Black Friday Semaglutide Deal 2026: $495 for 6 Months
Now through December 1, 2026, Rx.com's Black Friday sale gives you 6 months of compounded semaglutide for the price of 3. Here is what it costs, what you get, and the questions to ask before you buy.
Now through Tuesday, December 1, 2026, at 11:59 pm Central, Rx.com's Black Friday sale gives you 6 months of compounded semaglutide for the price of 3: $495 for 6 months, paid once up front, about $2.71 a day. The price is the same at every dose, and there is no code to enter.
- No code: take the short eligibility quiz and the price is applied at checkout automatically.
- Dates: now through December 1, 2026, 11:59 pm Central. Regular prices apply after that.
- 6-month plan: $495 up front (about $82.50 a month), down from $875. You save $380.
- 1-month plan: $139 during the sale, down from $175.
- Includes the provider review, medication, supplies and free express shipping.
- Compounded semaglutide is not FDA-approved.
How the Black Friday sale works
Rx.com's Black Friday sale is "buy 3 months, get 3 months free" on compounded GLP-1 plans. Here are the rules in plain terms:
- Dates: it runs now through 11:59 pm Central on Tuesday, December 1, 2026, then ends on its own.
- Who can use it: anyone in the 47 states we serve. You do not need a special link.
- What it covers: the 6-month plan ($495) and the 1-month plan ($139). The 3- and 12-month plans stay at regular prices. It also applies to tirzepatide, covered in our Black Friday tirzepatide guide.
- How to get it: there is no code. Take the short eligibility quiz, and the Black Friday price is applied at checkout automatically.
The sale lowers the price only. A licensed provider still needs to review your health history before anything is prescribed.
Black Friday semaglutide prices
| Plan length | Price | What it works out to |
|---|---|---|
| 1 month (regular) | $175 | $175 a month |
| 1 month (Black Friday) | $139 | $139 for the month |
| 3 months (regular) | $495 | $165 a month |
| 6 months (regular) | $875 | about $146 a month |
| 6 months (Black Friday) | $495 | about $82.50 a month, or $2.71 a day |
| 12 months (regular) | $1,188 | $99 a month |
Two things to keep in mind:
- It is paid up front. The $82.50 figure is $495 for 6 months spread over those months. It is not a monthly bill, and the plan does not auto-renew.
- It costs the same as the regular 3-month plan. If you were going to buy 3 months anyway, the sale gets you 6 for the same $495.
- The 1-month sale price is $139 through December 1, a lower-commitment way to start.
The regular 3-month ($495) and 12-month ($1,188) plans are not part of the sale. You can buy them through the plan picker on our semaglutide page.
For how semaglutide pricing works outside the sale, see our compounded semaglutide pricing guide.
What you get with each plan
The Black Friday 6-month and 1-month plans include:
- A review by a licensed U.S. provider
- Compounded semaglutide at any dose your provider prescribes, at the same price
- Injection supplies and a dosing guide
- Messaging with the care team, and check-ins before refills
- Free express shipping (1 to 5 business days) in plain packaging
There is no membership fee and no insurance is needed. It is cash pay, and many HSA and FSA cards are accepted. You are charged only if a provider prescribes, and the plan does not auto-renew. Treatment is available in 47 states, not Alaska, Louisiana or Mississippi.
💡 One flat price at every dose
Semaglutide doses usually go up over the first few months. Rx.com does not charge by strength, so stepping up your dose does not change what you pay.
How semaglutide works
Semaglutide is a GLP-1 receptor agonist. It copies a hormone your gut releases after you eat. Once a week, it helps you:
- Feel full sooner and stay full longer, because it slows how fast your stomach empties
- Feel less hungry, by acting on appetite centers in the brain
- Keep blood sugar steadier, by helping the pancreas release insulin when sugar is high
In the STEP 1 trial of the FDA-approved 2.4 mg weekly dose, adults lost an average of 14.9% of their body weight over 68 weeks, compared with 2.4% on placebo, alongside diet and exercise changes. That trial studied the FDA-approved medicine. Compounded semaglutide has not been tested in trials like it.
How dosing usually goes
Semaglutide starts low and goes up slowly to help your stomach adjust. The standard weekly schedule on the FDA label for weight management is:
| Weeks | Weekly dose |
|---|---|
| 1 to 4 | 0.25 mg |
| 5 to 8 | 0.5 mg |
| 9 to 12 | 1 mg |
| 13 to 16 | 1.7 mg |
| 17 and on | 2.4 mg (maintenance) |
Your provider may move faster or slower depending on how you feel. Our semaglutide dosage chart has more detail.
Questions to ask before you buy
A sale is a good time to start only if treatment is right for you. Ask yourself:
- Do I meet the usual criteria? GLP-1s for weight management are generally for adults with a BMI of 30 or more, or 27 or more with a weight-related condition.
- Do I have a reason I should not take it? People with a personal or family history of medullary thyroid cancer or MEN 2, or who are pregnant or trying to become pregnant, should not take semaglutide.
- Can I commit to 6 months? If you are unsure, the Black Friday 1-month plan ($139) lets you try it first, though it costs more per month.
- Is the seller legitimate? Read how to spot a legitimate GLP-1 deal.
Other ways to pay
Some people can pay less for an FDA-approved GLP-1 than any cash sale. Check these first:
- Insurance: if your plan covers a GLP-1 for weight loss, your copay may be lower.
- Manufacturer programs: the maker of FDA-approved semaglutide runs savings and self-pay options. Prices change, so check its site.
- Medicare: the CMS Medicare GLP-1 Bridge can bring a covered GLP-1 to $50 a month for eligible people.
Getting treatment through Rx.com
Now through December 1, 2026, Rx.com compounded semaglutide is $495 for 6 months, about $2.71 a day, down from $875. The provider review, medication, supplies and free express shipping are included, at one flat price for every dose, with no insurance needed. After December 1, regular prices apply.
Compounded medications are not FDA-approved. A licensed provider reviews your health history to decide whether semaglutide is right for you. To see if you qualify, take our short eligibility quiz. The Black Friday price is applied at checkout automatically.
🚨 When to Contact Your Healthcare Provider
Call your provider right away if any of these happen. Call 911 for trouble breathing, fainting or severe pain.
- Severe belly pain that will not go away, especially if it spreads to your back: possible pancreatitis.
- Pain in the upper right belly, fever, or yellow skin or eyes: possible gallbladder problem.
- Vomiting or diarrhea that keeps you from drinking fluids: risk of dehydration and kidney injury.
- Swelling of the face, lips or throat, or hives: possible allergic reaction.
- A lump in the neck, hoarseness or trouble swallowing.
Frequently Asked Questions
Do I need a promo code?
No. Take the short eligibility quiz, and the Black Friday price is applied at checkout automatically.
How much is semaglutide during the sale?
$495 for 6 months, paid once up front, about $2.71 a day. One month is $139 during the sale, down from $175. The 3- and 12-month plans stay at regular prices.
Can I get the price before Black Friday?
Yes. The sale is live now and runs through December 1, 2026, at 11:59 pm Central.
Does the price change when my dose goes up?
No. It is one flat price at every dose your provider prescribes.
Do I need insurance?
No. The plan price covers the provider visit, medication, supplies and shipping without insurance.
What if the provider says semaglutide is not right for me?
Then you are not charged. You are charged only if a provider prescribes.
Is compounded semaglutide the same as a brand-name drug?
No. Compounded semaglutide is not FDA-approved and is not the same as any brand-name medication.
Sources
- Wilding JPH, et al. Once-weekly semaglutide in adults with overweight or obesity (STEP 1). N Engl J Med. 2021;384:989-1002. nejm.org
- DailyMed. Semaglutide injection 2.4 mg, prescribing information. dailymed.nlm.nih.gov
- U.S. Food and Drug Administration. FDA's concerns with unapproved GLP-1 drugs used for weight loss. fda.gov
- U.S. Food and Drug Administration. Resolution of shortages of semaglutide injection products (February 2025). fda.gov
- Centers for Medicare & Medicaid Services. Medicare GLP-1 Bridge. cms.gov
- MedlinePlus. Semaglutide injection. medlineplus.gov
