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Triple Antibiotic

Triple Antibiotic 28GM of 3.5-400-5000

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What is Triple Antibiotic?

Triple Antibiotic is an ointment that combines three antibiotics to help prevent and treat infections in minor cuts, scrapes, and burns. It works by stopping the growth of bacteria, helping your skin heal.

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What is Triple Antibiotic ?

Triple Antibiotic is an ointment that combines three antibiotics to help prevent and treat infections in minor cuts, scrapes, and burns. It works by stopping the growth of bacteria, helping your skin heal.

Source: MedlinePlus, U.S. National Library of Medicine

  • Rash, hives, swelling, or itching that was not there before you started the medicine.
  • For more serious wounds such as puncture wounds, animal bites, or severe burns, you should call your doctor before using this medicine.
  • You should not use this medicine for more than 7 days, unless your doctor has told you to. If your symptoms do not get better or if they get worse, stop using this medicine and call your doctor.
  • If you are pregnant or breastfeeding, talk to your doctor before using this medicine.
Is triple antibiotic ointment the same as Neosporin?
Store-brand and generic triple antibiotic ointment contain the same three active ingredients (bacitracin zinc, neomycin sulfate, and polymyxin B sulfate) at the same strengths as Neosporin Original.
Do I need a prescription for triple antibiotic ointment?
No. It's regulated as an over-the-counter monograph product and can be bought without a prescription.
How often should I apply triple antibiotic ointment?
The label directs applying a small amount, about the size of a fingertip, one to three times daily to the affected area after cleaning it.
Can triple antibiotic ointment cause an allergic reaction?
Yes, it can. Neomycin in particular is a relatively common cause of allergic contact dermatitis with repeated use. Stop use and check with a doctor if a rash or other signs of allergy develop.
Can I use triple antibiotic ointment on a deep wound or animal bite?
No, not without checking with a doctor first. The label specifically advises asking a doctor before use on deep or puncture wounds, animal bites, or serious burns.
How much does Triple Antibiotic cost without insurance?
The price of Triple Antibiotic without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Triple Antibiotic?
Common side effects of Triple Antibiotic may include: Rash, hives, swelling, or itching that was not there before you started the medicine.. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Triple Antibiotic?
Generic versions may be available for Triple Antibiotic. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Triple Antibiotic on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Triple Antibiotic?
The cheapest pharmacy for Triple Antibiotic depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Triple Antibiotic near you.

Triple Antibiotic Coupons & Prices

Triple Antibiotic 28GM of 3.5-400-5000

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Triple Antibiotic Tube — prescription drug image
Prescription
Triple Antibiotic 28.4gm of 3.5-400-5000 (0.5)
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Triple antibiotic ointment combines bacitracin zinc, neomycin sulfate, and polymyxin B sulfate to help prevent infection in minor cuts, scrapes, and burns, and it's sold over the counter without a prescription. It's available under store brands as well as name brands like Neosporin, and shelf prices for the identical combination can differ between pharmacies — enter your ZIP above to compare prices near you.

What Is Triple Antibiotic Ointment?

Triple antibiotic ointment is an over-the-counter first aid product that combines three antibiotics — bacitracin zinc, neomycin sulfate, and polymyxin B sulfate — in a single topical ointment. Each of the three ingredients works against a different, overlapping range of bacteria commonly found on skin, which is why they're combined rather than used alone.

Per the FDA over-the-counter monograph, it's labeled as first aid to help prevent infection in minor cuts, scrapes, and burns. A small amount (about the size of the tip of a finger) is applied to the affected area one to three times a day, and the area can be covered with a sterile bandage.

Saving Money on Triple Antibiotic Ointment

Because this is an over-the-counter monograph product, it's made by many manufacturers, and store-brand versions contain the same active ingredients at the same strengths as name-brand products like Neosporin Original. Prices still vary by pharmacy and package size, so it's worth comparing before you buy, particularly if you keep it stocked as a first aid staple. An Rx.com coupon can help even on an OTC product at pharmacies where it's rung up as a covered item.

Alternatives and Comparisons

  • Neosporin Original – the best-known name brand containing the same three antibiotics (neomycin, polymyxin B, and bacitracin zinc).
  • Bacitracin ointment (single-ingredient) – often chosen by people who are sensitive or allergic to neomycin, which is a more common cause of contact dermatitis than the other two ingredients.
  • Plain petroleum jelly – some dermatologists recommend it instead of antibiotic ointment for routine minor wound care to reduce the chance of developing an antibiotic allergy over time; ask your provider what's appropriate for your situation.

Safety Information

Triple antibiotic ointment is for external use only — it should not be used in the eyes, over large areas of the body, or for longer than a week without checking with a doctor. Ask a doctor before using it on deep or puncture wounds, animal bites, or serious burns. Stop use and ask a doctor if the condition doesn't improve within a week, gets worse, or if a rash or other allergic reaction develops; neomycin in particular is a relatively common cause of allergic contact dermatitis with repeated use. This is not a controlled substance and is not known to interact with oral medications when used as directed on intact or minor skin injuries, but check with a pharmacist if you have questions.

Sources & accuracy

This Triple Antibiotic information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Triple Antibiotic on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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