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Insulin Glargine-Yfgn Pen — prescription drug image

Insulin Glargine-Yfgn

Insulin Glargine-yfgn 3ML of 100UNIT/ML

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What is Insulin Glargine-Yfgn?

Insulin Glargine-yfgn is a prescription long-acting insulin used to improve blood sugar control in adults and children with type 1 diabetes and adults with type 2 diabetes. It provides steady, 24-hour blood sugar control with a once-daily injection and is available as a lower-cost biosimilar to insulin glargine products such as Semglee®.

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What is Insulin Glargine-Yfgn ?

Insulin Glargine-yfgn is a prescription long-acting insulin used to improve blood sugar control in adults and children with type 1 diabetes and adults with type 2 diabetes. It provides steady, 24-hour blood sugar control with a once-daily injection and is available as a lower-cost biosimilar to insulin glargine products such as Semglee®.

  • Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion
  • Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing, tiredness
  • Blurred vision or changes in vision, severe headache, slow heartbeat, dizziness
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Dry mouth, increased thirst, muscle cramps, nausea, vomiting, uneven heartbeat
  • Fever, chills, cough, stuffy or runny nose, sore throat, body aches
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • This medicine may cause the following problems:Low blood sugarFluid retention or heart failure (when used with thiazolidinedione [TZD] medicine)
  • Never share insulin pens, needles, or cartridges with anyone. Sharing these can pass hepatitis viruses, HIV, or other illnesses from one person to another.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease (including heart failure), or ketoacidosis (high ketones and acid in the blood).
  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
Is insulin glargine-yfgn (Semglee) the same as Lantus?
It is not the exact same product, but it is very closely matched. Insulin glargine-yfgn (sold as Semglee) is FDA-approved as biosimilar to and interchangeable with insulin glargine (Lantus). This means it was shown to be highly similar to Lantus with no clinically meaningful differences, and it can be substituted for Lantus. Always follow the guidance of your prescriber and pharmacist.
How much does insulin glargine-yfgn cost without insurance?
The cash price without insurance varies widely from pharmacy to pharmacy. Because insulin glargine-yfgn is available as an unbranded biosimilar, it is often lower cost than brand insulin, but the only way to know today's price near you is to compare. Enter your ZIP above to see current prices at pharmacies in your area and get a coupon.
Can a pharmacist substitute Semglee for Lantus without asking my doctor?
Because insulin glargine-yfgn (Semglee) is FDA-approved as interchangeable with insulin glargine (Lantus), a pharmacist may be able to substitute it without a new prescription from your doctor, similar to how a generic can be swapped for a brand. Rules can vary by state, so ask your pharmacist how it works where you live.
What is the difference between Semglee and insulin glargine-yfgn (unbranded)?
They are the same medicine. Semglee is the brand name, and insulin glargine-yfgn is the same product sold under its unbranded (generic-style) name. The unbranded version is often offered at a lower cash price. Comparing both, along with any manufacturer savings program, can help you find the best price.
How do you inject insulin glargine-yfgn?
Insulin glargine-yfgn is given as a once-daily injection under the skin (subcutaneously). It should never be given into a vein (IV) or used in an insulin pump, and it should not be mixed or diluted with any other insulin or solution. Never share a pen or needle with another person. Your provider or pharmacist will show you the correct injection technique and rotation of injection sites.
How much does Insulin Glargine-yfgn 3ML of 100UNIT/ML cost without insurance?
The price of Insulin Glargine-yfgn 3ML of 100UNIT/ML without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Insulin Glargine-yfgn 3ML of 100UNIT/ML?
Common side effects of Insulin Glargine-yfgn 3ML of 100UNIT/ML may include: Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion, Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing, tiredness, Blurred vision or changes in vision, severe headache, slow heartbeat, dizziness, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Dry mouth, increased thirst, muscle cramps, nausea, vomiting, uneven heartbeat. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Insulin Glargine-yfgn 3ML of 100UNIT/ML?
Generic versions may be available for Insulin Glargine-yfgn 3ML of 100UNIT/ML. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Insulin Glargine-yfgn 3ML of 100UNIT/ML on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Insulin Glargine-yfgn 3ML of 100UNIT/ML?
The cheapest pharmacy for Insulin Glargine-yfgn 3ML of 100UNIT/ML depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Insulin Glargine-yfgn 3ML of 100UNIT/ML near you.

Insulin Glargine-Yfgn Coupons & Prices

Insulin Glargine-yfgn 3ML of 100UNIT/ML

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Insulin Glargine-Yfgn Pen — prescription drug image
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Insulin Glargine-Yfgn prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
3ml of 100unit/ml · Pen 3 $23.00

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for an insulin glargine-yfgn coupon? Rx.com helps you compare cash prices for insulin glargine-yfgn (the unbranded version of Semglee) at more than 60,000 pharmacies so you can find a low price near you. This once-daily long-acting insulin is FDA-approved as biosimilar to and interchangeable with insulin glargine (Lantus), and because the cash price can vary widely from one pharmacy to the next, comparing before you fill can make a real difference. Enter your ZIP above to see today's price at pharmacies near you.

What is insulin glargine-yfgn and how does it work?

Insulin glargine-yfgn is a long-acting human insulin analog, also called a basal insulin. It is sold under the brand name Semglee and as an unbranded version. It is used to improve blood sugar (glycemic) control in adults and children with type 1 diabetes and in adults with type 2 diabetes. As a once-daily long-acting insulin, it provides a steady, background level of insulin throughout the day and night.

Insulin glargine-yfgn is FDA-approved as both a biosimilar to and interchangeable with insulin glargine (Lantus) — in fact, it was the first interchangeable biosimilar insulin approved in the United States. It is not recommended for treating diabetic ketoacidosis, and it is not for use in an insulin pump or given into a vein.

Insulin glargine-yfgn cost and savings without insurance

Because insulin glargine-yfgn is available as an unbranded (generic-style) biosimilar, it is often a lower-cost way to get insulin glargine therapy. Even so, the cash price without insurance can vary a lot depending on which pharmacy you use, which is why it pays to compare. Rx.com checks prices across more than 60,000 pharmacies so you can see what it actually costs near you today — just enter your ZIP above to see the current price and print or show a coupon at the counter.

There is also a manufacturer savings program for Semglee for eligible patients. Terms, eligibility, and any limits are set by the program and can change, so check the official page for details at the Semglee savings site. A manufacturer card and a cash coupon can't be combined, so it's worth comparing both to see which gives you the better price.

Insulin glargine-yfgn vs. other long-acting insulins

Insulin glargine-yfgn is one of several long-acting basal insulins. Its closest match is insulin glargine itself — it is interchangeable with Lantus and is the same active ingredient found in other insulin glargine products such as Basaglar and the higher-concentration Toujeo. You can also compare the unbranded product with the branded Semglee and the general insulin glargine listing.

Other long-acting insulins work similarly but use different active ingredients, including insulin detemir (Levemir / insulin detemir) and insulin degludec (Tresiba). These are not interchangeable with insulin glargine-yfgn. Which insulin is right for you is a decision for you and your prescriber — this comparison is for pricing and general information only, not medical advice.

Safety and what to know before using

Hypoglycemia (low blood sugar) is the most common and potentially serious side effect of insulin glargine-yfgn. Your risk can go up with changes to your insulin regimen, meal patterns, or physical activity, and when it is used with other glucose-lowering medicines. Some medicines, such as ACE inhibitors, can increase the risk of low blood sugar, and beta-blockers can mask the warning signs. Your provider may need to adjust your dose if you have kidney or liver problems, and blood potassium should be monitored because low potassium (hypokalemia) can occur.

A few important cautions: never share pens or needles with anyone else, even if the needle is changed, because of the risk of passing bloodborne infections. Do not dilute or mix insulin glargine-yfgn with any other insulin or solution, and do not use it in an IV or an insulin pump. Severe, life-threatening allergic reactions (anaphylaxis) can happen, and fluid retention or heart failure can occur if it is taken with thiazolidinediones (TZDs). This is general information, not medical advice — talk with your doctor or pharmacist about your specific situation and any questions about your diabetes care.

Sources & accuracy

This Insulin Glargine-Yfgn information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Insulin Glargine-Yfgn on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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