Ovidrel
Ovidrel 0.5ML of 250MCG/0.5ML
What is Ovidrel?
Ovidrel is used to together with other medications to help treat infertility in women. Ovidrel is the brand name of chorionic gonadotropin (hcg). On average Ovidrel is priced at about $208 for 0.5 mL, recombinant 250 mcg/0.5 ml subcutaneous solution. Luckily, you can use our Rx.com savings offer to receive an Ovidrel discount of up to 80% off the retail price at participating pharmacies near you.Side Effects
- Unexplained weight gain, bloating
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Severe abdominal pain, nausea, vomiting, diarrhea
Warnings
- Tell your doctor if you are breastfeeding, you have thyroid or adrenal gland problems, or you have abnormal vaginal bleeding that has not been checked by a doctor.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- This medicine may cause more than one egg at a time to be released from your ovary. If this happens, you may become pregnant with more than one baby. Talk with your doctor about this risk before you start using this medicine.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Unexplained weight gain, bloating
Prescription savings · · · ·
What is Ovidrel ?
Ovidrel is used to together with other medications to help treat infertility in women. Ovidrel is the brand name of chorionic gonadotropin (hcg). On average Ovidrel is priced at about $208 for 0.5 mL, recombinant 250 mcg/0.5 ml subcutaneous solution. Luckily, you can use our Rx.com savings offer to receive an Ovidrel discount of up to 80% off the retail price at participating pharmacies near you.- Unexplained weight gain, bloating
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Severe abdominal pain, nausea, vomiting, diarrhea
- Vision problems
- Trouble breathing
- Sudden, severe headache, chest pain, or leg pain
- Urinating less than usual
- Tell your doctor if you are breastfeeding, you have thyroid or adrenal gland problems, or you have abnormal vaginal bleeding that has not been checked by a doctor.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- This medicine may cause more than one egg at a time to be released from your ovary. If this happens, you may become pregnant with more than one baby. Talk with your doctor about this risk before you start using this medicine.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Unexplained weight gain, bloating
- Urinating less than usual
- Vision problems
Ovidrel Coupons & Prices
Ovidrel 0.5ML of 250MCG/0.5ML
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Looking for an Ovidrel coupon? Ovidrel (choriogonadotropin alfa) is a brand-name recombinant hCG "trigger shot" used in fertility treatment, and because there is no generic version, the price can be a real concern for people paying out of pocket. Rx.com offers a free cash-price coupon you can use at the pharmacy counter, even if you are uninsured, on Medicare, or your insurance will not cover fertility medication. Enter your ZIP above to see today's Ovidrel price near you.
What is Ovidrel and how does it work?
Ovidrel is a recombinant form of human chorionic gonadotropin (hCG), a hormone that acts like the body's natural mid-cycle LH surge. In fertility treatment it is given as a single 250 mcg subcutaneous "trigger shot" to induce final follicular maturation and early luteinization after the ovaries have been stimulated with an FSH medication. It is FDA-approved for assisted reproductive technology (ART), where it triggers ovulation before egg retrieval in an IVF cycle, and to induce ovulation and pregnancy in anovulatory infertile women whose infertility is not due to primary ovarian failure.
Because Ovidrel is a potent hormone, treatment is directed by a fertility specialist who monitors your response with ultrasound and bloodwork and times the injection precisely. It is not a general fertility supplement or an over-the-counter product.
Ovidrel cost: manufacturer savings card vs. Rx.com cash coupon
Ovidrel is brand-only with no FDA-approved generic, so it is often one of the pricier items in a fertility cycle. There are two main ways to lower what you pay. EMD Serono, the maker of Ovidrel, runs an official savings program (Fertility LifeLines / the manufacturer's fertility savings site) for eligible patients. Manufacturer savings cards like this are generally limited to people with commercial (private) insurance and typically exclude those with Medicare, Medicaid, or no insurance, and the exact terms and eligibility can change, so confirm the current details with the program directly.
The Rx.com cash coupon works differently. It is a discount on the cash price rather than an insurance benefit, so you can use it when you are uninsured, when you have Medicare, or when a manufacturer card is declined or does not apply. You do not run it through insurance. Enter your ZIP above to compare today's Ovidrel price at pharmacies near you, then bring the coupon to the counter. If your fertility clinic uses a specialty pharmacy, ask whether the coupon can be applied there as well.
Ovidrel alternatives and related fertility medications
Ovidrel is one part of a stimulated fertility cycle, and your specialist chooses medications based on your treatment plan. Related injectable gonadotropins used to stimulate the ovaries include Gonal-f and Follistim (both recombinant FSH) and Menopur (menotropins). Cetrotide is used to prevent premature ovulation during stimulation.
Other hCG products are sometimes used as trigger shots, including Novarel and Pregnyl, which are urinary-derived hCG rather than the recombinant hCG in Ovidrel; they are related but not identical products. Clomid (clomiphene) is an oral option used in some ovulation-induction plans. Only your fertility provider can decide which medication and dose are right for you, so do not switch products on your own.
Ovidrel safety and side effects
Ovidrel is a potent gonadotropin and must be used under the supervision of a fertility specialist. The most serious concern is Ovarian Hyperstimulation Syndrome (OHSS) and ovarian enlargement, which can develop rapidly and become serious. Get medical help right away for severe pelvic or abdominal pain, nausea, vomiting, rapid weight gain, decreased urination, or shortness of breath. Other risks include ovarian torsion, ovarian cysts, an increased chance of multiple births (twins or more), and, rarely, blood clots (arterial or venous thromboembolism, including stroke). Allergic or hypersensitivity reactions are also possible. The most common local effects are injection-site pain and bruising.
Ovidrel should not be used if you have had a prior hypersensitivity to hCG, primary ovarian failure, uncontrolled thyroid or adrenal dysfunction, an uncontrolled organic intracranial lesion such as a pituitary tumor, abnormal uterine bleeding of undetermined origin, an ovarian cyst or enlargement of undetermined origin, or a sex-hormone-dependent tumor of the reproductive tract. This is general information, not medical advice. Talk with your fertility provider about your full history and any medications you take.
This Ovidrel information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Ovidrel on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.