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Phenazopyridine Hcl

Phenazopyridine HCl 200MG

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What is Phenazopyridine Hcl?

Pyridium is an analgesic used to relieve symptoms associated with a urinary tract infection. Phenazopyridine is the generic version of Pyridium. On average Pyridium is priced at $40 for a supply of 6, 200 mg tablets. You can use our Rx.com savings offer to get a Pyridium discount of up to 80% off of the retail price at participating pharmacies near you.

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What is Phenazopyridine Hcl ?

Pyridium is an analgesic used to relieve symptoms associated with a urinary tract infection. Phenazopyridine is the generic version of Pyridium. On average Pyridium is priced at $40 for a supply of 6, 200 mg tablets. You can use our Rx.com savings offer to get a Pyridium discount of up to 80% off of the retail price at participating pharmacies near you.
  • Yellowing of the skin or eyes
  • Skin rash or hives, trouble breathing
  • Headache
  • This medicine may stain soft contact lenses. You may not want to wear your contacts while taking this medicine.
  • This medicine can turn urine a red or orange color. This is normal.
  • Check with your doctor before taking phenazopyridine if you have kidney or liver problems or are pregnant or breastfeeding.
How long does it take for phenazopyridine to work for UTI pain?
Phenazopyridine acts directly on the lining of the lower urinary tract, and many people notice relief of burning and urgency within the first few doses. It is typically taken three times daily after meals. If your pain is not improving, or is getting worse, contact your provider rather than continuing on your own, because the underlying cause still needs treatment.
Does phenazopyridine cure a UTI or just relieve the symptoms?
It relieves symptoms only. Phenazopyridine is a urinary analgesic, not an antibiotic, and it has no effect on the bacteria causing an infection. That is why it is used alongside an antibiotic and not instead of one. Taking it by itself can hide symptoms and delay the diagnosis and treatment you actually need.
Why does phenazopyridine turn your urine orange, and will it stain?
Phenazopyridine is an azo dye, so it colors urine a reddish-orange as it passes through the urinary tract. The color itself is harmless and expected. The label warns that it may stain fabric, and staining of contact lenses has been reported, so take care with clothing and ask your eye doctor or pharmacist about wearing glasses instead of lenses while you are on it. It can also interfere with urinalysis, including urine glucose and ketone dipsticks, so tell your provider or lab you are taking it.
How many days can you take phenazopyridine safely?
The label says not to exceed 2 days of use when phenazopyridine is taken together with antibacterial therapy for a urinary tract infection. Longer use raises the risk of the drug accumulating, and serious effects such as methemoglobinemia, hemolytic anemia, and kidney or liver toxicity are generally linked to overdose or prolonged use. Follow the exact directions your provider gives you.
Is prescription phenazopyridine stronger than over-the-counter AZO?
Not really. It is the same active ingredient, and the per-dose and per-day amounts are essentially the same. The FDA prescription label doses the 100 mg tablet as two tablets three times daily, which is 200 mg per dose, while maximum-strength OTC products such as AZO Urinary Pain Relief contain 99.5 mg and are also taken as two tablets three times daily, which is 199 mg per dose. The real difference is packaging: the prescription 200 mg tablet delivers that same standard dose in a single pill. Ask your pharmacist which product suits your situation, and remember that neither version treats an infection.
How much does Phenazopyridine Hcl cost without insurance?
The price of Phenazopyridine Hcl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Phenazopyridine Hcl?
Common side effects of Phenazopyridine Hcl may include: Yellowing of the skin or eyes, Skin rash or hives, trouble breathing, Headache. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Phenazopyridine Hcl?
Generic versions may be available for Phenazopyridine Hcl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Phenazopyridine Hcl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Phenazopyridine Hcl?
The cheapest pharmacy for Phenazopyridine Hcl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Phenazopyridine Hcl near you.

Phenazopyridine Hcl Coupons & Prices

Phenazopyridine HCl 200MG

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Phenazopyridine Hcl Tablet — prescription drug image
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Use the free Rx.com phenazopyridine HCl coupon to compare cash prices at more than 60,000 pharmacies before you fill your prescription. Phenazopyridine hydrochloride is a urinary analgesic that eases the pain, burning, and urgency caused by irritation of the lower urinary tract, and it is available as an FDA-approved generic in 100 mg and 200 mg prescription tablets. Cash prices for the same tablets can differ quite a bit from one pharmacy to the next, even between stores on the same street, so it pays to check. Enter your ZIP code above to see today's price near you and bring the coupon to the pharmacy counter.

What is phenazopyridine HCl and how does it work?

Phenazopyridine hydrochloride is a urinary analgesic, an azo dye that is excreted in the urine and has a local analgesic effect on the lining of the urinary tract (the exact mechanism is not known). It is not an antibiotic and it does not kill bacteria. It eases the pain, burning, urgency, and frequent urge to urinate while another treatment handles the cause.

The FDA-approved label covers symptomatic relief of pain, burning, urgency, frequency, and other discomfort from irritation of the lower urinary tract mucosa caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters. Prescription tablets come in 100 mg and 200 mg strengths. The label's average adult dose is two 100 mg tablets three times a day after meals, or one 200 mg tablet three times a day after meals. Because it treats symptoms only, it is used alongside an antibiotic for a urinary tract infection, never instead of one. The label limits use to 2 days when it is given with antibacterial therapy for a UTI. Swallow tablets whole with a full glass of water; chewing or crushing them can stain your teeth.

What does phenazopyridine cost without insurance?

Phenazopyridine HCl is available as a generic, and generics are filled by many manufacturers, so no single pharmacy sets the price. That is exactly why cash prices vary widely from pharmacy to pharmacy for the same strength and quantity. Without insurance you pay the pharmacy's cash price unless you bring a discount coupon, and even people with insurance sometimes find the coupon price beats their copay. It is always worth comparing both.

Rx.com compares cash prices across more than 60,000 pharmacies, including the big chains and independents near you. Enter your ZIP code above to see today's price for your strength and quantity, then show the coupon at the counter. Also worth knowing: phenazopyridine is sold over the counter in strengths of 95, 97.5, or 99.5 mg as AZO Urinary Pain Relief, AZO-Standard, Uristat, and similar brands, so it is reasonable to price-check the OTC option too and ask your pharmacist which fits your situation.

Phenazopyridine vs. UTI antibiotics: what is the difference?

This is the single most important distinction on this page. Phenazopyridine relieves symptoms. Antibiotics treat the infection. If you have a urinary tract infection, your provider will typically prescribe an antibiotic, and phenazopyridine may be added for the first day or two while the antibiotic starts working. Taking phenazopyridine alone can mask symptoms and delay proper diagnosis and treatment.

Common antibiotics prescribed for urinary tract infections include nitrofurantoin and its brand Macrobid, sulfamethoxazole and trimethoprim and its brand Bactrim, cephalexin, ciprofloxacin, and fosfomycin. Methenamine hippurate is used differently again. Which one is right, and whether phenazopyridine belongs alongside it, is a decision for your provider and depends on your infection and your health history. You can compare prices on any of these with an Rx.com coupon.

Safety, side effects, and what to expect

Phenazopyridine has no boxed warning. It is contraindicated in people with hypersensitivity to phenazopyridine and in people with renal insufficiency. It turns urine a reddish-orange color, which the label describes as harmless, but the label also warns that it may stain fabric, and staining of contact lenses has been reported. It can interfere with urinalysis, including urine glucose and ketone dipstick tests, so tell any provider or lab that you are taking it. A yellowish tinge in your skin or the whites of your eyes may mean the drug is building up because your kidneys are not clearing it, and should prompt you to stop the drug and contact your provider.

Other reported effects include headache, rash, itching, and stomach upset. Uncommon but serious risks include methemoglobinemia, hemolytic anemia (higher risk if you have G6PD deficiency), kidney or liver toxicity, and rare anaphylactoid-like reactions; these are typically tied to overdose or prolonged use. Long-term administration has caused tumors in animal studies, and use in pregnancy is advised only if clearly needed. Do not exceed 2 days of use with an antibiotic, and do not let symptom relief delay diagnosis and treatment of the underlying cause. This information is not medical advice. Talk with your doctor or pharmacist about your own situation.

Sources & accuracy

This Phenazopyridine Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Phenazopyridine Hcl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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