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Inderal Xl Capsule Extended Release 24 Hour — prescription drug image

Inderal Xl

Inderal XL 80MG

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What is Inderal Xl?

Inderal XL is a brand name for the extended-release formulation of propranolol hydrochloride, a non-selective beta blocker that is primarily used to treat hypertension and prevent angina. It works by reducing the workload on the heart and slowing the heart rate, thereby lowering blood pressure and improving heart efficiency. Inderal XL's extended-release formulation allows for once-daily dosing, providing consistent therapeutic levels throughout the day.

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What is Inderal Xl ?

Inderal XL is a brand name for the extended-release formulation of propranolol hydrochloride, a non-selective beta blocker that is primarily used to treat hypertension and prevent angina. It works by reducing the workload on the heart and slowing the heart rate, thereby lowering blood pressure and improving heart efficiency. Inderal XL's extended-release formulation allows for once-daily dosing, providing consistent therapeutic levels throughout the day.
  • Slow, fast, pounding, or uneven heartbeat
  • Lightheadedness, dizziness, or fainting
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Shaking, trembling, sweating, hunger, confusion
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, or red skin rash
  • Change or loss of consciousness, seizures
  • Chest pain, trouble breathing
  • Unusual tiredness or weakness
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, angina (chest pain), heart failure, breathing problems, diabetes, glaucoma, an overactive thyroid, or any medical conditions (including colds, stress, infection). Tell your doctor if you have Wolff-Parkinson-White syndrome or a history of severe allergic reactions. Tell your doctor if you are fasting (including surgery, not eating regularly, vomiting).
  • This medicine may cause the following problems:Increased risk of heart or blood vessel problems, including a slow heart beat or low blood pressureWorsening of chest pain, heart attack (if treatment is stopped suddenly)Heart failureIncreased risk for hypoglycemia (low blood sugar) and cover up the symptoms of low blood sugar (including fast heartbeat)An increased risk of stroke in children with PHACE syndrome (severe blood vessel problems in the brain)
  • Do not stop using this medicine suddenly without asking your doctor, or you could develop life-threatening heart problems.
  • This medicine may make you dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Tell any doctor or dentist who treats you that you are using this medicine.
  • This medicine may cause erectile dysfunction in some males. If you have questions about this, talk to your doctor.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is Inderal XL used for?
Inderal XL is FDA-approved for one use only: treating hypertension (high blood pressure). Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, mainly strokes and heart attacks. Other propranolol products, such as Inderal LA, have additional approved uses, but the Inderal XL label is limited to high blood pressure.
Why do you have to take Inderal XL at bedtime?
Inderal XL is a chronotherapeutic extended-release capsule, meaning it is designed to release the medicine on a delayed schedule after you swallow it. Because of that design, the label directs you to take it once daily at bedtime. The label also says to be consistent about food: take it either always on an empty stomach or always with food, since switching affects how much you absorb.
What is the difference between Inderal XL and Inderal LA?
Both are extended-release propranolol hydrochloride capsules, but their FDA labels differ. Inderal XL is approved only for high blood pressure and is taken at bedtime. Inderal LA is approved for high blood pressure plus angina, atrial fibrillation, migraine prevention, essential tremor, hypertrophic subaortic stenosis, and use after a heart attack. They are not automatically interchangeable, so do not switch without your prescriber's direction.
Is there a generic for Inderal XL?
No. There is no substitutable generic version of Inderal XL extended-release capsules, so you are filling a brand-name product. Generic propranolol does exist in other forms, such as immediate-release tablets, but those are different products with different dosing and are not automatic substitutions. If cost is a problem, ask your prescriber whether another form of propranolol or a different beta blocker would work for you, and compare cash prices with a coupon by entering your ZIP code above.
What happens if you stop taking Inderal XL suddenly?
Stopping a beta blocker abruptly can be dangerous. Abrupt discontinuation has caused worsening angina (chest pain) and heart attacks, particularly in people with coronary artery disease. If you need to stop, your doctor will usually taper the dose over about one to two weeks and watch you closely. Do not run out of your prescription or quit on your own; talk to your provider first.
How much does Inderal Xl cost without insurance?
The price of Inderal Xl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Inderal Xl?
Common side effects of Inderal Xl may include: Slow, fast, pounding, or uneven heartbeat, Lightheadedness, dizziness, or fainting, Rapid weight gain, swelling in your hands, ankles, or feet, Shaking, trembling, sweating, hunger, confusion, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Inderal Xl?
Generic versions may be available for Inderal Xl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Inderal Xl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Inderal Xl?
The cheapest pharmacy for Inderal Xl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Inderal Xl near you.

Inderal Xl Coupons & Prices

Inderal XL 80MG

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Inderal XL (propranolol hydrochloride extended-release capsules) is a brand-name beta blocker taken once daily at bedtime to lower high blood pressure. There is no generic version of Inderal XL, so the cash price at the pharmacy counter can be a real burden. An Inderal XL coupon from Rx.com is a free cash-discount card you can show at the pharmacy instead of paying the pharmacy's usual cash price. Enter your ZIP code above to see today's price for your strength and quantity at pharmacies near you, and bring the coupon with you when you fill it.

What Is Inderal XL and How Does It Work?

Inderal XL is an extended-release capsule form of propranolol hydrochloride, a nonselective beta-adrenergic blocker (beta blocker). Beta blockers ease the workload on your heart, which helps bring blood pressure down. Inderal XL has only one FDA-approved use: the treatment of hypertension (high blood pressure). Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and heart attacks.

Inderal XL uses a chronotherapeutic release design, which is why it is taken once daily at bedtime rather than in the morning. The usual starting dose is 80 mg at bedtime and may be increased to 120 mg. One practical tip from the label: take it consistently either always on an empty stomach or always with food, since switching back and forth can change how much drug your body absorbs. Your prescriber decides your dose and schedule; this page is general information, not medical advice.

Inderal XL Cost: Manufacturer Savings vs. an Rx.com Cash Coupon

Inderal XL is a brand-only product with no generic equivalent, so what you pay depends heavily on your coverage and on which pharmacy you use. Prices vary quite a bit from pharmacy to pharmacy, so it is worth comparing before you fill. Enter your ZIP above to see today's price near you.

Manufacturer savings cards for brand drugs are generally limited to people with commercial (non-government) insurance, and terms, eligibility, and expiration dates vary. They typically exclude people with Medicare, Medicaid, TRICARE, or other government coverage, and they usually do not help the uninsured. If you want to check whether a savings offer or patient-assistance program is currently running for Inderal XL, look on the manufacturer's own website (ANI Pharmaceuticals) rather than trusting a third-party link. The Rx.com cash coupon works differently: it is a cash-discount card, not insurance, so it can be used if you are uninsured, if you are on Medicare and would rather pay cash, or if a manufacturer card is declined. You cannot combine a cash coupon with your insurance on the same fill, so ask the pharmacist to run it both ways and take the lower price.

Inderal XL vs. Inderal LA, Propranolol, and Other Beta Blockers

Several propranolol products exist, and they are not interchangeable on paper even though they share the same active ingredient. Inderal LA is a different extended-release propranolol product with a broader label: in addition to hypertension, it is approved for angina, atrial fibrillation, migraine prevention, essential tremor, hypertrophic subaortic stenosis, and use after a heart attack. InnoPran XL is another extended-release propranolol capsule. Immediate-release propranolol is taken more than once a day and adds pheochromocytoma to its label. Hemangeol is a propranolol oral solution. The immediate-release Inderal brand itself is no longer marketed in the US, though propranolol immediate-release is still available. Note that propranolol is also commonly prescribed off-label for situational or performance anxiety, thyroid-related symptoms, and akathisia; those uses are not on the Inderal XL label, and off-label prescribing is your doctor's call, not something we recommend.

If cost is the sticking point, ask your prescriber whether a different beta blocker with an available generic would work for your blood pressure. Common alternatives include metoprolol succinate (the extended-release form, sold as Toprol-XL), atenolol, and carvedilol. These are different medicines, not substitutes you can swap on your own, and only your prescriber can decide whether a switch makes sense for you.

Safety, Side Effects, and What to Watch For

Inderal XL does not carry a boxed warning. The most important safety point is this: do not stop taking it abruptly. Suddenly stopping a beta blocker has caused worsening chest pain and heart attacks, especially in people with coronary artery disease. If you and your doctor decide to stop, the dose is usually tapered over about one to two weeks. Inderal XL should not be used by people with cardiogenic shock or decompensated heart failure, slow heart rate (sinus bradycardia), sick sinus syndrome, heart block greater than first degree (without a pacemaker), bronchial asthma, or a known allergy to propranolol.

Other things to know: propranolol can slow the heart or cause heart block, and that risk goes up if you also take a calcium channel blocker or digoxin. It can worsen heart failure and can trigger bronchospasm in people with bronchospastic lung disease. It masks the racing-heart warning sign of low blood sugar and may cause severe low blood sugar in people with diabetes and in children, so use caution. It also masks the symptoms of an overactive thyroid, and stopping it abruptly can trigger thyroid storm. People taking beta blockers may respond less well to usual doses of epinephrine used to treat a severe allergic reaction. Use caution with liver problems, and note that propranolol passes into breast milk. Common side effects include tiredness, dizziness, a slow heart rate, cold hands and feet, and sleep disturbances. Tell your provider about all your medicines and conditions, and call them with any questions about your treatment.

Sources & accuracy

This Inderal Xl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Inderal Xl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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