Climara Pro
Climara Pro
What is Climara Pro?
Looking for information on Climara Pro, hormone replacement therapy, or menopause treatment options? Climara Pro is a prescription hormone replacement therapy (HRT) patch that combines estradiol and levonorgestrel to help relieve menopause symptoms such as hot flashes, night sweats, and vaginal dryness. Learn about Climara Pro uses, dosage, side effects, benefits, and how to get a Climara Pro prescription online through Rx.com.
Side Effects
- Rapid weight gain, swelling in your hands, ankles, or feet
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Warnings
- Pregnancy after menopause is not likely, but if you think you could be pregnant, tell your doctor. This medicine could harm an unborn baby.
- Tell your doctor if you are breastfeeding, or if you have kidney disease, asthma, diabetes, edema, endometriosis, seizures, migraine headaches, porphyria, lupus, thyroid problems, heart disease, edema (swelling), high blood pressure, high cholesterol, hereditary angioedema, or a history of cancer. Tell your doctor if you have had your uterus (womb) removed (hysterectomy) or if you are having surgery that will require inactivity for a long time.
- This medicine may cause the following problems:Increased risk of heart attack, stroke, or blood clotsIncreased risk of endometrial, breast, or uterine cancerIncreased risk of dementia (especially in women 65 years of age or older)Increased risk of gallbladder diseaseEye or vision problemsHigh blood pressureHigh cholesterol or fats in the blood
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
Prescription savings · · · ·
What is Climara Pro ?
Looking for information on Climara Pro, hormone replacement therapy, or menopause treatment options? Climara Pro is a prescription hormone replacement therapy (HRT) patch that combines estradiol and levonorgestrel to help relieve menopause symptoms such as hot flashes, night sweats, and vaginal dryness. Learn about Climara Pro uses, dosage, side effects, benefits, and how to get a Climara Pro prescription online through Rx.com.
- Rapid weight gain, swelling in your hands, ankles, or feet
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blurred or other changes in vision
- Breast pain, lump, or tenderness
- Unusual vaginal bleeding, spotting, discharge, or itching
- Redness, pain, burning, or itching in or near your vagina
- Fever, chills, cough, runny or stuffy nose, sore throat, and body aches
- Chest pain that may spread, coughing up blood, trouble breathing
- Numbness or weakness on one side of your body, sudden or severe headache, problems with speech or walking
- Pregnancy after menopause is not likely, but if you think you could be pregnant, tell your doctor. This medicine could harm an unborn baby.
- Tell your doctor if you are breastfeeding, or if you have kidney disease, asthma, diabetes, edema, endometriosis, seizures, migraine headaches, porphyria, lupus, thyroid problems, heart disease, edema (swelling), high blood pressure, high cholesterol, hereditary angioedema, or a history of cancer. Tell your doctor if you have had your uterus (womb) removed (hysterectomy) or if you are having surgery that will require inactivity for a long time.
- This medicine may cause the following problems:Increased risk of heart attack, stroke, or blood clotsIncreased risk of endometrial, breast, or uterine cancerIncreased risk of dementia (especially in women 65 years of age or older)Increased risk of gallbladder diseaseEye or vision problemsHigh blood pressureHigh cholesterol or fats in the blood
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Unusual vaginal bleeding, spotting, discharge, or itching
- Vision changes
Climara Pro Coupons & Prices
Climara Pro
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Climara Pro prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 1 box (4 weekly patches), 0.045-0.015mg/day · Box | 4 | $349.99 | $249.22 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
Looking for a Climara Pro coupon? Climara Pro is a brand-name, once-weekly transdermal patch that combines two hormones (estradiol and levonorgestrel) to treat moderate-to-severe menopause symptoms and help prevent postmenopausal osteoporosis in women who still have a uterus. Because there is no generic version yet, the price can be high, so it pays to compare. Enter your ZIP code above to see today's Rx.com cash price at pharmacies near you, and use our free discount coupon at the counter, no insurance required.
What is Climara Pro and how does it work?
Climara Pro is a combination hormone replacement therapy (HRT) skin patch. It delivers about 0.045 mg per day of estradiol (an estrogen) and 0.015 mg per day of levonorgestrel (a progestin) through the skin, and it is worn and replaced once a week. The estrogen eases menopausal symptoms and helps protect bone, while the levonorgestrel is added to protect the lining of the uterus (the endometrium) from estrogen-related overgrowth.
It is FDA-approved for use in postmenopausal women who still have a uterus for two purposes: (1) treating moderate-to-severe vasomotor symptoms such as hot flashes and night sweats, and (2) helping prevent postmenopausal osteoporosis. For bone health, guidelines suggest considering non-estrogen options first and reserving Climara Pro for women at significant risk. This is general information, not medical advice, so talk with your provider about whether it fits your situation.
Climara Pro cost: manufacturer savings card vs. Rx.com cash coupon
There are two main ways to lower what you pay for Climara Pro. Bayer, the manufacturer, offers a savings card. Manufacturer copay cards like this are generally limited to people with commercial (private) insurance and typically exclude anyone with Medicare, Medicaid, or other government coverage, and terms and eligibility vary. You can review the official offer and current terms at the Bayer savings card page.
The Rx.com cash coupon works differently. It is a discount coupon you can use whether or not you have insurance, which makes it a good option if you are uninsured, on Medicare, or if the manufacturer card is declined at the pharmacy. You cannot combine a cash coupon with insurance on the same fill, but you can compare which one costs less. Because Climara Pro has no generic, the brand patch is the only version to price. Enter your ZIP above to see today's Rx.com price near you.
Climara Pro alternatives and related patches
If cost or availability is a concern, ask your provider whether a related estrogen or estrogen-plus-progestin product might work for you. Options in the same general family include:
- Climara and Vivelle-Dot - estradiol-only patches (a separate progestin may be needed if you have a uterus)
- CombiPatch - an estradiol plus norethindrone combination patch
- estradiol - available as a lower-cost generic in several forms
- Premarin, Prempro, and Premphase - oral estrogen and estrogen-plus-progestin options
These products are not identical in hormones or dosing, so only your provider can say which is appropriate. Compare prices for each on Rx.com by entering your ZIP.
Climara Pro safety and warnings
Climara Pro carries a boxed warning, the FDA's strongest, covering cardiovascular risks (stroke, blood clots in the legs or lungs, and heart attack with estrogen-plus-progestin therapy), probable dementia in women 65 and older, breast cancer, and endometrial cancer. It should not be used to prevent heart disease or dementia. The general guidance is to use the lowest effective dose for the shortest time needed, and to report any postmenopausal vaginal bleeding to your provider promptly.
It should not be used if you have undiagnosed abnormal genital bleeding; a known or suspected estrogen- or progestin-dependent cancer such as breast cancer; a current or past history of blood clots (DVT/PE) or arterial clots (stroke, heart attack); liver disease; certain clotting disorders (such as protein C, protein S, or antithrombin deficiency); pregnancy; or a known severe allergic reaction to the product. This is a summary, not medical advice - review your full history and all warnings with your provider before starting or stopping this medicine.
This Climara Pro information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Climara Pro on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.