Impact-Site-Verification: 2721d812-1059-4270-b9fa-5c1654788cd1

Xiidra

Xiidra

Xiidra

See your results below for

Xiidra : Solution - 30

Prescription savings · ·

  • Eye irritation
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Changes in vision
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or other eye problems.

Xiidra Coupons & Prices

Xiidra

What is Xiidra ?

Xiidra coupons can help reduce the cost of this prescription treatment for dry eye disease. Xiidra (lifitegrast ophthalmic solution) is commonly prescribed to help relieve dry, irritated eyes caused by chronic inflammation. Explore Rx.com's Xiidra savings cards, manufacturer coupons, pharmacy discounts, insurance coverage options, and other ways to lower your prescription costs. Compare Xiidra prices, find available discounts, and learn how to save on your next refill. If you need a prescription or a refill for Xiidra, Rx.com can connect you with a physician online in minutes.

See prices near you Compare 60,000+ US pharmacies · save up to 90%
Xiidra pill image

Prescriptions & Refills

Get this medication and other prescriptions or refills online with same-day video visits — sent straight to your pharmacy. HSA & FSA-eligible.

Prescription
Xiidra 5% (30)
43215 · Change ZIP
43215 Change ZIP
Prices change often. Get notified when Xiidra drops in price.
Set Up Price Alerts

Looking for a Xiidra coupon? Xiidra (lifitegrast) is a brand-name prescription eye drop used to treat the signs and symptoms of dry eye disease. As a brand-name medicine with no generic, the cash price often runs $600 or more for a one-month supply without insurance, though it varies by pharmacy. A free Rx.com Xiidra coupon lets you compare cash prices at more than 60,000 U.S. pharmacies and show the coupon at the counter — no membership, no signup, and nothing to pay Rx.com. Enter your ZIP code above to see today's lowest Xiidra price near you.

What is Xiidra (lifitegrast) and how does it work?

Xiidra is the brand name for lifitegrast, a prescription eye drop that targets inflammation on the surface of the eye. By calming this inflammation, Xiidra helps relieve both the signs (what a doctor can see) and the symptoms (what you feel) of dry eye disease.

It is prescribed for adults with dry eye disease and is typically used as one drop in each eye twice a day, about 12 hours apart. Contact lenses should be removed before using the drops.

How much does Xiidra cost without insurance?

Xiidra is a brand-name drug with no generic version available, which is the main reason the cash price is high. Prices also vary by pharmacy and location — the same prescription can differ by a wide margin between two pharmacies in the same town. That price gap is exactly why comparing pharmacies with a coupon matters. Enter your ZIP code above to see live cash prices near you and pull up a free coupon for the lowest one.

Xiidra coupon vs. the manufacturer savings card

The maker of Xiidra offers a savings program, but manufacturer copay cards are generally limited to patients with commercial (private) insurance and typically exclude people with Medicare, Medicaid, or no insurance. If you are paying cash or your plan does not cover Xiidra, a free Rx.com discount coupon is often the more useful option because anyone can use it regardless of insurance status. Compare the manufacturer terms against the Rx.com cash price above to see which is lower for you.

Xiidra vs. Restasis and other dry eye treatments

Xiidra is one of a few prescription treatments for chronic dry eye disease. Restasis and Cequa (cyclosporine) are other prescription drops that work through a different mechanism. Many people also use over-the-counter artificial tears for added comfort. Each option has different dosing and cost, so the right choice is a decision for you and your eye doctor. If you are prescribed a different dry eye medicine, you can pull up a free Rx.com coupon for it the same way.

Important Xiidra safety information

The most common side effects of Xiidra include eye irritation, an unusual taste in the mouth right after using the drops, and blurred vision. Wait at least 15 minutes after using Xiidra before putting contact lenses back in. This information is educational and is not a substitute for medical advice — always follow your doctor and pharmacist's instructions.

Frequently Asked Questions About Xiidra

Is there a Xiidra coupon?
Yes. Rx.com offers a free Xiidra coupon you can use at more than 60,000 U.S. pharmacies. There is no membership or signup — search Xiidra, enter your ZIP code, choose the lowest price near you, and show the coupon to your pharmacist to get the discounted cash price.
What is Xiidra used for?
Xiidra (lifitegrast) is a prescription eye drop used to treat the signs and symptoms of dry eye disease in adults. It is usually used twice a day, about 12 hours apart — always follow your doctor's instructions.
Is there a generic version of Xiidra?
No. There is currently no generic version of Xiidra (lifitegrast) available in U.S. pharmacies, which is part of why the cash price is high. A free Rx.com coupon helps you find the lowest available cash price for the brand near you.
What is Xiidra used for?
Xiidra coupons can help reduce the cost of this prescription treatment for dry eye disease. Xiidra (lifitegrast ophthalmic solution) is commonly prescribed to help relieve dry, irritated eyes caused by chronic inflammation. Explore Rx.com's Xiidra savings cards, manufacturer coupons, pharmacy discounts, insurance coverage options, and other ways to lower your prescription costs. Compare Xiidra prices, find available discounts, and learn how to save on your next refill. If you need a prescription or a refill for Xiidra, Rx.com can connect you with a physician online in minutes.
How much does Xiidra cost without insurance?
The price of Xiidra without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Xiidra?
Common side effects of Xiidra may include: Eye irritation, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Changes in vision. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Xiidra?
Generic versions may be available for Xiidra. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Xiidra on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Xiidra?
The cheapest pharmacy for Xiidra depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Xiidra near you.
¿Buscando esta página en español?


Don't Miss Out On Savings!


Rx.com does not warrant the accuracy of the information on this website. All information on this site is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of a drug is safe, appropriate, or effective for you. Consult your healthcare professional before using any drug. All logos, brand names and trademarks on this website are the property of their respective owners. Rx.com is not endorsed or affiliated with any brands represented on this website."

Pharmacy discounts are Not Insurance, and are Not Intended as a Substitute for Insurance THE DISCOUNT IS ONLY AVAILABLE AT PARTICIPATING PHARMACIES As an Amazon Associate, we earn from qualifying purchases.

2026 All Rights Reserved | Rx.com®