How Much Is Compounded Semaglutide in 2026? Holiday Pricing Guide
What compounded semaglutide costs through Rx.com at regular prices, what the Black Friday "6 months for the price of 3" sale changes now through December 1, and how to tell which plan length actually fits your budget.
Through Rx.com, compounded semaglutide costs $175 for one month at regular prices, or $1,188 up front for a 12-month plan. Now through Tuesday, December 1, 2026, the Black Friday sale gives you 6 months for the price of 3: $495 for 6 months, about $2.71 a day, instead of the regular $875.
- Regular prices: $175 (1 month), $495 (3 months), $875 (6 months), $1,188 (12 months).
- Black Friday prices: $495 for the 6-month plan (a $380 saving) and $139 for 1 month (a $36 saving). The 3- and 12-month plans stay at regular prices.
- Sale dates: now through Tuesday, December 1, 2026, 11:59 pm Central. Regular prices apply after that.
- No code to enter. The price is applied at checkout automatically.
- One flat price at every dose. Your price does not go up when your dose does.
- The price covers the online provider review, medication, injection supplies and free express shipping.
- You are charged only if a licensed provider prescribes, and plans do not auto-renew.
Compounded semaglutide prices at Rx.com
Rx.com sells compounded semaglutide by plan length, not by dose. You pick how many months you want to cover, and the price stays the same whether your provider prescribes a starting dose or a higher maintenance dose.
| Plan | Regular price | Regular per month | Black Friday (through Dec 1) | Sale per month |
|---|---|---|---|---|
| 1 month | $175 | $175 | $139 | $139 |
| 3 months | $495 | $165 | Not on sale | n/a |
| 6 months | $875 | about $146 | $495 | $82.50 (about $2.71 a day) |
| 12 months | $1,188 | $99 | Not on sale | n/a |
Every price in the table is paid once, up front, for the whole plan. The "per month" columns simply divide that total by the number of months so you can compare plans.
What the Black Friday sale changes
For Black Friday 2026, Rx.com is running a "buy 3 months, get 3 months free" sale on the 6-month compounded GLP-1 plan. It is open to everyone. It is live now and ends on Tuesday, December 1, 2026, at 11:59 pm Central, the day after Cyber Monday.
- It applies to the 6-month and 1-month plans. Compounded semaglutide is $495 for 6 months, paid once up front, or $139 for 1 month. The 3- and 12-month plans stay at regular prices and are on our semaglutide page.
- It applies to compounded tirzepatide too. Our Black Friday tirzepatide guide has those numbers.
- There is no code. Take the short eligibility quiz and the Black Friday price is applied at checkout. Our guide on how to get the Black Friday price walks through it.
- After December 1, regular prices apply.
💡 Not sure yet?
The sale is live now, but there is no need to rush. You can read through the plans and take the eligibility quiz to see whether treatment may fit you, then decide before the sale ends on December 1.
How the per-month price really works
The "about $2.71 a day" or "$82.50 a month" figures you may see in Black Friday ads for our program are averages of the $495 6-month total, not a monthly bill. Here is what that means in practice:
- You pay $495 once, at the start, for 6 months of treatment.
- You are charged only if a provider prescribes. If you are not approved, you pay nothing.
- There is no monthly charge after that first payment for the plan.
- The plan does not auto-renew at the end of the 6 months.
That is a real saving if you plan to stay on treatment for at least 6 months. For a full year, the math changes: the sale 6 months ($495) plus 6 more regular months ($875) is $1,370, while the regular 12-month plan ($1,188) on our semaglutide page is $182 less. It is also a bigger up-front payment than a single month, so it is worth comparing plan lengths. Our guide to choosing a GLP-1 plan length this Black Friday walks through who each one suits.
What the price includes
One price covers the pieces most people need to start and stay on weekly semaglutide injections:
- A review by a licensed U.S. provider of your health history.
- Compounded semaglutide at whatever dose your provider prescribes, for the plan length you choose.
- Injection supplies and a dosing guide.
- Messaging with the care team, and check-ins before refills.
- Free express shipping (1 to 5 business days) in plain packaging.
There are no membership fees, separate visit fees, dose upcharges or shipping charges added at checkout. For a fuller breakdown, see what's included in the Black Friday plan.
Costs that are not part of the plan
A fair price comparison looks at your whole cost, not just the medication. Some things the plan does not cover:
- Lab work, if your own doctor or the provider asks for it.
- Other medicines, such as an anti-nausea prescription from your regular doctor.
- Sharps disposal containers, if your area requires a specific type.
- Ongoing care for other conditions such as diabetes or blood pressure, which stays with your regular doctor.
When another option may cost you less
Holiday pricing is only a good deal if it beats what you could pay elsewhere. Before you buy anything, check these paths:
- Your insurance. Some commercial plans cover brand-name GLP-1 medicines for weight management, and a manufacturer savings card can bring the copay as low as $25 a month for eligible people with commercial coverage.
- Medicare. The Medicare GLP-1 Bridge, which started July 1, 2026 and runs through December 31, 2027, sets a $50 copay on certain GLP-1 drugs for eligible Part D members.
- Manufacturer self-pay programs. Novo Nordisk's NovoCare Pharmacy sells its brand-name semaglutide pen at $199 a month for a new patient's first 2 months (offered through December 31, 2026), then $349 a month. Its semaglutide pill starts at $149 a month at the lowest dose.
If you have good coverage, one of those routes may be the smarter choice, and we would rather you know that. Our guide to the first-month cost of GLP-1 treatment compares the starting costs side by side.
What compounded semaglutide is
Compounded semaglutide is made by a licensed pharmacy for an individual patient with a prescription. Compounded medications are not FDA-approved, which means the FDA does not review them for safety, effectiveness or quality before they are sold.
The FDA declared the semaglutide shortage resolved on February 21, 2025. A 503A pharmacy may still compound semaglutide for an individual patient when a prescriber documents a clinical need, such as a dose or formulation change. The FDA also warns about unapproved GLP-1 products sold online, especially products labeled "for research use only" and salt forms such as semaglutide sodium or semaglutide acetate. Our compounded semaglutide safety guide covers what to look for.
Getting treatment through Rx.com
Rx.com offers compounded semaglutide with a provider review, medication, supplies and free express shipping included. It is one flat price at every dose, and no insurance is needed. Now through Tuesday, December 1, 2026, the Black Friday sale brings the 6-month plan to $495, about $2.71 a day, instead of the regular $875. See if you qualify.
Compounded medications are not FDA-approved. A licensed provider reviews your health history to decide whether semaglutide is right for you, and you are charged only if you are prescribed. Treatment is available in 47 states, not Alaska, Louisiana or Mississippi. If you are not sure where to start, our eligibility quiz takes a few minutes.
🚨 When to Contact Your Healthcare Provider
Call your provider right away if any of these happen. Call 911 for trouble breathing, fainting or severe pain.
- Severe belly pain that will not go away, with or without vomiting, especially if it spreads to your back: possible pancreatitis.
- Pain in the upper right belly, fever, or yellow skin or eyes: possible gallbladder problem.
- Vomiting or diarrhea that keeps you from drinking fluids: risk of dehydration and kidney injury.
- Swelling of the face, lips or throat, hives or trouble swallowing: possible allergic reaction.
- A lump in the neck, hoarseness or trouble swallowing: tell your provider promptly.
Frequently Asked Questions
How much is compounded semaglutide per month in 2026?
Through Rx.com it is $175 for a single month, or $1,188 up front for a 12-month plan (about $99 a month). During the Black Friday sale, now through December 1, 2026, a single month is $139 and the 6-month plan is $495 up front, which averages $82.50 a month or about $2.71 a day.
Is the Black Friday price charged every month?
No. You pay $495 once at the start for 6 months of treatment. The per-month and per-day figures just divide that total. The plan does not auto-renew.
Does the price go up at higher doses?
No. Rx.com charges one flat price at every dose. Only the plan length changes the price.
When does the holiday price end?
The Black Friday sale runs now through Tuesday, December 1, 2026, at 11:59 pm Central. It ends automatically, and regular prices apply after that.
Do I pay before a provider reviews me?
You are charged only if a licensed provider prescribes treatment for you.
Will my plan renew automatically?
No. Rx.com plans do not auto-renew. When your plan ends, you choose whether to continue.
Is compounded semaglutide FDA-approved?
No. Compounded medications are not FDA-approved and are not the same as any brand-name medication. A licensed pharmacy prepares them for individual patients with a prescription.
Sources
- U.S. Food and Drug Administration. FDA's concerns with unapproved GLP-1 drugs used for weight loss. fda.gov
- U.S. Food and Drug Administration. Resolution of semaglutide injection product shortage and supply status (February 21, 2025). fda.gov
- Centers for Medicare & Medicaid Services. Medicare GLP-1 Bridge. cms.gov
- Novo Nordisk. NovoCare savings offer and self-pay pricing. novocare.com
- MedlinePlus. Semaglutide injection. medlineplus.gov
