Xulane
Xulane 3 Patch Weekly
What is Xulane?
Xulane is a skin patch used as a birth control by women to prevent pregnancy. Ethinyl Estradiol-norelgestromin is the generic version of Xulane. Xulane costs around $142 for a supply of 3, 150 mcg/35 mcg patches, but luckily there are ways to save money. You can use our Rx.com Xulane savings caXulane is a prescription birth control patch used to help prevent pregnancy in women of reproductive age. The patch delivers a combination of estrogen and progestin hormones through the skin to prevent ovulation and reduce the likelihood of pregnancy. Learn about Xulane uses, effectiveness, dosage, side effects, cost, and contraceptive options available through Rx.com.rd to save significantly on the retail price at participating pharmacies near you.
Side Effects
- Sudden or severe headache, or problems with vision, speech, or walking
- Sudden and severe stomach pain, nausea, vomiting, lightheadedness
- Unusual or unexpected vaginal bleeding
Warnings
- This medicine will not protect you from getting HIV/AIDS or other sexually transmitted diseases.
- This medicine may not work as well in women who weigh 198 pounds (90 kilograms) or more.
- If you think you have become pregnant while using this medicine, tell your doctor right away.
- Tell your doctor if you are breastfeeding or if you recently had a baby. Tell your doctor if you have kidney disease, epilepsy, diabetes, high cholesterol levels, high blood pressure, gallbladder disease, migraine headaches, irregular monthly periods, or a history of depression, or chloasma gravidarum (skin discoloration during pregnancy). Tell your doctor if you are having a surgery that requires inactivity for a long time or if you smoke.
- This medicine may cause the following problems:Increased risk of heart attack, stroke, or blood clotsLiver problems (including liver cancers or tumors)High blood pressureGallbladder diseaseHigh cholesterol in the bloodPossible risk of breast or cervical cancer
Prescription savings · · · ·
What is Xulane ?
Xulane is a skin patch used as a birth control by women to prevent pregnancy. Ethinyl Estradiol-norelgestromin is the generic version of Xulane. Xulane costs around $142 for a supply of 3, 150 mcg/35 mcg patches, but luckily there are ways to save money. You can use our Rx.com Xulane savings caXulane is a prescription birth control patch used to help prevent pregnancy in women of reproductive age. The patch delivers a combination of estrogen and progestin hormones through the skin to prevent ovulation and reduce the likelihood of pregnancy. Learn about Xulane uses, effectiveness, dosage, side effects, cost, and contraceptive options available through Rx.com.rd to save significantly on the retail price at participating pharmacies near you.
- Sudden or severe headache, or problems with vision, speech, or walking
- Sudden and severe stomach pain, nausea, vomiting, lightheadedness
- Unusual or unexpected vaginal bleeding
- Numbness or weakness in your arm or leg, or on one side of your body
- Irregular, late, or missed menstrual period
- Dark urine or pale stools, loss of appetite, yellow skin or eyes
- Chest pain or tightness, trouble breathing, coughing up blood
- Breast lumps, tenderness, pain, swelling, or discharge
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Pain in your lower leg (calf)
- Rapid weight gain, swelling in your hands, ankles, or feet
- This medicine will not protect you from getting HIV/AIDS or other sexually transmitted diseases.
- This medicine may not work as well in women who weigh 198 pounds (90 kilograms) or more.
- If you think you have become pregnant while using this medicine, tell your doctor right away.
- Tell your doctor if you are breastfeeding or if you recently had a baby. Tell your doctor if you have kidney disease, epilepsy, diabetes, high cholesterol levels, high blood pressure, gallbladder disease, migraine headaches, irregular monthly periods, or a history of depression, or chloasma gravidarum (skin discoloration during pregnancy). Tell your doctor if you are having a surgery that requires inactivity for a long time or if you smoke.
- This medicine may cause the following problems:Increased risk of heart attack, stroke, or blood clotsLiver problems (including liver cancers or tumors)High blood pressureGallbladder diseaseHigh cholesterol in the bloodPossible risk of breast or cervical cancer
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. You may need to stop using this medicine for a few weeks before and after surgery because of the risk of blood clots.
- Unusual or unexpected vaginal bleeding
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Xulane Coupons & Prices
Xulane 3 Patch Weekly
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Looking for a Xulane coupon? Xulane is the weekly birth-control patch that delivers norelgestromin and ethinyl estradiol through the skin, and it is available as a lower-cost generic. With an Rx.com cash coupon you can compare today's pharmacy prices near you and pay the discounted cash price even if you are uninsured, on Medicare, or your insurance does not cover it. Enter your ZIP above to see today's price at pharmacies in your area.
What is Xulane and how does the patch work?
Xulane is a combined hormonal contraceptive skin patch that contains two hormones, norelgestromin (a progestin) and ethinyl estradiol (an estrogen). Each patch releases about 150 mcg of norelgestromin and 35 mcg of ethinyl estradiol per day to help prevent pregnancy. It is FDA-approved to prevent pregnancy in women of reproductive potential with a body mass index (BMI) under 30 kg/m2 who choose a patch as their method of birth control.
You wear one patch per week for three weeks in a row, then have one patch-free week (when your period usually comes), for a four-week cycle. Xulane is a generic equivalent of the original Ortho Evra patch, which has been discontinued. It is sometimes used off-label to help manage or regulate menstrual cycles, but it is not FDA-approved for those purposes. Xulane does not protect against HIV or other sexually transmitted infections.
Xulane cost: manufacturer savings card vs. Rx.com cash coupon
The maker of Xulane runs an official manufacturer savings program, described on the manufacturer's Xulane website. Manufacturer copay cards like this are generally limited to people with commercial (private) insurance, and the terms, eligibility, and any expiration can change, so check the program's current details before you rely on it. These cards typically cannot be used if you have no insurance or if you are covered by a government program such as Medicare or Medicaid.
An Rx.com cash coupon works differently: it is a cash-price discount you can use whether you are uninsured, covered by Medicare or Medicaid, or simply told the manufacturer card was declined. Because Xulane is itself the generic version of the discontinued Ortho Evra, choosing the generic patch is the single biggest lever for lowering your cost. Prices vary by pharmacy and change over time, so enter your ZIP above to see today's price near you and bring the coupon to the pharmacy counter.
Xulane alternatives and how they compare
Xulane is one of several combined hormonal birth-control options, and the right one depends on your health history and how you prefer to take it. Other patch and non-pill choices include Twirla, another weekly contraceptive patch, and NuvaRing, a monthly vaginal ring. If you prefer a daily pill, common combined oral contraceptives include Sprintec, Junel Fe, and Ortho Tri-Cyclen.
All of these use estrogen plus a progestin, but they differ in the specific hormones, dosing schedule, and how they are used. Your provider can help you weigh effectiveness, side effects, and your personal risk factors. This is general information, not medical advice, so talk with your doctor or pharmacist about which method fits you best.
Xulane safety and important warnings
Xulane carries an FDA boxed warning. Cigarette smoking raises the risk of serious cardiovascular events with combined hormonal contraceptives, and Xulane should not be used by women over 35 who smoke. The boxed warning also states that Xulane is contraindicated in women with a BMI of 30 kg/m2 or higher, who may have a higher risk of venous blood clots. Because the patch can expose users to roughly 60% more total estrogen than a typical 35 mcg estrogen pill, there is added concern for venous thromboembolism (blood clots), stroke, and heart attack.
Xulane is contraindicated in people with a BMI of 30 kg/m2 or higher, in those at high risk of arterial or venous blood clots, and in those with breast or other estrogen-sensitive cancers, liver disease or tumors, undiagnosed abnormal vaginal bleeding, or a known or suspected pregnancy. This is a summary and not a complete list. Tell your doctor about your full medical history, and seek care right away for warning signs such as chest pain, sudden shortness of breath, severe leg pain or swelling, or a sudden severe headache. Always follow your provider's guidance.
This Xulane information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Xulane on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.