Phenazopyridine Hcl
Phenazopyridine HCl 200MG
What is Phenazopyridine Hcl?
Pyridium is an analgesic used to relieve symptoms associated with a urinary tract infection. Phenazopyridine is the generic version of Pyridium. On average Pyridium is priced at $40 for a supply of 6, 200 mg tablets. You can use our Rx.com savings offer to get a Pyridium discount of up to 80% off of the retail price at participating pharmacies near you.Side Effects
- Yellowing of the skin or eyes
- Skin rash or hives, trouble breathing
- Headache
Warnings
- This medicine may stain soft contact lenses. You may not want to wear your contacts while taking this medicine.
- This medicine can turn urine a red or orange color. This is normal.
- Check with your doctor before taking phenazopyridine if you have kidney or liver problems or are pregnant or breastfeeding.
Prescription savings · · · ·
What is Phenazopyridine Hcl ?
Pyridium is an analgesic used to relieve symptoms associated with a urinary tract infection. Phenazopyridine is the generic version of Pyridium. On average Pyridium is priced at $40 for a supply of 6, 200 mg tablets. You can use our Rx.com savings offer to get a Pyridium discount of up to 80% off of the retail price at participating pharmacies near you.- Yellowing of the skin or eyes
- Skin rash or hives, trouble breathing
- Headache
- This medicine may stain soft contact lenses. You may not want to wear your contacts while taking this medicine.
- This medicine can turn urine a red or orange color. This is normal.
- Check with your doctor before taking phenazopyridine if you have kidney or liver problems or are pregnant or breastfeeding.
Phenazopyridine Hcl Coupons & Prices
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Use the free Rx.com phenazopyridine HCl coupon to compare cash prices at more than 60,000 pharmacies before you fill your prescription. Phenazopyridine hydrochloride is a urinary analgesic that eases the pain, burning, and urgency caused by irritation of the lower urinary tract, and it is available as an FDA-approved generic in 100 mg and 200 mg prescription tablets. Cash prices for the same tablets can differ quite a bit from one pharmacy to the next, even between stores on the same street, so it pays to check. Enter your ZIP code above to see today's price near you and bring the coupon to the pharmacy counter.
What is phenazopyridine HCl and how does it work?
Phenazopyridine hydrochloride is a urinary analgesic, an azo dye that is excreted in the urine and has a local analgesic effect on the lining of the urinary tract (the exact mechanism is not known). It is not an antibiotic and it does not kill bacteria. It eases the pain, burning, urgency, and frequent urge to urinate while another treatment handles the cause.
The FDA-approved label covers symptomatic relief of pain, burning, urgency, frequency, and other discomfort from irritation of the lower urinary tract mucosa caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters. Prescription tablets come in 100 mg and 200 mg strengths. The label's average adult dose is two 100 mg tablets three times a day after meals, or one 200 mg tablet three times a day after meals. Because it treats symptoms only, it is used alongside an antibiotic for a urinary tract infection, never instead of one. The label limits use to 2 days when it is given with antibacterial therapy for a UTI. Swallow tablets whole with a full glass of water; chewing or crushing them can stain your teeth.
What does phenazopyridine cost without insurance?
Phenazopyridine HCl is available as a generic, and generics are filled by many manufacturers, so no single pharmacy sets the price. That is exactly why cash prices vary widely from pharmacy to pharmacy for the same strength and quantity. Without insurance you pay the pharmacy's cash price unless you bring a discount coupon, and even people with insurance sometimes find the coupon price beats their copay. It is always worth comparing both.
Rx.com compares cash prices across more than 60,000 pharmacies, including the big chains and independents near you. Enter your ZIP code above to see today's price for your strength and quantity, then show the coupon at the counter. Also worth knowing: phenazopyridine is sold over the counter in strengths of 95, 97.5, or 99.5 mg as AZO Urinary Pain Relief, AZO-Standard, Uristat, and similar brands, so it is reasonable to price-check the OTC option too and ask your pharmacist which fits your situation.
Phenazopyridine vs. UTI antibiotics: what is the difference?
This is the single most important distinction on this page. Phenazopyridine relieves symptoms. Antibiotics treat the infection. If you have a urinary tract infection, your provider will typically prescribe an antibiotic, and phenazopyridine may be added for the first day or two while the antibiotic starts working. Taking phenazopyridine alone can mask symptoms and delay proper diagnosis and treatment.
Common antibiotics prescribed for urinary tract infections include nitrofurantoin and its brand Macrobid, sulfamethoxazole and trimethoprim and its brand Bactrim, cephalexin, ciprofloxacin, and fosfomycin. Methenamine hippurate is used differently again. Which one is right, and whether phenazopyridine belongs alongside it, is a decision for your provider and depends on your infection and your health history. You can compare prices on any of these with an Rx.com coupon.
Safety, side effects, and what to expect
Phenazopyridine has no boxed warning. It is contraindicated in people with hypersensitivity to phenazopyridine and in people with renal insufficiency. It turns urine a reddish-orange color, which the label describes as harmless, but the label also warns that it may stain fabric, and staining of contact lenses has been reported. It can interfere with urinalysis, including urine glucose and ketone dipstick tests, so tell any provider or lab that you are taking it. A yellowish tinge in your skin or the whites of your eyes may mean the drug is building up because your kidneys are not clearing it, and should prompt you to stop the drug and contact your provider.
Other reported effects include headache, rash, itching, and stomach upset. Uncommon but serious risks include methemoglobinemia, hemolytic anemia (higher risk if you have G6PD deficiency), kidney or liver toxicity, and rare anaphylactoid-like reactions; these are typically tied to overdose or prolonged use. Long-term administration has caused tumors in animal studies, and use in pregnancy is advised only if clearly needed. Do not exceed 2 days of use with an antibiotic, and do not let symptom relief delay diagnosis and treatment of the underlying cause. This information is not medical advice. Talk with your doctor or pharmacist about your own situation.
This Phenazopyridine Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Phenazopyridine Hcl on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.