Clobetasol 17 Propionate
Clobetasol
What is Clobetasol 17 Propionate?
Clobetasol propionate is a highly potent topical corticosteroid that is used to treat a variety in inflammatory and immune-responsive dermatosis. Available in various forms such as creams, ointments, and shampoos, it effectively reduces swelling, redness, and itching by suppressing immune responses and inflammation. It is typically prescribed for severe dermatological conditions like psoriasis and eczema when less potent treatments are ineffective.
Side Effects
- Burning, itching, or irritation at the application site
- Skin dryness
- Redness or scaling of the skin
Warnings
- Do not use this medication on your face, groin, or underarms unless directed to do so by your doctor.
- Use this medication only for the condition for which it was prescribed. Do not use for longer than prescribed.
- Avoid contact with eyes. If the medication gets in the eyes, rinse thoroughly with water.
- Inform your doctor if your condition persists or worsens after 2 weeks of treatment.
- Use caution in children, as they may be more sensitive to the effects of corticosteroids.
Prescription savings · · · ·
What is Clobetasol 17 Propionate ?
Clobetasol propionate is a highly potent topical corticosteroid that is used to treat a variety in inflammatory and immune-responsive dermatosis. Available in various forms such as creams, ointments, and shampoos, it effectively reduces swelling, redness, and itching by suppressing immune responses and inflammation. It is typically prescribed for severe dermatological conditions like psoriasis and eczema when less potent treatments are ineffective.
- Burning, itching, or irritation at the application site
- Skin dryness
- Redness or scaling of the skin
- Acne
- Changes in skin color
- Folliculitis
- Stretch marks
- Skin thinning and easy bruising
- Do not use this medication on your face, groin, or underarms unless directed to do so by your doctor.
- Use this medication only for the condition for which it was prescribed. Do not use for longer than prescribed.
- Avoid contact with eyes. If the medication gets in the eyes, rinse thoroughly with water.
- Inform your doctor if your condition persists or worsens after 2 weeks of treatment.
- Use caution in children, as they may be more sensitive to the effects of corticosteroids.
- May cause adrenal suppression with long-term use or use over large areas of the body.
- May increase the risk of systemic side effects when used over large areas of the body or with occlusive dressings.
Clobetasol 17 Propionate Coupons & Prices
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Clobetasol 17 Propionate prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 0.5gm of · Bottle | 120 | — | $53,777.40 |
| 1gm of · Bottle | 120 | — | $53,777.40 |
| 1gm of 0.5% · Bottle | 1 | $83.18 | $53.04 |
| 5gm of · Bottle | 120 | — | $53,777.59 |
| 10gm of · Bottle | 120 | — | $53,777.59 |
| 100gm of · Bottle | 120 | — | $53,777.59 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
A clobetasol-17-propionate coupon from Rx.com can lower what you pay at the pharmacy counter when you are paying cash. Clobetasol propionate is the generic form of a super-high-potency topical steroid sold under brand names such as Temovate, Clobex, Olux, and Cormax. Cash prices for the same tube, bottle, or can can differ a lot from one pharmacy to the next, even across town, so it pays to compare before you fill. Rx.com compares prices at more than 60,000 pharmacies. Enter your ZIP code above to see today's price near you and print, text, or email your free coupon.
What is clobetasol propionate and how does it work?
Clobetasol propionate is a topical corticosteroid, and it sits in the strongest group dermatologists use: Class I, sometimes called super-high-potency or ultra-potent. Applied to the skin, it calms the inflammation and itching that drive many skin conditions. It is not a cream you use casually or long-term, and it is not for oral, eye, or vaginal use.
It comes in several forms, and the FDA-approved uses are specific to each one. The cream, ointment, and gel are approved to relieve the inflammatory and itchy symptoms of corticosteroid-responsive skin conditions in people 12 and older. The lotion is approved for the same purpose, relief of the inflammatory and itchy symptoms of corticosteroid-responsive skin conditions, but only in adults 18 and older. The spray is approved for moderate-to-severe plaque psoriasis covering up to 20% of the body in adults 18 and older. The shampoo is approved for moderate-to-severe scalp psoriasis in adults 18 and older.
The two foams are not interchangeable, and their labels do not say the same thing. Olux foam is approved for short-term treatment of the inflammatory and itchy symptoms of moderate-to-severe corticosteroid-responsive skin conditions of the scalp, and for short-term treatment of mild-to-moderate plaque-type psoriasis on non-scalp areas, excluding the face and skin folds. Olux-E, the emollient foam, is approved more broadly for corticosteroid-responsive skin conditions in patients 12 and older, and is not scalp-specific. Your prescriber chooses the form that fits where the problem is and how thick the skin there is.
What clobetasol propionate costs without insurance, and how a coupon helps
Clobetasol propionate is available as an FDA-approved generic, so most people paying cash are filling the generic rather than a brand. That does not mean every pharmacy charges the same thing. Cash prices for topical steroids swing widely by pharmacy and by form, and the size you are prescribed matters too, since a 15-gram tube and a 60-gram tube are very different purchases. The spray, shampoo, foam, and lotion forms are typically priced quite differently from plain cream or ointment.
Because of that spread, comparing is the whole game. A discount coupon like Rx.com's is not insurance. It is a cash-price program you can use when you have no coverage, when your plan does not cover this drug, or when the cash price simply beats your copay. There is no manufacturer savings card for generic clobetasol propionate. Enter your ZIP above to see today's price at pharmacies near you, then bring the coupon with your prescription. Ask the pharmacist to run the coupon before you pay, and always check whether your insurance copay is the better deal, because sometimes it is.
Brands and related topical steroids
Clobetasol propionate is the active ingredient behind several brands, and if your prescription names one of them, the price picture may look different from generic. Temovate (cream and ointment), Clobex (lotion, shampoo, and spray), and Olux and Olux-E (foam) are all clobetasol propionate. Other brand names built on the same ingredient include Impoyz (a 0.025% cream) and Tovet. You may also run across older brand names for clobetasol propionate, such as Temovate E, Cormax, Embeline, and Embeline E, in past prescriptions, pharmacy records, or reference books. Not all of these are still marketed in the United States, so check with your pharmacist about what is actually stocked before you shop on a brand name. Impoyz, the lotion, the spray, and the shampoo are not for use under age 18.
If clobetasol is stronger than what you need, or your provider wants to step you down after a short course, other topical steroids of different potencies are commonly used instead. Halobetasol propionate is another very strong option. Betamethasone dipropionate and fluocinonide are step-down choices, triamcinolone acetonide is a mid-strength workhorse, and hydrocortisone is the mildest tier and the one often used on delicate areas. Only your prescriber should decide which potency belongs on which patch of skin. If you do switch, compare the cash price on the new drug too, since the ranking changes by pharmacy.
Safety: what to know before you use it
Clobetasol propionate has no boxed warning, but its strength is exactly why the label sets firm limits. Enough of it can get through the skin into the bloodstream to suppress the body's own cortisol system (called HPA-axis suppression), which is usually reversible but can lead to Cushing's syndrome, high blood sugar, and sugar in the urine. The label says not to exceed 50 grams (or 50 mL) per week, and treatment is generally limited to 2 consecutive weeks.
A few forms carry their own duration language beyond that 2-week rule. With the lotion, very localized moderate-to-severe plaque psoriasis lesions covering no more than 10% of the body that have not improved enough after the first 2 weeks may be treated for up to 2 additional weeks; the lotion's label also reports that 8 of 10 evaluable patients with moderate-to-severe plaque psoriasis had adrenal suppression after 4 weeks of treatment, which is a real illustration of why the cap exists. The spray may be used up to 4 weeks, with caution beyond 2. The shampoo has its own limits as well. Do not extend any of these on your own.
Do not cover the treated skin with an airtight (occlusive) dressing, and do not apply it to the face, underarms, or groin. Children absorb proportionally more because they have more skin surface relative to body size, so they face greater risk of HPA suppression and effects on growth; the cream and ointment are not recommended under age 12, and the lotion, spray, shampoo, and Impoyz are not for anyone under 18.
More common problems stay in the skin: thinning (atrophy), stretch marks, tiny visible blood vessels, burning or stinging, folliculitis, acne-like bumps, loss of skin color, rash around the mouth, and allergic reactions. Do not use it on an untreated bacterial, fungal, or viral skin infection, since it can let an infection spread. Use near the eyes carries a risk of glaucoma and cataracts, and getting it in the eye should be avoided. Stop and call your provider if irritation develops. If your provider finds HPA suppression, they will taper you off or cut back the frequency rather than have you quit cold. This is general information, not medical advice. Talk with your doctor or pharmacist about your own situation, and follow the directions on your prescription.
This Clobetasol 17 Propionate information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Clobetasol 17 Propionate on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.