
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What is Tobramycin-Dexamethasone?

Tobramycin-Dexamethasone is used to treat eye infections and relieve eye irritations. The average Tobramycin-Dexamethasone retail cost is approximately $105 for a supply of 5, 0.3-0.1% suspension. However, you can significantly reduce the Tobramycin-Dexamethasone price by using our free Singlecare coupon card at participating local pharmacies.

Prescription savings · · · ·

What is Tobramycin-Dexamethasone ?

Tobramycin-Dexamethasone is used to treat eye infections and relieve eye irritations. The average Tobramycin-Dexamethasone retail cost is approximately $105 for a supply of 5, 0.3-0.1% suspension. However, you can significantly reduce the Tobramycin-Dexamethasone price by using our free Singlecare coupon card at participating local pharmacies.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Severe eye irritation that was not there before using this medicine
  • Vision changes
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Make sure your doctor knows if you have glaucoma, cataracts, or any other eye condition before taking this medicine.
  • If you are pregnant or breastfeeding, talk to your doctor before using this medicine.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
What is tobramycin and dexamethasone eye drops used for?
They are FDA-approved for steroid-responsive inflammatory eye conditions where a corticosteroid is indicated and a superficial bacterial eye infection, or the risk of one, is also present. The label covers inflammation of the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the eye; chronic anterior uveitis; and corneal injury from chemical, radiation, or thermal burns or from a foreign body. It is not injected into the eye. Your eye doctor decides whether it fits your condition.
How long can you use tobramycin and dexamethasone eye drops?
Use it only for as long as your prescriber tells you to. Prolonged corticosteroid use in the eye can raise intraocular pressure and lead to glaucoma with optic nerve damage, vision changes, and cataract formation, so the label says eye pressure should be routinely monitored, while noting that monitoring can be difficult in children and in uncooperative patients. Do not extend a course or restart leftover medicine on your own.
Is tobramycin and dexamethasone the same as TobraDex?
Essentially, for the eye drops. TobraDex is the brand name for tobramycin and dexamethasone ophthalmic, and FDA-approved generics of the 0.3%/0.1% ophthalmic suspension are available from several manufacturers. The ophthalmic ointment and TobraDex ST are marketed as brand-name products. TobraDex ST also contains dexamethasone 0.05% rather than 0.1%, so it is a different strength, not a like-for-like swap. Whether a pharmacy can substitute a generic for a brand depends on state law, the FDA therapeutic-equivalence rating, and your prescriber's instructions.
What are the side effects of tobramycin and dexamethasone eye drops?
Local reactions can include lid itching and swelling and redness of the conjunctiva, which may reflect aminoglycoside sensitivity that can cross-react with other aminoglycosides. More serious risks come with longer use: raised eye pressure and possible glaucoma with optic nerve damage, reduced visual sharpness or visual field defects, and posterior subcapsular cataract formation. The steroid can also mask or worsen an existing infection, delay healing, and promote a secondary bacterial or fungal infection. Tell your eye doctor about any eye pain, vision change, or symptoms that are not improving.
Do you have to shake tobramycin and dexamethasone eye drops?
Yes. The drops are a suspension, and the label directs you to shake the bottle well before each use so the medicine is evenly mixed. Also do not wear contact lenses while you are being treated; the suspension contains benzalkonium chloride, a preservative that can be absorbed by soft lenses.
How much does Tobramycin-Dexamethasone cost without insurance?
The price of Tobramycin-Dexamethasone without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 57% off retail prices with a free Rx.com coupon.
What are the common side effects of Tobramycin-Dexamethasone?
Common side effects of Tobramycin-Dexamethasone may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Severe eye irritation that was not there before using this medicine, Vision changes. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Tobramycin-Dexamethasone?
Generic versions may be available for Tobramycin-Dexamethasone. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Tobramycin-Dexamethasone on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Tobramycin-Dexamethasone?
The cheapest pharmacy for Tobramycin-Dexamethasone depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Tobramycin-Dexamethasone near you.

Tobramycin-Dexamethasone Coupons & Prices

Tobramycin-dexAMETHasone 5ML of 0.3-0.1%

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Tobramycin-Dexamethasone Bottle — prescription drug image
Prescription
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A tobramycin and dexamethasone coupon from Rx.com can lower what you pay at the pharmacy counter for this generic eye medication, which combines the antibiotic tobramycin with the steroid dexamethasone. The generic is the equivalent of TobraDex ophthalmic suspension, the eye drops you shake before each use. The combination is also made as an ophthalmic ointment and as TobraDex ST, but those forms are sold under the brand name, so a generic price applies to the drops. Cash prices for the same prescription can differ a lot from one pharmacy to the next, even between stores a few miles apart, so it pays to compare. Enter your ZIP code above to see today's price at pharmacies near you.

What is tobramycin and dexamethasone, and how does it work?

Tobramycin and dexamethasone ophthalmic is a two-in-one eye medicine. Tobramycin 0.3% is an aminoglycoside antibiotic that treats or helps prevent bacterial infection on the surface of the eye. Dexamethasone is a corticosteroid that calms swelling, redness, and irritation. The standard suspension contains dexamethasone 0.1%; the ST formulation contains 0.05%. The combination is made as an eye drop suspension and as an ophthalmic ointment, and generic versions are approved as the suspension.

The FDA-approved use is for steroid-responsive inflammatory eye conditions where a corticosteroid is called for and where a superficial bacterial eye infection, or the risk of one, also exists. Per the label, that includes inflammation of the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the eye; chronic anterior uveitis; and corneal injury from chemical, radiation, or thermal burns or from a foreign body. Only your eye doctor can decide whether this combination is right for your situation. This product is never injected into the eye.

What tobramycin and dexamethasone costs without insurance

There is no manufacturer savings card for this generic. If you are paying cash, the number that matters is the price at the specific pharmacy you walk into, and those prices are set store by store rather than nationally. The same bottle can carry very different cash prices at a chain, a grocery-store pharmacy, and an independent across town, which is exactly why comparing before you fill is worth the two minutes.

Rx.com compares prices across more than 60,000 participating pharmacies and gives you a free coupon to show at the counter. Enter your ZIP code above to see today's price for the drops near you. The coupon is for cash-paying customers and cannot be combined with insurance, though it is always worth checking both ways, since sometimes the coupon price beats your copay and sometimes it doesn't.

TobraDex and other eye medication alternatives

TobraDex is the brand name for this combination, and the FDA-approved generic covers the ophthalmic suspension. The ophthalmic ointment and TobraDex ST (which uses dexamethasone 0.05%) are marketed as brand-name products, so ask your pharmacist what is actually stockable for the form you were prescribed. Whether a pharmacist can hand you a generic in place of a brand depends on your state's substitution law, the FDA therapeutic-equivalence rating, and what your prescriber wrote, so it is a question worth asking at the counter rather than assuming.

Other prescription eye products your doctor may consider, depending on whether you need an antibiotic, a steroid, or both:

These are not interchangeable. Adding or removing a steroid changes the risks, so this is a conversation for your prescriber, not a switch to make on your own.

Safety information to know

This medicine has no boxed warning, but it is not for injection into the eye. It should not be used if you have epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, other viral diseases of the cornea and conjunctiva, mycobacterial eye infection, or fungal eye disease, or if you are allergic to any ingredient. Steroids can mask or worsen an existing infection, slow healing, and encourage a secondary bacterial or fungal infection; a corneal ulcer that will not clear should raise suspicion of fungal invasion. In diseases that thin the cornea or sclera, steroid use can lead to perforation.

Prolonged corticosteroid use in the eye can raise eye pressure and lead to glaucoma with optic nerve damage, loss of visual sharpness or visual field, and cataract formation behind the lens. Because of this, the label says eye pressure should be routinely monitored, while noting that monitoring can be difficult in children and in uncooperative patients. Aminoglycoside sensitivity can cause lid itching and swelling and conjunctival redness, and may cross-react with other aminoglycosides. Do not wear contact lenses during treatment; the suspension contains benzalkonium chloride 0.01% as a preservative. Shake the suspension well before each use. Safety and effectiveness have not been established in children under 2 years. This is general information, not medical advice, so follow your own provider's instructions.

Sources & accuracy

This Tobramycin-Dexamethasone information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Tobramycin-Dexamethasone on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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