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Tarpeyo Capsule Delayed Release — prescription drug image

Tarpeyo

Tarpeyo 4MG

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What is Tarpeyo?

Tarpeyo is a medication that helps reduce protein in the urine for patients with primary immunoglobulin A nephropathy, a kidney disease. It works by decreasing inflammation in the body.

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What is Tarpeyo ?

Tarpeyo is a medication that helps reduce protein in the urine for patients with primary immunoglobulin A nephropathy, a kidney disease. It works by decreasing inflammation in the body.

Source: MedlinePlus, U.S. National Library of Medicine

  • Slow growth in children
  • Round, puffy face
  • Lightheadedness, dizziness, or fainting
  • Diarrhea, loss of appetite
  • Fever, chills, cough, sore throat, body aches
  • Dark freckles, skin color changes, coldness, weakness, tiredness, nausea, vomiting, weight loss
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Thicker or more hair on your body and face
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease (including cirrhosis), diabetes, high blood pressure, osteoporosis, stomach ulcers, any type of infection (including tuberculosis), allergies, or a family history of cataracts, diabetes, or glaucoma.
  • This medicine may cause the following problems:Adrenal problemsIncreased risk of infectionErosive esophagitis (damage to the lining of the esophagus)Slow growth in childrenIncreased risk for cancer (including Kaposi€™s sarcoma)
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is Tarpeyo used to treat?
Tarpeyo is FDA-approved to reduce the loss of kidney function in adults with primary IgA nephropathy (IgAN) who are at risk of disease progression. It is a targeted, delayed-release form of budesonide that acts on immune tissue in the gut. It is approved only for IgA nephropathy and is not a substitute for other budesonide products used in conditions like Crohn's disease, ulcerative colitis, or asthma.
Is Tarpeyo a steroid?
Yes. Tarpeyo contains budesonide, which is a corticosteroid (a glucocorticoid). It is formulated to release mainly in the lower small intestine to target gut immune tissue, but it still carries the usual corticosteroid precautions, such as adrenal suppression with long-term use, increased infection risk, and effects on blood sugar, blood pressure, and bone health.
How much does Tarpeyo cost without insurance?
The cash price varies by pharmacy and location and changes over time, so we don't list a fixed dollar amount. Enter your ZIP above to see today's Rx.com discount price at pharmacies near you. Because Tarpeyo is brand-only with no generic, it can be expensive, so it's worth comparing the Rx.com cash coupon against the manufacturer savings program at tarpeyo.com/savings-and-support to see which is lower for you.
Is there a generic version of Tarpeyo?
No. There is currently no generic version of Tarpeyo available; it is a brand-name product. The active ingredient is budesonide, but other budesonide products are not approved for IgA nephropathy and are not interchangeable with Tarpeyo. To lower your cost, compare the Rx.com cash coupon with the manufacturer savings card.
How long do you take Tarpeyo for IgA nephropathy?
The recommended course is 16 mg taken once daily for 9 months. Take the capsules in the morning, at least 1 hour before a meal, and swallow them whole without opening, crushing, or chewing. Do not stop Tarpeyo suddenly; your provider will taper the dose at the end of treatment to let your body's hormone system recover.
How much does Tarpeyo cost without insurance?
The price of Tarpeyo without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 59% off retail prices with a free Rx.com coupon.
What are the common side effects of Tarpeyo?
Common side effects of Tarpeyo may include: Slow growth in children, Round, puffy face, Lightheadedness, dizziness, or fainting, Diarrhea, loss of appetite, Fever, chills, cough, sore throat, body aches. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Tarpeyo?
Generic versions may be available for Tarpeyo. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Tarpeyo on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Tarpeyo?
The cheapest pharmacy for Tarpeyo depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Tarpeyo near you.

Tarpeyo Coupons & Prices

Tarpeyo 4MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Tarpeyo Capsule Delayed Release — prescription drug image
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Looking for a Tarpeyo coupon? Tarpeyo (budesonide delayed-release capsules) is a brand-name corticosteroid FDA-approved to slow the loss of kidney function in adults with primary IgA nephropathy (IgAN) who are at risk of disease progression. Because it is brand-only with no generic yet, the cash price can be high. Enter your ZIP above to see today's Rx.com discount price at pharmacies near you, and compare it against the manufacturer savings card below to find your lowest out-of-pocket cost.

What Tarpeyo is and how it works

Tarpeyo is a targeted, delayed-release oral form of the corticosteroid budesonide. It is FDA-approved to reduce the loss of kidney function in adults with primary immunoglobulin A nephropathy (IgAN, also called IgA nephropathy) who are at risk of disease progression. The capsules are designed to release in the distal ileum (the lower part of the small intestine), where they act on gut-associated immune tissue to reduce production of the galactose-deficient IgA1 antibodies thought to drive IgAN.

An important note: budesonide is used in other formulations for conditions like Crohn's disease, ulcerative colitis, and asthma, but Tarpeyo specifically is approved only for IgA nephropathy. It is not interchangeable with other budesonide products and should not be substituted for them. This information is educational and not medical advice; your kidney specialist decides whether Tarpeyo is right for you.

Tarpeyo cost and savings: manufacturer card vs. Rx.com cash coupon

Tarpeyo is a brand-name drug with no generic available, so it is one of the pricier prescriptions and the way you pay matters. There are two main ways to lower your cost, and they work in different situations:

  • Manufacturer savings card. The maker of Tarpeyo offers a savings-and-support program. These commercial copay cards are generally limited to patients with private/commercial insurance and typically exclude government plans like Medicare and Medicaid. Terms, eligibility, and any savings limits vary and can change, so check the official page for current details: Tarpeyo Savings and Support. That program may also include patient-assistance options for eligible patients who cannot afford their medication.
  • Rx.com cash coupon. Our free discount coupon is a cash-pay option, so it can help when the manufacturer card doesn't apply, for example if you are uninsured, on Medicare or Medicaid, or if the card is declined at the pharmacy. Enter your ZIP above to see today's price at pharmacies near you.

You cannot combine a manufacturer copay card with a cash discount coupon on the same fill, but you can compare both and use whichever is lower for you.

Alternatives and related medications

Tarpeyo is one of several treatments used in IgA nephropathy and related conditions. Your nephrologist may consider other options depending on your case:

  • Filspari and Fabhalta are other medications used in IgA nephropathy.
  • Budesonide is the active ingredient in Tarpeyo, and other budesonide brands such as Entocort EC and Uceris are used for gut conditions like Crohn's disease and ulcerative colitis, not IgA nephropathy.

These drugs are not interchangeable, and only your provider can decide which is appropriate. Whichever you are prescribed, you can enter your ZIP above to check the Rx.com cash price for it.

Safety and important precautions

Tarpeyo is not a boxed-warning drug, but as a corticosteroid it carries meaningful risks, especially with the recommended 9-month course. Long-term use can cause hypercorticism and suppress the body's own adrenal (HPA) hormone system, with higher risk in people with moderate-to-severe liver impairment. It can also increase the risk of infection and weaken the immune response. Because of this, it is generally avoided in people with active or quiet tuberculosis, untreated fungal, bacterial, viral, or parasitic infections, or eye herpes; non-immune patients should avoid exposure to chickenpox and measles, and live/attenuated vaccines should be avoided during treatment.

Tarpeyo may also worsen high blood pressure, diabetes or high blood sugar, osteoporosis, peptic ulcers, glaucoma, and cataracts. Do not stop it abruptly; your provider will taper the dose to let your hormone system recover. Avoid potent CYP3A4 inhibitors (such as ketoconazole or ritonavir) and grapefruit juice, which raise budesonide levels. Swallow the capsules whole (do not open, crush, or chew), and take them in the morning at least 1 hour before a meal. This is a summary, not medical advice; talk with your provider or pharmacist about your full history and medications.

Sources & accuracy

This Tarpeyo information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Tarpeyo on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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