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Baclofen

Baclofen 10MG

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¿Qué es Baclofen?

El baclofeno es un relajante muscular de acción central comúnmente recetado para aliviar la espasticidad en condiciones como la esclerosis múltiple, lesiones de la médula espinal y otros trastornos neurológicos. Funciona activando los receptores GABA-B, los cuales inhiben los neurotransmisores excitatorios que causan espasmos musculares, reduciendo así la rigidez muscular y mejorando la movilidad.

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¿Qué es Baclofen ?

El baclofeno es un relajante muscular de acción central comúnmente recetado para aliviar la espasticidad en condiciones como la esclerosis múltiple, lesiones de la médula espinal y otros trastornos neurológicos. Funciona activando los receptores GABA-B, los cuales inhiben los neurotransmisores excitatorios que causan espasmos musculares, reduciendo así la rigidez muscular y mejorando la movilidad.

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Baclofen 10MG

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Licensed US providers · Online visit in minutes
Baclofen Vial — prescription drug image
Prescription
Baclofen 20ml of 40mg/20ml (2)
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What Is Baclofen?

Baclofen is a prescription centrally acting skeletal muscle relaxant approved for the treatment of spasticity resulting from multiple sclerosis, spinal cord injuries, and other spinal cord diseases. It is also available in an intrathecal formulation for severe spasticity unresponsive to oral therapy, though oral baclofen is the most common form.

What Does Baclofen Treat?

  • Spasticity from multiple sclerosis (MS) — reduces painful muscle stiffness and spasms
  • Spinal cord injury spasticity — improves mobility and quality of life
  • Other spinal cord pathologies — e.g., ALS, cerebral palsy (off-label)
  • Alcohol use disorder — increasingly used off-label to reduce cravings and withdrawal symptoms

How Does Baclofen Work?

Baclofen is a GABA-B receptor agonist. By activating GABA-B receptors in the dorsal horn of the spinal cord, baclofen reduces the release of excitatory neurotransmitters like glutamate and substance P, suppressing the hyperexcitable motor pathways that produce involuntary muscle contractions and spasms.

Dosage Overview

  • Starting dose: 5 mg three times daily
  • Titration: Increase by 5 mg per dose every 3 days as needed
  • Typical effective range: 40–80 mg/day (in divided doses)
  • Maximum dose: 80 mg/day

Never stop baclofen abruptly — sudden discontinuation can cause serious withdrawal including seizures, hallucinations, and high fever. Always taper under medical supervision.

Side Effects

Common side effects include drowsiness, dizziness, weakness, nausea, and confusion — especially at higher doses. Sedation often improves as the body adjusts. Avoid alcohol during baclofen therapy.

Save on Baclofen

Generic baclofen is very inexpensive. With a free Rx.com coupon, a 30-day supply can cost as little as $10–$20.

Get Evaluated for Spasticity or Muscle Spasms Online

See a provider online through Rx.com to discuss your symptoms and whether baclofen is an appropriate treatment for you.

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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