Promethazine-Dm Coupons & Prices

Searching for a promethazine DM coupon? Promethazine DM (promethazine hydrochloride / dextromethorphan hydrobromide) is a prescription cough-and-cold syrup that combines a sedating antihistamine with a cough suppressant, and there's no current branded version of the combination — every prescription is filled generically. That doesn't mean every pharmacy charges the same price for it, though: cash prices for this syrup can vary widely from one pharmacy to the next. Rx.com compares pricing across 60,000+ pharmacies so you can see where it costs less near you — enter your ZIP above to check today's price.

What Is Promethazine DM and How Does It Work?

Promethazine DM combines two active ingredients in one oral syrup: promethazine hydrochloride, a phenothiazine antihistamine, and dextromethorphan hydrobromide, a cough suppressant that works on NMDA receptors. It's FDA-approved for the temporary relief of cough and upper respiratory symptoms — including runny nose and sneezing — associated with allergies or the common cold.

It's available only by prescription and is not approved for children under 2 years old.

How Much Does Promethazine DM Cost, and How Can You Save?

Because promethazine DM is sold only as a generic, there's no brand-name price to compare it against — but that doesn't mean every pharmacy's cash price is the same. Prices for generic syrups like this one can differ significantly from pharmacy to pharmacy in the same city, so comparing before you fill is one of the most reliable ways to control what you pay.

There's no manufacturer savings card for this generic combination. The best way to find out what it actually costs where you live is to enter your ZIP code above and compare current prices across pharmacies near you.

Promethazine DM vs. Related Cough, Allergy, and Congestion Medications

Promethazine DM bundles two ingredients you can also get separately: promethazine alone (an antihistamine formerly sold under the brand name Phenergan, which is no longer marketed as a branded product and is now available only generically) and dextromethorphan alone (an OTC cough suppressant). Combining them in one syrup means one prescription instead of two products.

A related but different product is promethazine with codeine (promethazine AC). It swaps the cough suppressant dextromethorphan for the opioid codeine — which makes it a federally controlled substance, unlike promethazine DM, which is not scheduled. If your cough is productive (bringing up mucus) rather than dry, your doctor might instead consider guaifenesin, an expectorant used for cold-related chest congestion that works by thinning mucus rather than suppressing cough or treating allergy symptoms.

Safety Information for Promethazine DM

Promethazine DM carries an FDA boxed warning: it must never be given to children under 2 years old because of the risk of fatal respiratory depression. In children 2 and older, it should be used with caution, and it should never be combined with other drugs that depress breathing.

• Contraindicated with MAO inhibitors (risk of hyperpyrexia, hypotension, and death), in comatose patients, and in people with lower-respiratory-tract disease such as asthma
• Causes significant CNS depression and sedation and can impair driving or operating machinery
• May lower the seizure threshold and carries a risk of neuroleptic malignant syndrome
• Contains roughly 7% alcohol
• Has additive CNS-depressant effects with alcohol, sedatives, opioids, and other depressant medications

This is general safety information, not medical advice — talk to your doctor or pharmacist about whether promethazine DM is right for you or your child, and about any other medications you're taking.