Dofetilide Coupons & Prices

Looking for a dofetilide coupon? Dofetilide (brand name Tikosyn) is a generic antiarrhythmic medication, and pharmacy cash prices for generics like this can vary widely from one pharmacy to the next. Rx.com compares pricing across 60,000+ pharmacies so you can see today's price at pharmacies near you before you fill a prescription — enter your ZIP above to get started. Because dofetilide can only be started or restarted under in-hospital monitoring, be sure to fill it at the pharmacy your prescribing hospital or clinic recommends.

What is dofetilide and how does it work?

Dofetilide is a Class III antiarrhythmic drug that works by selectively blocking a cardiac potassium channel (IKr). It is FDA-approved to help maintain normal sinus rhythm (delay the return of atrial fibrillation or atrial flutter) in patients who have already been converted back to a normal heart rhythm after more than one week of AFib/AFL, and it can also be used to convert AFib/AFL to normal sinus rhythm. Because of its risk profile, doctors generally reserve it for patients with symptoms where restoring a normal rhythm is the preferred approach.

The generic name is dofetilide; the brand name is Tikosyn. This is not a controlled substance.

Dofetilide cost and coupon savings

Dofetilide is available as a generic, and generic drug prices can differ substantially from pharmacy to pharmacy — sometimes by a wide margin for the exact same medication. That makes comparing prices worthwhile before you fill or transfer a prescription. There is currently no manufacturer savings card for dofetilide or Tikosyn on file; enter your ZIP code above to see today's price at pharmacies near you and find the lowest option in your area.

Because dofetilide requires certified prescribers and pharmacies enrolled in its restricted distribution program, not every pharmacy stocks or dispenses it — confirm with your hospital or prescriber which certified pharmacy will fill your prescription, then use Rx.com to compare pricing among the pharmacies that carry it.

Dofetilide vs. other antiarrhythmic options

Dofetilide is one of several medications used to manage AFib/AFL rhythm control. Other antiarrhythmics your doctor may consider or that you may see mentioned alongside dofetilide include amiodarone, sotalol, flecainide, and propafenone. Many AFib patients are also prescribed an anticoagulant such as warfarin or Eliquis (apixaban) to reduce stroke risk.

These medications differ in how they're monitored, dosed, and combined with other therapies, so the right choice depends on your specific heart rhythm history, kidney function, and other medications — this is a decision for your cardiologist, not something to switch on your own.

Dofetilide safety information

Dofetilide carries a boxed warning: it must be started, and restarted after any interruption, in a facility with continuous ECG monitoring and staff trained to manage life-threatening heart rhythm problems, for a minimum of three days. This is because of a dose-dependent risk of QT-interval prolongation and dangerous ventricular arrhythmias, including torsades de pointes. Dosing is individualized based on kidney function (creatinine clearance) and QT interval, and dofetilide is not appropriate for people with certain baseline QT prolongation, severe kidney impairment, congenital or acquired long QT syndrome, or who take certain interacting medications.

Dofetilide is only available through a restricted program requiring certified prescribers and pharmacies. This is general information, not medical advice — always follow your care team's specific instructions and report any new symptoms right away.