Zilactin
Zilactin 7.1GM of 10%
What is Zilactin?
Zilactin is an over-the-counter medication used primarily for the treatment of oral ulcers, such as canker sores and cold sores. It forms a protective barrier over the sore to reduce pain and promote healing, and its active ingredient, benzyl alcohol, offers temporary relief from discomfort. This gel is applied within the mouth directly to the ulcer and can provide relief for up to 6 hours.Side Effects
- Temporary stinging or burning sensations upon application
- Numbness or tingling in the area where applied
- Allergic reactions like rash, itching, or swelling around the mouth
Warnings
- Avoid contact with eyes; if product gets in the eyes, rinse with water immediately
- Do not use for more than 7 consecutive days unless directed by a healthcare provider
- Not recommended for children under 12 years of age without the advice of a healthcare provider
- Discontinue use and consult a healthcare provider if symptoms worsen or do not improve after 7 days of use
- Do not use if you have a history of allergic reaction to any component of the product
Prescription savings · · · ·
What is Zilactin ?
Zilactin is an over-the-counter medication used primarily for the treatment of oral ulcers, such as canker sores and cold sores. It forms a protective barrier over the sore to reduce pain and promote healing, and its active ingredient, benzyl alcohol, offers temporary relief from discomfort. This gel is applied within the mouth directly to the ulcer and can provide relief for up to 6 hours.- Temporary stinging or burning sensations upon application
- Numbness or tingling in the area where applied
- Allergic reactions like rash, itching, or swelling around the mouth
- Avoid contact with eyes; if product gets in the eyes, rinse with water immediately
- Do not use for more than 7 consecutive days unless directed by a healthcare provider
- Not recommended for children under 12 years of age without the advice of a healthcare provider
- Discontinue use and consult a healthcare provider if symptoms worsen or do not improve after 7 days of use
- Do not use if you have a history of allergic reaction to any component of the product
Zilactin Coupons & Prices
Zilactin 7.1GM of 10%
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Zilactin is an over-the-counter gel used for temporary relief of cold sore and canker sore pain, and you don't need a prescription to buy it — but a Zilactin coupon from Rx.com can still help you compare prices before you check out, since OTC products can vary in cost from pharmacy to pharmacy. Enter your ZIP above to see today's price nearby.
What Is Zilactin and How Does It Work?
Zilactin is the brand name for a line of topical oral gels made by Blairex Laboratories. The original Zilactin and Zilactin Early Relief Cold Sore products use benzyl alcohol 10% as the active ingredient, a local anesthetic that also helps the gel dry into a protective film that stays over the sore. A related product, Zilactin-B, instead uses benzocaine 10%, a different local anesthetic. Both are FDA over-the-counter monograph products, meaning they follow a standard OTC formula rather than requiring individual FDA approval, and generic versions of these ingredients are available.
Per the product labeling, Zilactin products are indicated for temporary relief of pain from cold sores and fever blisters, canker sores, minor mouth and gum sores and irritations, and irritation caused by dentures or braces. The gel is applied directly to the affected area, where it dries and forms a barrier over the lesion.
How to Save on Zilactin
Zilactin is sold without a prescription, so most people buy it directly off the shelf or online. Even so, OTC prices differ by pharmacy and retailer, so it's worth comparing before you buy. Enter your ZIP above to see today's price at pharmacies near you, and check whether a Rx.com coupon lowers the price at a particular location. Prices vary by pharmacy, so it pays to compare rather than assume one store is always cheapest.
Zilactin vs. Other Cold Sore and Canker Sore Treatments
Zilactin isn't the only over-the-counter option for mouth sores. Docosanol (sold as Abreva) works differently — it's an antiviral cream aimed specifically at cold sores rather than a numbing agent. Orajel products, like Zilactin-B, typically rely on benzocaine as the active ingredient for numbing mouth and gum pain. Because these products use different active ingredients and are meant for slightly different situations, it's reasonable to compare labels and talk to a pharmacist if you're unsure which fits your symptoms.
Safety Information
Zilactin products are for external and oral mucosal use only. According to the label, you should avoid applying it to healthy surrounding skin or gums, and should not use it for longer than 7 days without seeing a doctor. It is not intended for children under 2 years old, and all products should be kept out of the reach of children. The gel is flammable due to its SD alcohol content, so avoid open flame or heat and don't smoke until it has dried on the skin.
Zilactin-B and other benzocaine-containing products carry an FDA warning about a rare but serious condition called methemoglobinemia, which has occurred more often in young children. If your sore doesn't improve within 7 days, or if it gets worse, stop use and contact your doctor. This information is not a substitute for medical advice — talk to your doctor or pharmacist if you have questions about whether this product is right for you.
This Zilactin information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Zilactin on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.