Trokendi Xr
Trokendi XR 100MG
What is Trokendi Xr?
Trokendi XR is used in the treatment and prevention of seizures. Topiramate is the generic version of Trokendi XR. The average Trokendi XR cost is about $313 for a supply of 30, 25 mg capsules. However, you can significantly reduce the Trokendi XR price by using our free Singlecare coupon card at participating local pharmacies.Side Effects
- Changes in vision, eye pain
- Fever, decreased sweating
- Confusion, problems with walking, clumsiness, dizziness, trouble talking, concentrating, or remembering
Warnings
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, glaucoma, lung or breathing problems, bone problems (including osteoporosis, osteomalacia, osteopenia), or a history of depression or mood disorders. Tell your doctor if you are on a ketogenic diet (high in fat and low in carbohydrates).
- This medicine may cause the following problems:Eye pain or vision changes, including glaucomaChanges in body temperatureChanges in mood or behavior, including thoughts of suicideMetabolic acidosis (too much acid in the blood)Decreased bone densitySlow growth in childrenSerious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysisKidney stones
- This medicine may make you dizzy, drowsy, or tired. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
Prescription savings · · · ·
What is Trokendi Xr ?
Trokendi XR is used in the treatment and prevention of seizures. Topiramate is the generic version of Trokendi XR. The average Trokendi XR cost is about $313 for a supply of 30, 25 mg capsules. However, you can significantly reduce the Trokendi XR price by using our free Singlecare coupon card at participating local pharmacies.- Changes in vision, eye pain
- Fever, decreased sweating
- Confusion, problems with walking, clumsiness, dizziness, trouble talking, concentrating, or remembering
- Numbness, tingling, or burning pain in your hands, arms, legs, or feet
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
- Bloody or cloudy urine, painful urination, sudden lower back or stomach pain
- Bone fractures, pain, tenderness, or aching, pain in the back, ribs, arms, or legs, decrease in height
- Slow growth in children
- Unusual drowsiness, tiredness, or weakness
- Feeling agitated, depressed, nervous, or irritable, thoughts of hurting yourself or others, unusual mood or behavior
- Rapid, deep breathing, fast or uneven heartbeat
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, glaucoma, lung or breathing problems, bone problems (including osteoporosis, osteomalacia, osteopenia), or a history of depression or mood disorders. Tell your doctor if you are on a ketogenic diet (high in fat and low in carbohydrates).
- This medicine may cause the following problems:Eye pain or vision changes, including glaucomaChanges in body temperatureChanges in mood or behavior, including thoughts of suicideMetabolic acidosis (too much acid in the blood)Decreased bone densitySlow growth in childrenSerious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysisKidney stones
- This medicine may make you dizzy, drowsy, or tired. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Vomiting, unusual drowsiness, tiredness, or weakness
Trokendi Xr Coupons & Prices
Trokendi XR 100MG
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Looking for a Trokendi XR coupon? Trokendi XR (topiramate extended-release capsules) is a brand-name, once-daily anticonvulsant also prescribed to help prevent migraines, and because a generic version of the extended-release capsule is available, patients often have more than one way to lower the cost — a manufacturer savings card for those with commercial insurance, or the Rx.com cash coupon, which works whether or not you have insurance, including on Medicare or if a savings card is declined at the register; enter your ZIP above to see today's price.
What Is Trokendi XR and How Does It Work?
Trokendi XR is a brand-name, once-daily extended-release capsule form of topiramate, a sulfamate-substituted monosaccharide classified as an anticonvulsant (antiepileptic drug, or AED). Its mechanism is thought to involve several actions together, including blocking sodium channels, enhancing the activity of the calming neurotransmitter GABA, and inhibiting carbonic anhydrase.
The FDA has approved Trokendi XR as initial monotherapy for partial-onset or primary generalized tonic-clonic seizures in patients 6 and older; as add-on (adjunctive) therapy for partial-onset seizures, primary generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome in patients 6 and older; and for the preventive treatment of migraine in patients 12 and older. The capsule must be swallowed whole — it should not be chewed, crushed, or have its contents sprinkled on food except as specifically directed on the label for patients who cannot swallow capsules.
Manufacturer Savings Card vs. the Rx.com Cash Coupon
Trokendi XR's manufacturer offers an official co-pay savings program (details are available directly at the manufacturer's site, trokendixr.com). Programs like this are generally limited to patients with commercial (private) insurance, and terms, eligibility, and caps can change, so it's worth confirming current details before you count on it.
The Rx.com cash coupon is a different option that works regardless of insurance status — useful if you're uninsured, on Medicare (which typically can't use manufacturer copay cards), or if the manufacturer card is declined at the pharmacy counter. Because generic topiramate extended-release capsules are also available, asking your pharmacist about the generic is usually the biggest lever for lowering your out-of-pocket cost. Prices vary by pharmacy and location, so enter your ZIP above to compare today's price near you.
Trokendi XR vs. Topamax vs. Qudexy XR: What's the Difference?
Trokendi XR, Topamax, and Qudexy XR all contain the same active ingredient, topiramate, but they are not the same product. Trokendi XR is an extended-release capsule taken once daily. Topamax is the original immediate-release formulation, typically taken twice daily. Qudexy XR is a different once-daily extended-release brand. Because they release the drug into the body differently, these products are not interchangeable or substitutable for one another — they are not AB-rated to each other — and switching between them should only be done under a doctor's guidance.
A generic version of topiramate extended-release capsules is also available and may offer savings over the brand; ask your pharmacist whether the generic topiramate is right for your prescription.
Safety Information
Trokendi XR does not carry an FDA boxed warning, but its label includes several important warnings you should discuss with your doctor. It has been linked to an increased risk of oral clefts in babies when taken during the first trimester of pregnancy, so it should generally be avoided in pregnancy unless the benefits outweigh the risks. It can also cause acute myopia with secondary angle-closure glaucoma, a condition that can cause permanent vision loss if not treated promptly — seek medical care immediately for sudden eye pain or vision changes. Other warnings include decreased sweating and a risk of overheating or dehydration (oligohidrosis/hyperthermia), especially in children; metabolic acidosis; an increased risk of suicidal thoughts or behavior, a warning shared by anticonvulsant medications as a class; and cognitive effects such as confusion, slowed thinking, or speech and language problems. The label also advises avoiding alcohol within 6 hours before or after taking a dose.
This is not a complete list of safety information. Talk to your doctor or pharmacist about your full medical history and the medication guide before starting Trokendi XR.
This Trokendi Xr information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Trokendi Xr on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.