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Fosfomycin Tromethamine

Fosfomycin Tromethamine 3GM

Women's Health Care
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What is Fosfomycin Tromethamine?

Fosfomycin tromethamine is a broad-spectrum antibiotic used primarily for the treatment of uncomplicated urinary tract infections caused by susceptible strains of bacteria. It works by inhibiting the synthesis of bacterial cell walls, effectively leading to bacterial cell death. Administered orally, this drug is known for its singular dose regimen, which enhances patient compliance.

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What is Fosfomycin Tromethamine ?

Fosfomycin tromethamine is a broad-spectrum antibiotic used primarily for the treatment of uncomplicated urinary tract infections caused by susceptible strains of bacteria. It works by inhibiting the synthesis of bacterial cell walls, effectively leading to bacterial cell death. Administered orally, this drug is known for its singular dose regimen, which enhances patient compliance.
  • Severe and watery diarrhea that may contain blood.
  • Severe stomach pain.
  • Vision changes.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Yellowing of your skin or the whites of your eyes.
  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease or diarrhea.
  • This medicine may cause diarrhea, and in some cases it can be severe. It may occur 2 months or more after you stop taking this medicine. Do not take any medicine to treat diarrhea without first checking with your doctor. If you have any questions or if mild diarrhea continues or gets worse, check with your doctor.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Vision changes.
  • Yellowing of your skin or the whites of your eyes.
What is fosfomycin tromethamine used to treat?
Fosfomycin tromethamine is FDA-approved to treat uncomplicated urinary tract infections (acute cystitis) in women caused by susceptible strains of Escherichia coli and Enterococcus faecalis. It is not approved for kidney infections (pyelonephritis) or infections outside the bladder.
How long does it take for fosfomycin (Monurol) to work for a UTI?
Fosfomycin is given as a single dose, and symptoms often begin to improve within a few days as the medication works in the bladder. If your symptoms do not improve, get worse, or come back, contact your provider, since you may need further evaluation or a different treatment.
Do you take fosfomycin tromethamine as a single dose or multiple doses?
For uncomplicated acute cystitis, fosfomycin is taken as a single 3-gram dose dissolved in water. Only one dose should be used per episode; repeated daily dosing does not improve outcomes and increases the chance of side effects. Any different regimen should be directed by your provider.
What are the most common side effects of fosfomycin tromethamine?
The most common side effects are diarrhea, headache, nausea, and vaginitis. Like other antibiotics, it can also cause C. difficile-associated diarrhea and, rarely, serious allergic reactions. Contact your provider if you have severe or persistent diarrhea or signs of an allergic reaction.
Is fosfomycin tromethamine safe during pregnancy?
Whether fosfomycin is appropriate during pregnancy is a decision for your healthcare provider, who will weigh the benefits and risks for your situation. Always tell your provider if you are pregnant or may be pregnant before starting any antibiotic. This is not medical advice.
How much does Fosfomycin Tromethamine cost without insurance?
The price of Fosfomycin Tromethamine without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 67% off retail prices with a free Rx.com coupon.
What are the common side effects of Fosfomycin Tromethamine?
Common side effects of Fosfomycin Tromethamine may include: Severe and watery diarrhea that may contain blood., Severe stomach pain., Vision changes., Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Yellowing of your skin or the whites of your eyes.. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Fosfomycin Tromethamine?
Generic versions may be available for Fosfomycin Tromethamine. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Fosfomycin Tromethamine on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Fosfomycin Tromethamine?
The cheapest pharmacy for Fosfomycin Tromethamine depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Fosfomycin Tromethamine near you.

Fosfomycin Tromethamine Coupons & Prices

Fosfomycin Tromethamine 3GM

Women's Health Care
Licensed US providers · Online visit in minutes
Fosfomycin Tromethamine Packet — prescription drug image
Prescription
Fosfomycin Tromethamine 3gm (1)
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Looking for a fosfomycin tromethamine coupon? Fosfomycin tromethamine is the generic form of the antibiotic Monurol, taken as a single 3-gram oral dose dissolved in water to treat uncomplicated urinary tract infections (acute cystitis) in women. Because it is a generic, cash prices are already relatively low, but they can still vary widely from one pharmacy to the next. Enter your ZIP above to see today's price and compare across more than 60,000 pharmacies with a free Rx.com discount coupon.

What is fosfomycin tromethamine and how does it work?

Fosfomycin tromethamine is an antibiotic in the phosphonic acid derivative class. It is bactericidal, meaning it kills bacteria by blocking an early step in bacterial cell-wall synthesis. It is FDA-approved only for the treatment of uncomplicated urinary tract infections (acute cystitis) in women caused by susceptible strains of Escherichia coli and Enterococcus faecalis.

A key feature is that it is given as a single 3-gram dose dissolved in water, rather than a multi-day course. It is sold under the brand name Monurol, and the generic is widely available. It is not indicated for kidney infections (pyelonephritis) or perinephric abscess. Some clinicians use it off-label for harder-to-treat or resistant infections, but any such use should be directed by your provider.

Fosfomycin tromethamine cost and savings without insurance

Fosfomycin tromethamine is available as a generic, which usually keeps the cash price lower than a brand-name equivalent. Even so, the single-dose packet can cost more than many people expect, and the price for the exact same medication often differs significantly between pharmacies in the same town. That is why comparing prices matters.

Rx.com compares live cash prices across more than 60,000 pharmacies and gives you a free discount coupon you can use with or without insurance. To see what fosfomycin tromethamine costs near you today, enter your ZIP above. If your provider prescribed the brand, you can also check Monurol pricing and compare it to the generic.

Alternatives and how fosfomycin compares

Fosfomycin is one of several first-line and alternative options for uncomplicated UTIs. Your provider chooses based on your history, local resistance patterns, allergies, and kidney function. Other commonly prescribed UTI antibiotics include:

  • nitrofurantoin — a common first-line choice for uncomplicated cystitis
  • trimethoprim-sulfamethoxazole — another widely used first-line option
  • ciprofloxacin — a fluoroquinolone typically reserved for certain cases
  • cephalexin — a cephalosporin sometimes used for UTIs

The main convenience of fosfomycin is single-dose treatment. This is not medical advice; talk with your provider or pharmacist about which antibiotic is right for you.

Safety and side effects

Fosfomycin tromethamine has no boxed warning. Only a single dose should be used per episode of acute cystitis. Taking repeated daily doses does not improve outcomes and can increase side effects. It is not effective for kidney infections or infections outside the bladder. The most common side effects are diarrhea, headache, nausea, and vaginitis.

Like other antibiotics, it can cause Clostridioides difficile-associated diarrhea, which can range in severity up to serious colitis and may begin during treatment or even weeks to months afterward. Allergic reactions, including anaphylaxis, have been reported. The medication metoclopramide can lower fosfomycin levels and reduce its effect. Antibiotics do not treat viral infections. This is general information, not medical advice; tell your provider about all medicines you take and about any pregnancy or possible pregnancy, and seek care for severe or persistent diarrhea.

Sources & accuracy

This Fosfomycin Tromethamine information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Fosfomycin Tromethamine on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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