Naltrexone Hcl Coupons & Prices

Looking for a naltrexone HCl coupon? Naltrexone hydrochloride is an opioid antagonist available only as a generic tablet (the original brand names, ReVia and Depade, have both been discontinued in the US), and pharmacy cash prices for this generic can vary widely from one drugstore to the next. Rx.com compares prices across more than 60,000 U.S. pharmacies so you can find where naltrexone HCl costs less near you: enter your ZIP code above to see today's price.

What Is Naltrexone HCl and How Does It Work?

Naltrexone hydrochloride is an opioid antagonist, meaning it blocks opioid receptors in the body rather than activating them. It's FDA-approved for two uses: treatment of alcohol dependence, and blocking the effects of opioids as part of a comprehensive treatment program for opioid dependence after a patient has completed detoxification. In both cases, naltrexone is meant to be used alongside counseling or other psychosocial support, not as a standalone treatment, and it isn't intended for patients who are still actively drinking heavily or using opioids or street drugs.

The original brand-name tablets, ReVia and Depade, have both been discontinued in the US, so naltrexone HCl is now available only as a generic tablet. It's a different product from Vivitrol, a distinct extended-release injectable suspension of naltrexone that remains a brand-name product.

Naltrexone HCl Cost Without Insurance

Because naltrexone HCl is generic, the cash price can differ significantly from one pharmacy to the next, even within the same city, so it's worth comparing rather than assuming the first pharmacy you check has the best price. Rx.com checks pricing across more than 60,000 U.S. pharmacies, so you can see which ones offer naltrexone HCl for less: enter your ZIP code above to compare today's prices near you.

Naltrexone vs. Vivitrol and Other Treatment Options

Naltrexone HCl tablets and Vivitrol both contain naltrexone, but they aren't interchangeable: Vivitrol is a monthly extended-release injection given by a provider, while naltrexone HCl is a tablet taken by mouth, and each has its own prescription and dosing schedule.

For alcohol dependence, other FDA-approved medication options include acamprosate and disulfiram, which work differently than naltrexone and may suit patients who can't take an opioid antagonist. For opioid dependence, your provider may also discuss buprenorphine or Suboxone (a buprenorphine/naloxone combination), which work as partial opioid agonists rather than a full antagonist like naltrexone. Naloxone is a related opioid antagonist but is used differently: for emergency reversal of an opioid overdose, not for ongoing treatment.

Naltrexone HCl Safety Information

Naltrexone carries a boxed warning: at doses higher than recommended, it has been associated with liver injury, and it's contraindicated in patients with acute hepatitis or liver failure. Your provider may order liver function tests before and during treatment.

• If you're being treated for opioid dependence, you typically need to be opioid-free for at least 7 to 10 days before starting naltrexone, longer if you were taking methadone; starting too soon can trigger sudden, severe opioid withdrawal.
• Naltrexone will also block the pain-relieving effect of opioid pain medications, so tell any provider treating you for pain that you're taking it.
• After a period on naltrexone, your tolerance to opioids goes down. If you stop naltrexone and later use opioids at doses you were used to before, it can cause a life-threatening overdose.
• Naltrexone itself is not a controlled substance and has no abuse potential.

This is general information, not medical advice. Talk with your provider about whether naltrexone is right for you and how it fits with any other medications you take.