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Drysol

Drysol 60ML of 20%

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What is Drysol?

Hypercare is a miscellaneous topical agent used to treat patients with excessive sweating. Aluminum chloride hexahydrate is the generic version of Hypercare. Hypercare costs around $10 for a supply of 1, 60 ml of 20% applicator. An easy way to reduce the Hypercare price is to use our free Rx.com Hypercare discount card.

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What is Drysol ?

Hypercare is a miscellaneous topical agent used to treat patients with excessive sweating. Aluminum chloride hexahydrate is the generic version of Hypercare. Hypercare costs around $10 for a supply of 1, 60 ml of 20% applicator. An easy way to reduce the Hypercare price is to use our free Rx.com Hypercare discount card.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
What is Drysol used for?
Drysol is a prescription-strength topical antiperspirant used for hyperhidrosis, meaning excessive sweating. Its labeling indicates it for severe, recalcitrant hyperhidrosis. It is most often used under the arms, and it is also used on the palms and soles. Its active ingredient, aluminum chloride hexahydrate, is generally considered first-line therapy for primary focal hyperhidrosis as an ingredient class, and topical aluminum chloride is usually tried before iontophoresis, botulinum toxin injections, oral medicines, or surgery. Drysol is not a deodorant.
How do you apply Drysol for the best results?
Drysol is applied to completely dry skin at bedtime, then washed off in the morning. Skin that is even slightly damp is much more likely to sting. Let it dry fully before dressing, and remember the solution is alcohol-based and flammable, so keep it away from flame and smoking while it dries. Do not cover the area with plastic wrap unless your clinician specifically tells you to. Do not apply it to broken, irritated, or freshly shaved or waxed skin; wait at least 24 to 48 hours after shaving. Follow the directions on your own label, and ask your pharmacist or clinician if anything is unclear.
Why does Drysol burn or itch, and how can I prevent it?
Stinging, burning, itching, prickling, and general skin irritation are the most common side effects of Drysol. Irritation is more likely when the skin is damp, freshly shaved or waxed, already irritated, or covered up after application. To reduce it, apply only to completely dry skin at bedtime, wash the area in the morning, avoid applying within 24 to 48 hours of shaving, and do not occlude the area with plastic wrap unless directed. If you get severe irritation, a rash, or signs of infection, stop using it and contact your clinician.
Is Drysol available over the counter or do you need a prescription?
Drysol requires a prescription. Drysol and Drysol Dab-O-Matic are 20% aluminum chloride hexahydrate. Other aluminum chloride hexahydrate products are also prescription-only, including Hypercare (labeled 15% w/v in its package insert) and Xerac AC at 6.25% — Xerac AC is a prescription product despite being the lowest of these strengths. Strength by itself does not decide prescription status: Certain Dri Clinical Strength is sold over the counter, and its Drug Facts label lists aluminum chloride 15%. If an over-the-counter antiperspirant is not controlling your sweating, that is worth raising with your clinician.
Is there a generic version of Drysol?
Not in the usual sense. Drysol is marketed without an FDA New Drug Application, so there is no approved generic application behind it and no AB-rated generic a pharmacist could automatically substitute for it. Unbranded aluminum chloride hexahydrate solutions are sold and do appear in pharmacy databases, but whether any of them is an appropriate substitute for your prescription is a decision for your pharmacist and prescriber. Because prices for the same product vary quite a bit from pharmacy to pharmacy, it is still worth comparing what different pharmacies charge with a cash coupon. Enter your ZIP above to see today's price near you.
How much does Drysol cost without insurance?
The price of Drysol without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Drysol?
Common side effects of Drysol may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Drysol?
Generic versions may be available for Drysol. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Drysol on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Drysol?
The cheapest pharmacy for Drysol depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Drysol near you.

Drysol Coupons & Prices

Drysol 60ML of 20%

Prescriptions & Refills
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Drysol Bottle — prescription drug image
Prescription
Drysol 60ml of 20% (1)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Drysol is a prescription-strength topical antiperspirant used for hyperhidrosis (excessive sweating), and a Drysol coupon from Rx.com can lower what you pay at the pharmacy counter when you are paying cash. Drysol is aluminum chloride hexahydrate solution; its labeling indicates it for severe, recalcitrant hyperhidrosis. Topical aluminum chloride hexahydrate as an ingredient class is generally the first thing clinicians reach for in primary focal hyperhidrosis, before options like iontophoresis, botulinum toxin injections, oral medicines, or surgery. Prices for the same bottle vary quite a bit from one pharmacy to the next, so it pays to compare. Enter your ZIP above to see today's price near you.

What is Drysol and how does it work?

Drysol is a topical solution of aluminum chloride hexahydrate, an aluminum-salt antiperspirant and astringent. It is applied to the skin to reduce excessive sweating, most often under the arms (axillary hyperhidrosis), and it is also used on the palms and soles. Drysol's own labeling indicates it for severe, recalcitrant hyperhidrosis. It is not a deodorant and it is not a pill; it works on the skin where you apply it.

Drysol has been marketed for many years as a prescription antiperspirant rather than as a product approved under an FDA New Drug Application. Drysol and Drysol Dab-O-Matic are 20% aluminum chloride hexahydrate. Other marketed aluminum chloride hexahydrate products include Hypercare, labeled 15% w/v in its package insert (some drug databases list it as 20%), and Xerac AC at 6.25% — both of which are also prescription products. Strength alone does not determine whether a product needs a prescription: Certain Dri Clinical Strength is sold over the counter, and its Drug Facts label lists aluminum chloride 15% — a higher number than prescription-only Xerac AC. Aluminum chloride hexahydrate as an ingredient is generally regarded as first-line therapy for primary focal hyperhidrosis. In dermatology practice the ingredient is also used for other purposes, such as stopping minor skin bleeding; this page describes the antiperspirant use only. This is general information, not medical advice, so talk with your clinician about what is right for you.

Drysol cost: manufacturer savings card vs. an Rx.com cash coupon

Searches for a Drysol coupon usually turn up two different things. The first is a manufacturer savings card. Drysol is marketed by Person & Covey, and any current savings offer would be posted on that company's own website; we do not link a savings-card page here because those deep links change and break often. Manufacturer cards are generally limited to people with commercial (non-government) insurance, and terms vary, so read the eligibility rules before you count on one. People who are uninsured, or who have Medicare or another government plan, are typically excluded.

The second is a cash discount coupon like the one on this page. An Rx.com cash coupon does not use your insurance, so it works whether you are uninsured, on Medicare, or simply told the manufacturer card was declined at the register. Because Drysol is marketed without an FDA New Drug Application, there is no FDA-approved, AB-rated generic of it that a pharmacist could automatically substitute. Unbranded aluminum chloride hexahydrate listings do appear in pharmacy databases, but whether any of them is an appropriate stand-in for your prescription is a question for your pharmacist and prescriber, not something to assume. You cannot use a cash coupon and your insurance on the same fill, so compare both and use whichever is lower. Prices vary by pharmacy and by strength, so enter your ZIP above to see today's price.

Drysol alternatives and related options

If Drysol is not a fit, several other options are used for excessive sweating. Your clinician decides what is appropriate for your situation.

  • Aluminum chloride hexahydrate — the same active ingredient, sold in unbranded listings; ask your pharmacist what is actually stocked and whether it fits your prescription.
  • Hypercare — another prescription aluminum chloride hexahydrate solution, labeled 15% w/v in its package insert.
  • Xerac AC — a lower, 6.25% strength of the same ingredient. It is also a prescription product, not an over-the-counter one.
  • Certain Dri Clinical Strength — an over-the-counter antiperspirant whose Drug Facts label lists aluminum chloride 15%, despite the "prescription protection" wording on the package. The separate, plain Certain Dri Roll-On is labeled aluminum chloride 12%.
  • Qbrexza — a medicated cloth containing glycopyrronium, a different approach applied to the skin.
  • Glycopyrrolate and oxybutynin chloride — oral anticholinergic medicines sometimes used when topical treatment is not enough.

Beyond medication, iontophoresis, botulinum toxin injections, and surgery are options clinicians consider when a topical antiperspirant like Drysol does not control symptoms.

Drysol safety and how to use it with less irritation

Drysol has no boxed warning. The solution is made with absolute (anhydrous) alcohol and is flammable, so keep it away from fire, flame, and smoking, and let it dry completely before dressing or going to bed. Do not apply it to broken, irritated, or freshly shaved or waxed skin; wait at least 24 to 48 hours after shaving. Keep it away from your eyes and other mucous membranes. It is not for use as a deodorant, and not for the face unless your clinician directs it.

The most common side effects are stinging, burning, itching, prickling, and skin irritation. You can reduce irritation by applying it only to completely dry skin at bedtime, washing it off in the morning, and not covering the area with plastic wrap unless your clinician tells you to. Aluminum chloride can damage or discolor clothing and metal. It should not be used by anyone allergic to aluminum chloride. Stop using it and contact your clinician if you develop severe irritation, a rash, or signs of infection. This is a summary, not medical advice; read the label that comes with your bottle and ask your pharmacist or clinician with any questions.

Sources & accuracy

This Drysol information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Drysol on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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