Nisoldipine Er
Nisoldipine ER 17MG
What is Nisoldipine Er?
Nisoldipine ER (extended-release) is a calcium channel blocker used primarily to treat hypertension (high blood pressure) by relaxing the blood vessels, allowing blood to flow more easily. It is typically prescribed for once-daily oral administration to ensure consistent blood levels and effective management of blood pressure throughout the day.Side Effects
- Swelling in your hands, ankles, or feet.
- Rapid weight gain.
- Unusual tiredness or weakness.
Warnings
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have heart disease, liver disease, stomach problems, or aortic stenosis (narrowing of a valve in your heart).
- This medicine may make you dizzy or lightheaded. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Rapid weight gain.
Prescription savings · · · ·
What is Nisoldipine Er ?
Nisoldipine ER (extended-release) is a calcium channel blocker used primarily to treat hypertension (high blood pressure) by relaxing the blood vessels, allowing blood to flow more easily. It is typically prescribed for once-daily oral administration to ensure consistent blood levels and effective management of blood pressure throughout the day.- Swelling in your hands, ankles, or feet.
- Rapid weight gain.
- Unusual tiredness or weakness.
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Chest pain.
- Fast, irregular, or pounding heartbeats.
- Lightheadedness, dizziness, or fainting.
- Warmth or redness in your face, neck, arms, or upper chest.
- Shortness of breath or wheezing.
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have heart disease, liver disease, stomach problems, or aortic stenosis (narrowing of a valve in your heart).
- This medicine may make you dizzy or lightheaded. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Rapid weight gain.
- Shortness of breath or wheezing.
- Swelling in your hands, ankles, or feet.
- Unusual tiredness or weakness.
- Warmth or redness in your face, neck, arms, or upper chest.
Nisoldipine Er Coupons & Prices
Nisoldipine ER 17MG
4 ED medications in one dose
Sildenafil, tadalafil, PT-141 & L-Citrulline · Works in ~15 min · Lasts up to 36 hours
Nisoldipine Er prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 8.5mg · Tablet | 30 | $164.99 | $155.17 |
| 17mg · Tablet | 30 | $296.99 | $193.21 |
| 34mg · Tablet | 30 | $280.95 | $210.25 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
A nisoldipine ER coupon from Rx.com can lower what you pay at the pharmacy counter for generic nisoldipine extended-release tablets, the long-acting calcium channel blocker used to treat high blood pressure. Generic nisoldipine extended-release tablets are available, and they are what most cash-paying patients are dispensed. Cash prices for the same strength and quantity can differ a lot from one pharmacy to the next, even across the street from each other, which is exactly why comparing matters. Rx.com checks prices at more than 60,000 pharmacies nationwide, so enter your ZIP above to see today's price near you and bring the free coupon with you.
What is nisoldipine ER and how does it work?
Nisoldipine extended-release is a dihydropyridine calcium channel blocker. It is FDA-approved to treat hypertension (high blood pressure), either on its own or together with other blood pressure medicines. It works by relaxing and widening your blood vessels, which reduces the resistance your heart has to push against and brings blood pressure down. It is taken once a day as an extended-release tablet.
One important point: nisoldipine is not FDA-approved for angina. Unlike some other medicines in its family, it has no approved use for chest pain. Blood pressure medicines like this one usually do not make you feel different day to day, so keep taking it as prescribed even when you feel fine.
What does nisoldipine ER cost without insurance?
Nisoldipine extended-release is available as a generic, and generics generally do not come with a manufacturer savings card. If you are paying cash, the price you are quoted depends heavily on which pharmacy you walk into. Two pharmacies in the same town can charge very different amounts for the identical strength and count, because each one sets its own cash price. That is why it is worth checking before you fill rather than after.
Rx.com compares prices across more than 60,000 U.S. pharmacies and gives you a free coupon you can show at the counter. There is no membership or signup required, and the coupon is meant for people paying cash rather than using insurance. Enter your ZIP code above to see today's price for your strength and quantity near you, then take the lowest one.
Nisoldipine ER compared with other calcium channel blockers
Nisoldipine ER belongs to the same dihydropyridine family as several other blood pressure medicines your prescriber might consider. These all relax blood vessels, but they differ in how they are dosed, how they are absorbed, and what else they are approved to treat. Related options include:
- amlodipine — the most widely prescribed medicine in this class
- felodipine ER — another once-daily extended-release dihydropyridine
- nifedipine ER — a long-acting form of nifedipine
- isradipine
- nicardipine
Nisoldipine extended-release is also sold under the brand name Sular. Generic nisoldipine extended-release tablets are available, and the generic is what pharmacies typically dispense for cash-paying patients. Whether your pharmacy can substitute a generic for a brand-name prescription depends on your state's substitution laws and on how your prescriber wrote the prescription. Never switch between these medicines on your own. They are not interchangeable, and only your prescriber can decide which one fits your blood pressure, your other conditions, and your other prescriptions.
Safety, side effects, and how to take it
Nisoldipine ER has no boxed warning. It should not be used by anyone with a known hypersensitivity to dihydropyridine calcium channel blockers. A few things to know: rarely, people have had more frequent, longer, or more severe angina, or a heart attack, when starting this medicine or increasing the dose, especially with severe obstructive coronary artery disease (about 1.5% with nisoldipine versus 0.9% with placebo). Blood pressure can also drop too far during the first doses or a dose change, particularly if you take other blood pressure medicines, so your prescriber will want to monitor it. Its safety in heart failure has not been established, and caution is advised, especially alongside a beta-blocker. If you have severe liver disease or cirrhosis, levels in the blood run 4 to 5 times higher, so a lower starting dose is used.
How you take it matters more than with most pills. Swallow the tablet whole; do not chew, split, or crush it. Take it on an empty stomach, one hour before or two hours after a meal, because a high-fat meal can cause an excessive peak level. Avoid grapefruit juice entirely: the label reports a mean increase in peak level of about 3-fold, ranging up to about 7-fold, with total exposure almost doubled and ranging up to about 5-fold higher. Common side effects include swelling in the ankles or feet, headache, dizziness, flushing, palpitations, stuffy nose, tiredness, and sore throat. The label states it should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus, so tell your prescriber if you are pregnant or planning to become pregnant. This page is general information, not medical advice; talk with your doctor or pharmacist about your own situation, and get medical help right away if you develop chest pain.
This Nisoldipine Er information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Nisoldipine Er on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
Browse more medications: starting with N · full A-Z directory · by condition · common drugs
Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.