MOTS-c Black Friday Deal 2026: Prescription MOTS-c, Buy 3 Months Get 3 Free
Six months of prescription MOTS-c for $597, or $199 month to month, through Friday, November 27, 2026. Here is what the deal includes, what MOTS-c has and has not been shown to do, and how ordering works.
Rx.com's Black Friday MOTS-c deal is "buy 3 months, get 3 free": 6 months of prescription MOTS-c for $597 (about $99.50 a month), or $199 month to month, through Friday, November 27, 2026. It is compounded for you by a licensed U.S. 503A pharmacy after a U.S.-licensed provider reviews your online intake, and you are billed only if the provider prescribes it.
- Sale: 6 months for $597 (3 x $199) or $199 month to month.
- Ends Friday, November 27, 2026. No code needed: the sale price is the price at checkout.
- The 6-month plan is one payment up front, and all 6 months must be shipped within 6 months of purchase.
- Single-ingredient MOTS-c, injected under the skin, labeled with your name.
- MOTS-c is not FDA approved. Most of the evidence comes from cells and mice.
- Not available in Louisiana or Mississippi.
Black Friday saleEnds Fri, Nov 27
Buy 3 months, get 3 free
6 months of prescription MOTS-c for $597 ($99.50/mo), or $199 month to month. Prescribed by a U.S.-licensed provider, compounded by a licensed U.S. 503A pharmacy. No code needed, billed only if prescribed. Not FDA approved.
Prescription MOTS-c from Rx.com, from $99.50/mo. Online visit with a U.S.-licensed provider, compounded by a licensed U.S. 503A pharmacy. Not FDA approved.
See plans →See if MOTS-c is right for you
The MOTS-c Black Friday deal
The offer is simple. Pay for 3 months of MOTS-c and get 3 more free. That is 6 months for $597, which works out to $99.50 a month. If you would rather not commit, month to month is $199.
| 6-month plan | Month to month | |
|---|---|---|
| Price | $597, one payment | $199 a month |
| Effective monthly cost | $99.50 | $199 |
| Months covered | 6 (3 paid, 3 free) | 1 at a time |
| Claim window | All 6 months must ship within 6 months of purchase | Not applicable |
| Billed if not prescribed? | No | No |
| Code needed? | No | No |
A few plain facts about the 6-month plan. It is one payment up front. All 6 months have to be shipped within 6 months of the date you buy, and any months you have not claimed by then expire. So it suits someone ready to start soon, not someone buying now to start next summer.
The sale runs through Friday, November 27, 2026. Prices after November 27 may change. The same prices apply to all three peptides Rx.com offers: BPC-157, MOTS-c and Epitalon. See the Black Friday peptide deals hub to compare them side by side.
What MOTS-c is
MOTS-c is a short peptide that your body makes on its own. What makes it unusual is where its code lives: in the DNA of your mitochondria, the parts of your cells that turn food into energy. Most proteins are coded in the cell's main DNA, so MOTS-c belongs to a small group scientists call mitochondrial-derived peptides.
Researchers first described it in 2015. Since then, it has been studied mostly for its role in how cells handle sugar and energy. Prescription MOTS-c from Rx.com is a lab-made version of that peptide, compounded as a single-ingredient injection given under the skin.
What the evidence shows (and does not)
This is the part a good seller should be honest about. Most of what is known about MOTS-c comes from cells and mice. Human data mostly measure the MOTS-c people already make, not what happens when someone is treated with it.
| What was studied | Where | What it found |
|---|---|---|
| Insulin sensitivity | Mice | Animal studies suggest MOTS-c improved how muscle responds to insulin |
| Diet-induced weight gain | Mice | Mice on a high-fat diet gained less weight when given MOTS-c |
| Exercise capacity | Mice | Treated mice, including older mice, showed better physical performance |
| Natural MOTS-c levels | Humans | Levels rise with exercise and tend to be lower in some groups; these studies did not give people MOTS-c |
What that means for you: MOTS-c is studied for metabolism and exercise, and early research is interesting. It is not proven to cause weight loss, improve diabetes or slow aging in people. Anyone promising those results is selling past the evidence. For a closer look at known risks, read MOTS-c side effects and safety.
Why people still choose it
Some adults want to try a peptide with early metabolic research behind it, under a provider's care and from a real pharmacy, rather than guess with an unlabeled vial. That is the choice this deal is built for. Your provider can talk through whether the uncertainty is acceptable for you.
Is prescription MOTS-c legal?
MOTS-c is not FDA approved. On October 28, 2026, the FDA and HHS issued an interim enforcement-discretion policy. It lets licensed 503A pharmacies and physicians compound six peptides, including MOTS-c, for individual patients with a prescription, as long as they meet quality, labeling and safety-reporting conditions.
That policy is not approval. It is temporary, it can change, and states may set their own rules. "Research use only" products sold to consumers are outside it. Our guide are peptides legal in the U.S.? covers the details.
Prescription MOTS-c vs research vials
Black Friday will bring plenty of cheap MOTS-c vials labeled "for research use only." Here is how they compare with a prescription.
| Prescription MOTS-c (Rx.com) | "Research use only" vial | |
|---|---|---|
| Provider review | Yes, a U.S.-licensed provider | No |
| Who makes it | A licensed, state-inspected U.S. 503A pharmacy | Often unknown |
| Ingredients | MOTS-c only, nothing blended | Unverified |
| Label | Your name and what the pharmacy label lists | "Not for human consumption" |
| Covered by the October 2026 policy | Yes, as a 503A prescription | No |
| Black Friday price | $99.50 a month on the 6-month plan | Varies |
A vial that says "not for human consumption" means exactly that. No one has checked it is right for you, and no pharmacy stands behind what is in it. See how to buy peptides safely and peptide Black Friday red flags before you buy anywhere.
Who should talk to a provider first
Your provider decides whether MOTS-c fits you, and they may say no. Be upfront in your intake, especially if any of these apply:
- You take diabetes medicine (including insulin or GLP-1 medicines). Because MOTS-c is studied for blood sugar, it may add to their effect. Talk to your provider.
- You are pregnant, trying to get pregnant or breastfeeding. There is no safety data.
- You have active cancer or a history of cancer. Peptides that affect cell growth signals raise questions no one has answered yet.
- You are under 18.
There is also no dose in this article on purpose. Your pharmacy label lists your dose, and your provider sets it.
6 months or month to month?
| Pick the 6-month plan if | Pick month to month if |
|---|---|
| You want the lowest cost per month on this sale ($99.50) | You want to try MOTS-c before committing |
| You plan to start soon and keep going | Your provider wants to check in before a longer course |
| You can use all 6 months within 6 months of buying | You may not start for a while |
Over 6 months, the 6-month plan costs $597 and paying monthly costs $1,194. That is a $597 difference, or 3 free months. Our 6-month vs month-to-month guide walks through it.
Lock in 6 months of MOTS-c for $597 or start month to month at $199
Ordering through Rx.com
Here is how it works:
- Answer an online intake. Health history, medicines and goals. It takes a few minutes.
- A U.S.-licensed provider reviews it. They decide whether MOTS-c is right for you. They may say no.
- You are billed only if it is prescribed.
- A licensed, state-inspected U.S. 503A pharmacy compounds it for you. Single-ingredient MOTS-c, labeled with your name. The package holds the peptide and what the pharmacy label lists.
The Black Friday price is $597 for 6 months (about $99.50 a month) or $199 month to month, through Friday, November 27, 2026. There is no code to enter. The 6-month plan is one payment up front, and all 6 months must be shipped within 6 months of purchase. Prices after November 27 may change. Not available in Louisiana or Mississippi.
MOTS-c is not FDA approved. It is compounded under the FDA's interim enforcement-discretion policy for individual prescriptions. You can see the plans on our MOTS-c page, compare all three peptides at buy peptides online, or read the Epitalon and BPC-157 Black Friday deals.
🚨 When to Contact Your Healthcare Provider
Call your provider if any of these happen while using MOTS-c. Call 911 for trouble breathing, fainting or chest pain.
- Shakiness, sweating, confusion, hunger or a fast heartbeat: possible low blood sugar, especially if you take diabetes medicine.
- Swelling of the face, lips or throat, hives or trouble swallowing: possible allergic reaction.
- Redness, heat, swelling or pus at the injection site, or a fever: possible infection.
- A new lump, unusual weight change or symptoms that worry you.
- You think you used too much: call Poison Control at 1-800-222-1222.
You can also report side effects to the FDA through MedWatch.
Black Friday saleEnds Fri, Nov 27
Buy 3 months, get 3 free
6 months of prescription MOTS-c for $597 ($99.50/mo), or $199 month to month. Prescribed by a U.S.-licensed provider, compounded by a licensed U.S. 503A pharmacy. No code needed, billed only if prescribed. Not FDA approved.
Frequently Asked Questions
How much is MOTS-c on Black Friday?
$597 for 6 months (buy 3, get 3 free), about $99.50 a month, or $199 month to month. The sale runs through Friday, November 27, 2026.
Do I need a code?
No. The sale price is the price shown at checkout.
Do I have to use all 6 months right away?
All 6 months must be shipped within 6 months of purchase. Months you have not claimed by then expire, so the plan works best if you plan to start soon.
Is MOTS-c FDA approved?
No. MOTS-c is not FDA approved. Licensed 503A pharmacies may compound it for individual prescriptions under an interim FDA policy from October 28, 2026, which is temporary and can change.
Will MOTS-c help me lose weight?
That is not known. Mice on a high-fat diet gained less weight with MOTS-c, but there are no solid human treatment studies. Talk to your provider about realistic expectations.
What if the provider says no?
You are billed only if a provider prescribes it. If MOTS-c is not right for you, you are not charged for it.
Can I use MOTS-c with diabetes medicine?
Only if your provider agrees. MOTS-c is studied for blood sugar effects, so it may add to diabetes medicines. Tell your provider everything you take.
Sources
- Lee C, et al. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metabolism, 2015. pubmed.ncbi.nlm.nih.gov
- Reynolds JC, et al. MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. Nature Communications, 2021. pubmed.ncbi.nlm.nih.gov
- U.S. Food and Drug Administration. Human drug compounding. fda.gov
- U.S. Food and Drug Administration. BeSafeRx: Considering an online pharmacy? fda.gov
- U.S. Food and Drug Administration. MedWatch: The FDA Safety Information and Adverse Event Reporting Program. fda.gov
