Kyleena
Kyleena 1 Intrauterine Device
What is Kyleena?
Kyleena is used to prevent pregnancy. There is not a generic version currently available for Kyleena. On average, Kyleena is priced at approximately $957 for a supply of 1, 19.5 mg intrauterine device. You can use our free Singlecare savings card to receive a Kyleena discount of up to 80% at a local pharmacy that participates with Singlecare.Side Effects
- Unusual bleeding, bruising, or weakness
- Vaginal discharge that has a bad smell, fever, chills, sores on your genitals
- Severe headache, vision changes
Warnings
- If you have the Skyla® or Kyleena®, tell your doctor before you have an MRI test.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- This IUD will not protect you from HIV/AIDS or other sexually transmitted diseases.
- Tell your doctor if you have had any problems, infections, or other conditions that affected your reproductive system. There are many problems that could make an IUD a bad choice for you, including if you have fibroids, unexplained bleeding, a uterus that has an unusual shape, a recent infection, a history of pelvic inflammatory disease, an abnormal Pap test, ectopic pregnancy, cancer or suspected cancer, or an existing IUD.
- Tell your doctor if you are breastfeeding, or if you had a baby, miscarriage, or abortion in the past 3 months. Tell your doctor if you have liver disease (including tumor or cancer), heart disease, breast cancer, heart or blood circulation problems (including a slow heartbeat), migraine, high blood pressure, seizures, or a history of fainting, heart valve problems, blood clotting problems, stroke, or heart attack. Tell your doctor if you have problems with your immune system or have had surgery on your female organs (especially fallopian tubes).
Prescription savings · · · ·
What is Kyleena ?
Kyleena is used to prevent pregnancy. There is not a generic version currently available for Kyleena. On average, Kyleena is priced at approximately $957 for a supply of 1, 19.5 mg intrauterine device. You can use our free Singlecare savings card to receive a Kyleena discount of up to 80% at a local pharmacy that participates with Singlecare.- Unusual bleeding, bruising, or weakness
- Vaginal discharge that has a bad smell, fever, chills, sores on your genitals
- Severe headache, vision changes
- Yellow skin or eyes
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Bloating, stomach or pelvic pain, spasm, tenderness, or cramping that is sudden or severe
- Chest pain, problems with speech or walking, numbness or weakness in your arm or leg or on one side of your body
- Heavy bleeding from your vagina
- Pain during sex, or if your partner feels the hard plastic of the IUD during sex
- If you have the Skyla® or Kyleena®, tell your doctor before you have an MRI test.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- This IUD will not protect you from HIV/AIDS or other sexually transmitted diseases.
- Tell your doctor if you have had any problems, infections, or other conditions that affected your reproductive system. There are many problems that could make an IUD a bad choice for you, including if you have fibroids, unexplained bleeding, a uterus that has an unusual shape, a recent infection, a history of pelvic inflammatory disease, an abnormal Pap test, ectopic pregnancy, cancer or suspected cancer, or an existing IUD.
- Tell your doctor if you are breastfeeding, or if you had a baby, miscarriage, or abortion in the past 3 months. Tell your doctor if you have liver disease (including tumor or cancer), heart disease, breast cancer, heart or blood circulation problems (including a slow heartbeat), migraine, high blood pressure, seizures, or a history of fainting, heart valve problems, blood clotting problems, stroke, or heart attack. Tell your doctor if you have problems with your immune system or have had surgery on your female organs (especially fallopian tubes).
- There is a small chance that you could get pregnant when using an IUD, just as there is with any birth control. If you get pregnant, your doctor may remove your IUD to lower the risk of miscarriage or other problems.
- This medicine may cause the following problems:Increased risk of ectopic pregnancy (pregnancy outside the uterus)Increased risk of serious infections, including sepsisIncreased risk of pelvic inflammatory disease (PID) or endometritisPerforation (hole in the wall of your uterus), which can damage other organsIncreased risk for ovarian cystsIncreased risk of cancer of the breast, uterus, or cervixIncreased risk of high blood pressure, stroke, heart attack, or clotting problemsJaundice (yellow skin or eyes)
- You might have some spotting and cramping during the first weeks after the IUD has been inserted. These symptoms should decrease or go away within a few weeks up to 6 months.
- You could have less bleeding or even stop having periods by the end of the first year. Call your doctor if you have a change from your regular bleeding pattern after you have had your IUD for awhile, including more bleeding or if you miss a period (and you were having periods even with your IUD).
- An IUD can slip partly or all the way out of your uterus. If this happens, use condoms or another form of birth control, and call your doctor right away.
Kyleena Coupons & Prices
Kyleena 1 Intrauterine Device
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Kyleena prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 1 intrauterine device · Box | 1 | $2,677.13 | $1,237.60 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
Kyleena is a hormonal intrauterine device (IUD) that a clinician places in the uterus to prevent pregnancy for up to 5 years. Because it's a brand-name device with no substitutable generic version, cost depends heavily on your insurance coverage and where it's placed. If you're paying out of pocket for the device itself or for related visit costs, a Kyleena coupon from Rx.com can help you compare pharmacy and clinic cash pricing before you commit — enter your ZIP above to see today's price.
What is Kyleena and how does it work?
Kyleena is a small, T-shaped intrauterine system (IUS) that releases the hormone levonorgestrel directly into the uterus. It's FDA-approved to prevent pregnancy for up to 5 years, after which it must be removed or replaced if you want to continue using it. A healthcare provider must insert and remove it; it isn't a product you pick up and use on your own.
Manufacturer savings card vs. an Rx.com cash coupon
Bayer, the maker of Kyleena, offers a co-pay savings program for commercially insured patients — look for the official Kyleena co-pay program on Bayer's site, since terms, eligibility, and amounts vary and can change. Like most manufacturer copay cards, it generally isn't available if you have Medicare, Medicaid, or another government health program, and it doesn't help if you're uninsured. Bayer also runs a separate patient assistance foundation for people who can't otherwise afford the medication and meet income requirements. An Rx.com cash coupon is a different option worth comparing for the device and associated costs, especially if a manufacturer program doesn't apply to your situation.
Because Kyleena is a single manufacturer's device with no AB-rated generic equivalent, there isn't a lower-cost generic version to switch to — the main lever for savings is your insurance benefit and how the clinic bills for the device and insertion visit.
How Kyleena compares to other IUDs
- Mirena – another levonorgestrel IUD from Bayer, but with a higher hormone dose and a longer approved duration than Kyleena.
- Paragard – a non-hormonal, copper IUD that works differently and is also approved for years of use.
- Nexplanon – a hormonal contraceptive implant placed in the arm rather than the uterus.
Your provider can help you decide which option fits your health history, how long you want contraception to last, and whether you prefer a hormonal or non-hormonal method.
Safety information
Kyleena shouldn't be used if you're pregnant or think you might be pregnant, and it's contraindicated in women with current or recent pelvic infection, certain uterine or cervical conditions, or unexplained vaginal bleeding. If pregnancy does occur with Kyleena in place, there's an increased chance it will be ectopic, and the device can, in rare cases, perforate or embed in the uterine wall, most often at the time of insertion. Tell your provider about your full medical history before insertion, and contact them promptly if you have severe pelvic pain, fever, or signs you might be pregnant. This is general information, not medical advice — talk with your provider about whether Kyleena is right for you.
This Kyleena information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Kyleena on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.