Impact-Site-Verification: 2721d812-1059-4270-b9fa-5c1654788cd1

Nisoldipine Er Tablet — prescription drug image

Nisoldipine Er

Nisoldipine ER 17MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes

What is Nisoldipine Er?

Nisoldipine ER (extended-release) is a calcium channel blocker used primarily to treat hypertension (high blood pressure) by relaxing the blood vessels, allowing blood to flow more easily. It is typically prescribed for once-daily oral administration to ensure consistent blood levels and effective management of blood pressure throughout the day.

Prescription savings · · · ·

What is Nisoldipine Er ?

Nisoldipine ER (extended-release) is a calcium channel blocker used primarily to treat hypertension (high blood pressure) by relaxing the blood vessels, allowing blood to flow more easily. It is typically prescribed for once-daily oral administration to ensure consistent blood levels and effective management of blood pressure throughout the day.
  • Swelling in your hands, ankles, or feet.
  • Rapid weight gain.
  • Unusual tiredness or weakness.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain.
  • Fast, irregular, or pounding heartbeats.
  • Lightheadedness, dizziness, or fainting.
  • Warmth or redness in your face, neck, arms, or upper chest.
  • Shortness of breath or wheezing.
  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have heart disease, liver disease, stomach problems, or aortic stenosis (narrowing of a valve in your heart).
  • This medicine may make you dizzy or lightheaded. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Rapid weight gain.
  • Shortness of breath or wheezing.
  • Swelling in your hands, ankles, or feet.
  • Unusual tiredness or weakness.
  • Warmth or redness in your face, neck, arms, or upper chest.
What is nisoldipine ER used for?
Nisoldipine extended-release is FDA-approved to treat hypertension (high blood pressure), either alone or with other blood pressure medicines. It is a dihydropyridine calcium channel blocker that relaxes and widens blood vessels, which lowers the resistance blood has to flow against. It is taken once daily. It is not FDA-approved for angina.
Is nisoldipine the same as Sular?
Sular is the brand name for nisoldipine extended-release tablets, and nisoldipine is the active ingredient. Generic nisoldipine extended-release tablets are also available and are what pharmacies commonly dispense for cash-paying patients. Whether a pharmacy can substitute the generic for a brand-name prescription depends on your state's rules and how the prescription was written, so ask your pharmacist.
Why do you have to take nisoldipine ER on an empty stomach?
Food, especially a high-fat meal, changes how much of the drug your body absorbs at once and can cause an excessive peak level in your blood. The label directs that the tablet be taken on an empty stomach, one hour before or two hours after a meal. The tablet also has to be swallowed whole; do not chew, divide, or crush it.
Can you drink grapefruit juice while taking nisoldipine?
No. Grapefruit juice must be avoided with nisoldipine. The label reports a mean increase in peak concentration of about 3-fold, ranging up to about 7-fold, and total exposure almost doubled, ranging up to about 5-fold higher, which can push your blood pressure down too far. Ask your pharmacist if you are unsure about other foods or drinks.
What are the most common side effects of nisoldipine extended-release?
The most commonly reported side effects are swelling in the feet or ankles (peripheral edema), headache, dizziness, flushing, palpitations, nasal congestion, fatigue, and sore throat. Excessive blood pressure lowering can also happen when starting the medicine or adjusting the dose. Contact your prescriber if side effects bother you or do not go away, and seek care right away for chest pain.
Is nisoldipine ER available as a generic?
Yes. Generic nisoldipine extended-release tablets are available, and the generic is what most cash-paying patients are dispensed. Cash prices vary widely from pharmacy to pharmacy, so enter your ZIP above to compare prices near you and use the free Rx.com coupon.
How much does Nisoldipine Er cost without insurance?
The price of Nisoldipine Er without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 35% off retail prices with a free Rx.com coupon.
What are the common side effects of Nisoldipine Er?
Common side effects of Nisoldipine Er may include: Swelling in your hands, ankles, or feet., Rapid weight gain., Unusual tiredness or weakness., Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Chest pain.. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Nisoldipine Er?
Generic versions may be available for Nisoldipine Er. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Nisoldipine Er on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Nisoldipine Er?
The cheapest pharmacy for Nisoldipine Er depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Nisoldipine Er near you.

Nisoldipine Er Coupons & Prices

Nisoldipine ER 17MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Nisoldipine Er Tablet — prescription drug image
Prescription
Nisoldipine Er 17mg (5)
your area ·
QUAD by MEDVi · 4-in-1 ED treatment

4 ED medications in one dose

Sildenafil, tadalafil, PT-141 & L-Citrulline · Works in ~15 min · Lasts up to 36 hours

$114/mo Consult, meds & shipping included 4-in-1 formula
See QUAD by MEDVi Free online visit · No commitment
QUAD by MEDVi is a compounded prescription treatment; eligibility is determined by a licensed provider after an online visit. Pricing and product details are set by MEDVi and may change. Not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer.

Nisoldipine Er prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
8.5mg · Tablet 30 $164.99 $155.17
17mg · Tablet 30 $296.99 $193.21
34mg · Tablet 30 $280.95 $210.25

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

A nisoldipine ER coupon from Rx.com can lower what you pay at the pharmacy counter for generic nisoldipine extended-release tablets, the long-acting calcium channel blocker used to treat high blood pressure. Generic nisoldipine extended-release tablets are available, and they are what most cash-paying patients are dispensed. Cash prices for the same strength and quantity can differ a lot from one pharmacy to the next, even across the street from each other, which is exactly why comparing matters. Rx.com checks prices at more than 60,000 pharmacies nationwide, so enter your ZIP above to see today's price near you and bring the free coupon with you.

What is nisoldipine ER and how does it work?

Nisoldipine extended-release is a dihydropyridine calcium channel blocker. It is FDA-approved to treat hypertension (high blood pressure), either on its own or together with other blood pressure medicines. It works by relaxing and widening your blood vessels, which reduces the resistance your heart has to push against and brings blood pressure down. It is taken once a day as an extended-release tablet.

One important point: nisoldipine is not FDA-approved for angina. Unlike some other medicines in its family, it has no approved use for chest pain. Blood pressure medicines like this one usually do not make you feel different day to day, so keep taking it as prescribed even when you feel fine.

What does nisoldipine ER cost without insurance?

Nisoldipine extended-release is available as a generic, and generics generally do not come with a manufacturer savings card. If you are paying cash, the price you are quoted depends heavily on which pharmacy you walk into. Two pharmacies in the same town can charge very different amounts for the identical strength and count, because each one sets its own cash price. That is why it is worth checking before you fill rather than after.

Rx.com compares prices across more than 60,000 U.S. pharmacies and gives you a free coupon you can show at the counter. There is no membership or signup required, and the coupon is meant for people paying cash rather than using insurance. Enter your ZIP code above to see today's price for your strength and quantity near you, then take the lowest one.

Nisoldipine ER compared with other calcium channel blockers

Nisoldipine ER belongs to the same dihydropyridine family as several other blood pressure medicines your prescriber might consider. These all relax blood vessels, but they differ in how they are dosed, how they are absorbed, and what else they are approved to treat. Related options include:

Nisoldipine extended-release is also sold under the brand name Sular. Generic nisoldipine extended-release tablets are available, and the generic is what pharmacies typically dispense for cash-paying patients. Whether your pharmacy can substitute a generic for a brand-name prescription depends on your state's substitution laws and on how your prescriber wrote the prescription. Never switch between these medicines on your own. They are not interchangeable, and only your prescriber can decide which one fits your blood pressure, your other conditions, and your other prescriptions.

Safety, side effects, and how to take it

Nisoldipine ER has no boxed warning. It should not be used by anyone with a known hypersensitivity to dihydropyridine calcium channel blockers. A few things to know: rarely, people have had more frequent, longer, or more severe angina, or a heart attack, when starting this medicine or increasing the dose, especially with severe obstructive coronary artery disease (about 1.5% with nisoldipine versus 0.9% with placebo). Blood pressure can also drop too far during the first doses or a dose change, particularly if you take other blood pressure medicines, so your prescriber will want to monitor it. Its safety in heart failure has not been established, and caution is advised, especially alongside a beta-blocker. If you have severe liver disease or cirrhosis, levels in the blood run 4 to 5 times higher, so a lower starting dose is used.

How you take it matters more than with most pills. Swallow the tablet whole; do not chew, split, or crush it. Take it on an empty stomach, one hour before or two hours after a meal, because a high-fat meal can cause an excessive peak level. Avoid grapefruit juice entirely: the label reports a mean increase in peak level of about 3-fold, ranging up to about 7-fold, with total exposure almost doubled and ranging up to about 5-fold higher. Common side effects include swelling in the ankles or feet, headache, dizziness, flushing, palpitations, stuffy nose, tiredness, and sore throat. The label states it should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus, so tell your prescriber if you are pregnant or planning to become pregnant. This page is general information, not medical advice; talk with your doctor or pharmacist about your own situation, and get medical help right away if you develop chest pain.

Sources & accuracy

This Nisoldipine Er information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Nisoldipine Er on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

Sponsored
Sesame Care — 350+ medications for $1 without insurance
¿Buscando esta página en español?

Browse more medications: starting with N · full A-Z directory · by condition · common drugs

Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


Don't Miss Out On Savings!

Rx.com does not warrant the accuracy of the information on this website. All information on this site is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of a drug is safe, appropriate, or effective for you. Consult your healthcare professional before using any drug. All logos, brand names and trademarks on this website are the property of their respective owners. Rx.com is not endorsed or affiliated with any brands represented on this website."

Pharmacy discounts are Not Insurance, and are Not Intended as a Substitute for Insurance THE DISCOUNT IS ONLY AVAILABLE AT PARTICIPATING PHARMACIES As an Amazon Associate, we earn from qualifying purchases.

2026 All Rights Reserved | Rx.com®