Ibsrela
Ibsrela 60 Tablets
What is Ibsrela?
Ibsrela is a medication used to treat irritable bowel syndrome with constipation (IBS-C) in adults. It helps relieve symptoms like stomach pain and difficulty passing stools.Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Severe diarrhea
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease or other stomach or bowel problems.
- This medicine may cause severe diarrhea.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Prescription savings · · · ·
What is Ibsrela ?
Ibsrela is a medication used to treat irritable bowel syndrome with constipation (IBS-C) in adults. It helps relieve symptoms like stomach pain and difficulty passing stools.- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Severe diarrhea
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease or other stomach or bowel problems.
- This medicine may cause severe diarrhea.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Ibsrela Coupons & Prices
Ibsrela 60 Tablets
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Looking for an Ibsrela coupon? Ibsrela (tenapanor) is a brand-name prescription tablet from Ardelyx used to treat irritable bowel syndrome with constipation (IBS-C) in adults. As a brand-name medicine with no generic, the cash price can run several hundred dollars for a one-month supply without insurance, though it varies by pharmacy. A free Rx.com Ibsrela coupon lets you compare cash prices at more than 60,000 U.S. pharmacies and show the coupon at the counter — no membership, no signup, and nothing to pay Rx.com. Enter your ZIP code above to see today's lowest Ibsrela price near you.
What is Ibsrela (tenapanor) and how does it work?
Ibsrela is the brand name for tenapanor, a prescription medicine that works in the gut to reduce the absorption of sodium. This increases the amount of water in the intestine, which softens stool and helps it pass more easily, while also helping to ease abdominal pain.
Doctors prescribe Ibsrela for adults with irritable bowel syndrome with constipation (IBS-C). It is usually taken as a tablet twice a day, just before breakfast and dinner.
How much does Ibsrela cost without insurance?
Ibsrela is a brand-name drug with no generic version available, which is the main reason the cash price is high. Prices also vary by pharmacy and location — the same prescription can differ by a wide margin between two pharmacies in the same town. That price gap is exactly why comparing pharmacies with a coupon matters. Enter your ZIP code above to see live cash prices near you and pull up a free coupon for the lowest one.
Ibsrela coupon vs. the manufacturer savings card
Ardelyx offers an Ibsrela savings program, but manufacturer copay cards are generally limited to patients with commercial (private) insurance and typically exclude people with Medicare, Medicaid, or no insurance. If you are paying cash or your plan does not cover Ibsrela, a free Rx.com discount coupon is often the more useful option because anyone can use it regardless of insurance status. Compare the manufacturer terms against the Rx.com cash price above to see which is lower for you.
Ibsrela vs. Linzess and Trulance
Ibsrela is one of a few prescription options for IBS-C. Linzess (linaclotide) and Trulance (plecanatide) are GC-C agonists that work through a different mechanism than tenapanor. Each has different dosing, side effects, and cost, so the right choice is a decision for you and your doctor. If you are prescribed a different IBS-C medicine, you can pull up a free Rx.com coupon for it the same way you would for Ibsrela.
Important Ibsrela safety information
Ibsrela carries a boxed warning: it must not be used in children under 6, and it should be avoided in children 6 to under 12, because of the risk of serious dehydration. The most common side effect in adults is diarrhea, which can sometimes be severe — stop taking Ibsrela and call your doctor if you get severe diarrhea. This information is educational and is not a substitute for medical advice — always follow your doctor and pharmacist's instructions.
This Ibsrela information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Ibsrela on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.