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Tri-Legest Fe Disp Pack — prescription drug image

Tri-Legest Fe

Tri-Legest Fe 28 Tablets

Prescriptions & Refills
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What is Tri-Legest Fe?

Tri-Legest Fe is a combination drug used as a contraceptive to prevent pregnancy in women. The generic version of Tri-Legest Fe is ethinyl estradiol/norethindrone. You can use our Rx.com Tri-Legest Fe savings card to get an average Tri-Legest Fe discount of about up to 80% off of the retail price when purchased at a participating pharmacy near you.

Prescription savings · · · ·

What is Tri-Legest Fe ?

Tri-Legest Fe is a combination drug used as a contraceptive to prevent pregnancy in women. The generic version of Tri-Legest Fe is ethinyl estradiol/norethindrone. You can use our Rx.com Tri-Legest Fe savings card to get an average Tri-Legest Fe discount of about up to 80% off of the retail price when purchased at a participating pharmacy near you.
  • Nausea and vomiting
  • Headache
  • Breast tenderness
  • Weight changes
  • Mood changes
  • Abdominal cramps and bloating
  • Spotting or breakthrough bleeding
  • Changes in menstrual flow
  • Increased risk of blood clots, heart attack, and stroke
  • Not recommended for smokers over the age of 35
  • Possible increased risk of breast and cervical cancers
  • May cause or worsenate problems with liver, gallbladder, or adrenal function
  • Not to be used during pregnancy
  • Might cause issues with lens wearers, such as discomfort
  • Immediate discontinuation advised if jaundice develops
  • Should not be used as protection against HIV infection or other sexually transmitted diseases
What is Tri-Legest Fe used for?
Tri-Legest Fe is FDA-approved for two things: preventing pregnancy in women who choose to use a combined oral contraceptive, and treating moderate acne vulgaris in females 15 years and older who have started menstruating, want oral contraception, have no contraindications to combined oral contraceptives, and have not responded to topical acne medicines. Clinicians also prescribe combined pills like this one off-label for cycle regulation and other menstrual concerns; that decision belongs with your prescriber.
Is Tri-Legest Fe the same as Estrostep Fe?
Estrostep Fe is the reference brand and Tri-Legest Fe is Teva's branded generic of that same triphasic norethindrone acetate and ethinyl estradiol regimen, with ferrous fumarate 75 mg tablets for the last seven days. Tilia Fe is another therapeutically similar branded generic. Ask your pharmacist which product they stock, since availability and cash price vary by store.
Does Tri-Legest Fe help with acne?
Yes, treatment of moderate acne vulgaris is one of its two FDA-approved uses, but the label scopes it narrowly: females 15 years and older who have started menstruating, who want oral contraception anyway, who have no contraindications to combined oral contraceptive therapy, and whose acne has not responded to topical anti-acne medications. It is not intended as an acne treatment for someone who does not want contraception.
What happens if I miss a dose of Tri-Legest Fe?
Missing doses can reduce how well the pill prevents pregnancy, and the missed-pill instructions depend on which tablets you missed and how many. Follow the missed-dose directions in the patient labeling that comes with your pack, and call your pharmacist or prescriber if you are not sure what to do. You may need backup contraception. Note that certain medicines, including rifampin, some anticonvulsants, and St. John's wort, can also make it less effective.
What are the side effects of Tri-Legest Fe?
The most serious risks on the label are blood clots and other arterial and venous events such as heart attack, stroke, deep vein thrombosis and pulmonary embolism, along with raised blood pressure, liver tumors, gallbladder disease, a possible small increase in breast cancer risk, and high triglycerides with pancreatitis. The boxed warning is about smoking: cigarette smoking raises the risk of serious cardiovascular events, and combined oral contraceptives are contraindicated in women over 35 who smoke. Ask your doctor or pharmacist about the full list of possible side effects and what to watch for.
How much does Tri-Legest Fe cost without insurance?
The price of Tri-Legest Fe without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Tri-Legest Fe?
Common side effects of Tri-Legest Fe may include: Nausea and vomiting, Headache, Breast tenderness, Weight changes, Mood changes. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Tri-Legest Fe?
Generic versions may be available for Tri-Legest Fe. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Tri-Legest Fe on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Tri-Legest Fe?
The cheapest pharmacy for Tri-Legest Fe depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Tri-Legest Fe near you.

Tri-Legest Fe Coupons & Prices

Tri-Legest Fe 28 Tablets

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Tri-Legest Fe Disp Pack — prescription drug image
Prescription
Tri-Legest Fe 1 package (28 tablets), 1-20/1-30/1-35mg-mcg (1)
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Looking for a Tri-Legest Fe coupon? Tri-Legest Fe is Teva's branded generic of Estrostep Fe, a triphasic combined birth control pill that contains norethindrone acetate and ethinyl estradiol, plus seven brown ferrous fumarate (iron) tablets that complete the 28-day pack. There is no manufacturer savings card for it, and the cash price for the same 28-day pack can differ a great deal from one pharmacy to the next, even between stores a few blocks apart. Rx.com compares prices at more than 60,000 pharmacies so you can see what today's price looks like near you before you fill. Enter your ZIP above to see today's price.

What is Tri-Legest Fe and how does it work?

Tri-Legest Fe is a combined oral contraceptive. It pairs a progestin (norethindrone acetate) with an estrogen (ethinyl estradiol). It is called triphasic because the estrogen dose steps up across the cycle rather than staying flat. Each 28-day pack contains 5 light pink tablets (1 mg norethindrone acetate / 20 mcg ethinyl estradiol), 7 light yellow tablets (1 mg / 30 mcg), 9 light blue tablets (1 mg / 35 mcg), and then 7 brown tablets that are ferrous fumarate 75 mg. The brown tablets are the non-hormonal placebo week. The iron in them serves no therapeutic purpose and is not a treatment for anemia; it is simply there to make the 28-day habit easier to keep.

The FDA-approved uses of this tablet are (1) prevention of pregnancy in women who elect to use a combined oral contraceptive, and (2) treatment of moderate acne vulgaris in females 15 years and older who have started menstruating, want oral contraception, have no contraindications to combined oral contraceptive therapy, and have not responded to topical acne medicines. Like other combined pills, clinicians also prescribe it off-label for things such as cycle regulation, heavy or painful periods, PMDD symptoms, endometriosis pain, and PCOS-related concerns. Whether any of that fits you is a conversation for your own prescriber, not a decision to make from a web page.

Tri-Legest Fe cost without insurance and how to compare

There is no manufacturer savings card for Tri-Legest Fe, so if you are paying cash the main lever you have is where you fill it. Pharmacy cash prices for the identical 28-day pack are not standardized: independents, grocery chains, big-box stores, and the large drugstore chains can all land in very different places for the same product on the same day. That is why the comparison step actually matters, and why it is worth re-checking rather than assuming your usual pharmacy is still the best answer.

Some plans cover FDA-approved contraception with no copay, so it is worth checking your insurance first. If you have no coverage, or your plan does not cover this specific product, a discount price may be lower than what you would otherwise pay. Enter your ZIP above to see today's price at pharmacies near you, and compare a few before you transfer your prescription. Rx.com checks more than 60,000 pharmacies, and a coupon price cannot be combined with insurance, so use whichever is genuinely cheaper for you.

Tri-Legest Fe vs. Estrostep Fe and other options

Estrostep Fe is the reference brand; Tri-Legest Fe is Teva's branded generic of that same triphasic norethindrone acetate / ethinyl estradiol formulation with ferrous fumarate tablets. Tilia Fe is another therapeutically similar branded generic of the same regimen. If your prescription is written for one of these, ask your pharmacist which equivalent product they stock, since price and availability often differ by product and by store.

Many other combined pills use the same two hormones but in a single fixed strength for the active weeks rather than a graduated one, including Junel Fe, Microgestin Fe, Larin Fe, and Blisovi Fe. Norethindrone alone is a progestin-only pill and works differently, with different rules for use. These are not interchangeable on your own initiative; switching pills is a prescriber's call. If cost is the reason you are considering a change, bring the compared prices to your appointment.

Safety information to know

Boxed warning: cigarette smoking increases the risk of serious cardiovascular events from combined oral contraceptive use. That risk rises with age, especially over 35, and with the number of cigarettes smoked. Combined oral contraceptives are contraindicated in women over 35 who smoke. Tri-Legest Fe should not be used if you have or have had blood clots (venous thromboembolism) or a thrombogenic disorder, cerebrovascular or coronary artery disease, uncontrolled high blood pressure, migraine with aura (or any migraine if you are over 35), diabetes with vascular complications or lasting more than 20 years, current or past breast cancer or another estrogen- or progestin-sensitive cancer, liver tumors or acute liver disease, undiagnosed abnormal uterine bleeding, or if you are pregnant. It is also contraindicated with hepatitis C treatment containing ombitasvir/paritaprevir/ritonavir because of the risk of liver enzyme elevation.

The label's other warnings include arterial and venous clotting events such as heart attack, stroke, deep vein thrombosis and pulmonary embolism, raised blood pressure, liver tumors, gallbladder disease, a possible small increase in breast cancer risk, high triglycerides with pancreatitis, and higher clot risk around surgery or long periods of immobility. Tri-Legest Fe does not protect against HIV or other sexually transmitted infections. Effectiveness can drop if you miss doses or take enzyme-inducing medicines such as rifampin, certain seizure drugs, or St. John's wort. This is a summary, not medical advice; read the full label and talk with your doctor or pharmacist about your own history.

Sources & accuracy

This Tri-Legest Fe information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Tri-Legest Fe on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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