Exemestane Coupons & Prices

Looking for an exemestane coupon? Exemestane is the generic form of Aromasin, an aromatase inhibitor taken once daily by postmenopausal women with hormone-receptor-positive breast cancer. A generic version is available in the US, but the cash price you pay can differ a lot from one pharmacy to the next, even between stores in the same town. Enter your ZIP above to see today's exemestane price near you with a free Rx.com coupon, which compares prices across more than 60,000 pharmacies so you can see where your prescription is cheapest before you fill it.

What is exemestane and how does it work?

Exemestane is the generic name for the brand drug Aromasin. It belongs to a class of medicines called aromatase inhibitors, and it is a steroidal, irreversible one, which means it permanently blocks the aromatase enzyme it binds to. After menopause, the body makes most of its estrogen through that enzyme. Many breast cancers grow in response to estrogen, so lowering estrogen levels can help slow or stop that growth. Exemestane is a hormonal antineoplastic agent and is not a controlled substance.

The FDA has approved exemestane tablets for postmenopausal women in two settings. The first is adjuvant treatment of estrogen-receptor-positive early breast cancer in women who have already taken two to three years of tamoxifen and switch to exemestane to complete a total of five consecutive years of hormonal therapy. The second is treatment of advanced breast cancer in postmenopausal women whose disease has progressed after tamoxifen. Exemestane is not indicated for breast cancer in premenopausal women. It is taken once daily after a meal.

What exemestane costs without insurance, and how to pay less

Because a generic is on the market, exemestane is usually far less expensive than it was as a brand-only medicine, but there is no single price. Cash prices are set pharmacy by pharmacy, and the spread between the cheapest and most expensive pharmacy near you can be surprisingly wide for the exact same tablet and quantity. That is why comparing is worth the two minutes. Enter your ZIP above to see today's price at pharmacies near you, then show the free Rx.com coupon at the counter. The coupon is for people paying cash and cannot be combined with insurance, though it is always worth checking which route is lower for you.

If you are prescribed brand-name Aromasin, Pfizer runs patient support through its Pfizer Oncology Together and Pfizer RxPathways programs, listed on Pfizer's official websites. Eligibility rules and terms vary, and these programs typically exclude people with government coverage such as Medicare or Medicaid, so check the current terms directly with the program. Filling a 90-day supply instead of 30 days, and asking your pharmacist whether a different manufacturer's generic is stocked, can also change what you pay.

Exemestane vs. anastrozole and letrozole

All three are aromatase inhibitors used in postmenopausal women with hormone-receptor-positive breast cancer, and all three are available as low-cost generics. The main difference is chemical structure. Exemestane is steroidal and binds the aromatase enzyme irreversibly, while anastrozole (brand Arimidex) and letrozole (brand Femara) are nonsteroidal and block the enzyme reversibly. That structural difference is why exemestane is sometimes used after a nonsteroidal aromatase inhibitor has stopped working.

A different option is tamoxifen, which is not an aromatase inhibitor at all. It blocks estrogen receptors rather than lowering estrogen production, and it can be used in premenopausal as well as postmenopausal women. In the approved adjuvant setting, exemestane is specifically the drug women switch to after two to three years of tamoxifen. Which of these is right for you is a decision for your oncologist; if you are switching, it is worth comparing prices on each, since generic pricing varies independently at every pharmacy.

Safety, side effects, and what to tell your doctor

Exemestane has no boxed warning. It should not be used by anyone with a known hypersensitivity to exemestane, and it is not indicated for premenopausal women. Two label warnings matter most over time. Bone mineral density can decrease with continued use, raising the risk of osteoporosis and fracture, so your doctor may check your bone density and your baseline vitamin D level and recommend a supplement if you are deficient. The second is embryo-fetal toxicity: exemestane can harm an unborn baby. The label calls for a negative pregnancy test within 7 days before starting, effective contraception during treatment and for 1 month after the final dose, and no breastfeeding during treatment or for 1 month after.

In early breast cancer, the most common side effects reported in 10 percent or more of women were hot flushes, fatigue, joint pain, headache, trouble sleeping, and increased sweating. In advanced disease, the most common were hot flushes, nausea, and fatigue. Tell your doctor about all your other medicines: strong CYP3A4 inducers such as rifampicin or phenytoin require the daily dose to be increased from 25 mg to 50 mg. This page is general information, not medical advice. Talk with your doctor or pharmacist about your own situation.