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Apidra Solostar Pen — prescription drug image

Apidra Solostar

Apidra SoloStar 3ML of 100UNIT/ML

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What is Apidra Solostar?

Apidra Solostar is a brand of insulin glulisine, a fast-acting insulin analog used to control high blood sugar in individuals with diabetes mellitus. It is administered via the Solostar, a pre-filled, disposable injection pen, designed for ease of use and precise dosing. Apidra Solostar begins to work within minutes of administration, making it an effective option for managing blood glucose levels at meal times.

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What is Apidra Solostar ?

Apidra Solostar is a brand of insulin glulisine, a fast-acting insulin analog used to control high blood sugar in individuals with diabetes mellitus. It is administered via the Solostar, a pre-filled, disposable injection pen, designed for ease of use and precise dosing. Apidra Solostar begins to work within minutes of administration, making it an effective option for managing blood glucose levels at meal times.
  • Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Dry mouth, increased thirst, muscle cramps, nausea, vomiting, uneven heartbeat
  • Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing, tiredness
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, or heart failure.
  • This medicine may cause the following problems:Low blood sugar or low potassium levels in the bloodFluid retention or heart failure (when used with a thiazolidinedione [TZD] medicine)
  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Never share insulin pens or needles with anyone. Sharing these can pass hepatitis virus, HIV, and other illnesses from one person to another.
What is the difference between Apidra and Apidra SoloStar?
Apidra and Apidra SoloStar contain the exact same medicine, insulin glulisine, but come in different delivery forms. Apidra is available as a vial for use with a syringe, insulin pump, or IV administration under medical supervision. Apidra SoloStar is a prefilled, disposable pen meant only for subcutaneous (under-the-skin) injection — it is not used with a pump or given intravenously.
How fast does Apidra insulin start working?
Apidra is a rapid-acting insulin analog, designed to start lowering blood sugar quickly after injection. It's typically given within about 15 minutes before a meal or up to 20 minutes after starting a meal, to help match insulin action with the rise in blood sugar from eating. Your provider will set the exact timing and dose that's right for you.
Can Apidra SoloStar be used in an insulin pump?
No. The Apidra SoloStar pen is labeled for subcutaneous injection only and is not designed for use in an insulin pump or for IV administration. Patients who need continuous subcutaneous infusion (pump) or IV delivery use the Apidra vial form instead, under their provider's direction.
How long does an opened Apidra SoloStar pen last before it must be discarded?
Once an Apidra SoloStar pen is in use, it should be kept at room temperature (not refrigerated) and discarded 28 days after the first use, even if it still contains insulin. Unopened pens should be kept refrigerated until you're ready to start using one.
Is Apidra the same as Humalog or NovoLog?
Apidra, Humalog, and NovoLog are all rapid-acting insulin analogs used to help control blood sugar around mealtimes, but they are different medicines: Apidra contains insulin glulisine, Humalog contains insulin lispro, and NovoLog contains insulin aspart. They are not automatically interchangeable, and switching between them should only be done under a provider's guidance.
How much does Apidra Solostar cost without insurance?
The price of Apidra Solostar without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Apidra Solostar?
Common side effects of Apidra Solostar may include: Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Dry mouth, increased thirst, muscle cramps, nausea, vomiting, uneven heartbeat, Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing, tiredness. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Apidra Solostar?
Generic versions may be available for Apidra Solostar. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Apidra Solostar on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Apidra Solostar?
The cheapest pharmacy for Apidra Solostar depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Apidra Solostar near you.

Apidra Solostar Coupons & Prices

Apidra SoloStar 3ML of 100UNIT/ML

Prescriptions & Refills
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Apidra Solostar Pen — prescription drug image
Prescription
Apidra Solostar 3ml of 100unit/ml (1)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for an Apidra SoloStar coupon? Apidra SoloStar is a prefilled, disposable insulin pen containing insulin glulisine, a rapid-acting insulin analog used to help manage blood sugar in adults and children with diabetes, and pricing can vary a lot from pharmacy to pharmacy — enter your ZIP above to see today's price and compare it against the manufacturer's savings program.

What Is Apidra SoloStar and How Does It Work?

Apidra SoloStar is the prefilled pen version of Apidra (insulin glulisine), a rapid-acting human insulin analog. It's FDA-approved to improve blood sugar control in adults with type 1 or type 2 diabetes, and in children (4 years of age and older) with type 1 diabetes. Apidra is typically injected under the skin within about 15 minutes before or 20 minutes after a meal; the medicine itself can also be given by continuous subcutaneous insulin pump or, in a hospital setting, intravenously under medical supervision.

The SoloStar pen specifically is a single-patient-use, disposable device holding a 3 mL (300 unit) U-100 cartridge, and it is intended for subcutaneous injection only — it is not designed or labeled for use in an insulin pump or for IV administration. Patients who need pump or IV delivery use the Apidra vial-and-syringe form instead, under a provider's direction.

Apidra SoloStar Savings Card vs. an Rx.com Cash Coupon

Sanofi, the maker of Apidra, offers an official manufacturer savings program through its Apidra website; terms, eligibility, and any caps can change, so check the current details directly on the manufacturer's site. Like most manufacturer copay cards, it's generally intended for patients with commercial (private) insurance and typically excludes people enrolled in Medicare, Medicaid, or other government health programs.

An Rx.com cash coupon works differently: it's not tied to your insurance status at all, so it can help if you're uninsured, on Medicare, or if your manufacturer card is declined at the counter for any reason. Generic and lower-cost insulin options can change over time, so ask your pharmacist whether a substitutable option is available for insulin glulisine at your pharmacy — comparing the manufacturer card, your insurance copay, and the Rx.com coupon price is the best way to find the lowest out-of-pocket cost.

Apidra SoloStar vs. Other Insulins

Apidra SoloStar is one of several rapid-acting insulin options prescribed to cover mealtime blood sugar spikes. Other rapid-acting analogs your provider may consider include Humalog (insulin lispro) and NovoLog (insulin aspart); the vial form of the same medicine, Apidra, is used when pump or IV delivery is needed. Many patients on a rapid-acting insulin also use a separate long-acting, basal insulin such as Lantus SoloStar or Toujeo SoloStar to cover blood sugar between meals and overnight.

These products are not interchangeable on your own — they differ in onset, duration, and dosing, and only your provider can determine which combination and dose is right for you. This is not medical advice; talk to your provider or pharmacist before switching between insulin products.

Safety Information

Apidra SoloStar does not carry an FDA boxed warning, but the label includes several important warnings. A SoloStar pen must never be shared between patients, even if the needle is changed, because of the risk of transmitting blood-borne infections. Hypoglycemia (low blood sugar) is the most common and most serious risk with any insulin and can be severe or life-threatening; know the signs and how to treat it. The SoloStar pen is not to be used for IV injection — IV use requires the vial-and-syringe form under medical supervision with glucose monitoring, and insulin should never be diluted or mixed inside the pen itself.

Other label warnings include an increased risk of fluid retention and heart failure when insulin is combined with TZD medicines (rosiglitazone or pioglitazone), a risk of low potassium (hypokalemia), and the need to adjust insulin doses during illness, stress, or kidney or liver problems, since these can change how much insulin you need. Store unopened pens refrigerated; once a pen is in use, keep it at room temperature and discard it 28 days after first use, even if it still contains insulin. This is general information, not medical advice — follow your provider's specific instructions for your dose and monitoring.

Sources & accuracy

This Apidra Solostar information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Apidra Solostar on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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