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Dorzolamide Hcl Bottle — prescription drug image

Dorzolamide Hcl

Dorzolamide HCl 10ML of 2%

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What is Dorzolamide Hcl?

Trusopt is used to lower increased pressure in the eye. Dorzolamide Ophthalmic is the generic version of Trusopt. The average Trusopt cost is about $127 for a supply of 10, 2% ophthalmic solution. Luckily, you can significantly reduce the Trusopt price by using our free Singlecare coupon card at participating local pharmacies.

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What is Dorzolamide Hcl ?

Trusopt is used to lower increased pressure in the eye. Dorzolamide Ophthalmic is the generic version of Trusopt. The average Trusopt cost is about $127 for a supply of 10, 2% ophthalmic solution. Luckily, you can significantly reduce the Trusopt price by using our free Singlecare coupon card at participating local pharmacies.
  • Mild eye discomfort or feeling that something is in your eye
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, or red skin rash
  • Red, itchy, or swollen eyelids or eyes
  • Dry eyes
  • Eye sensitivity to sunlight
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, an eye infection, or other eye problems (including a history of eye surgery). Tell your doctor if you are allergic to sulfa drugs.
  • This medicine may cause serious allergic eye or skin reactions.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
What is dorzolamide eye drops used for?
Dorzolamide 2% ophthalmic solution is FDA-approved to lower elevated pressure inside the eye in people with ocular hypertension or open-angle glaucoma. The usual labeled dose is one drop in the affected eye or eyes three times a day. It controls glaucoma rather than curing it, so it is normally continued long term. It is often used alongside another drop, such as a prostaglandin analog or a beta-blocker.
How will I know if dorzolamide is working?
Not by how your eyes feel. Dorzolamide works by reducing fluid production inside the eye, and high eye pressure usually causes no symptoms at all, so there is nothing you will notice when it is working. Your eye doctor is the one who tracks it, by measuring your eye pressure at follow-up visits. In the clinical studies described in the labeling, the drop lowered intraocular pressure by approximately 3 to 5 mmHg throughout the day, and that effect held up in trials lasting as long as a year. Keep using the drops exactly as prescribed and keep your appointments so your doctor can check whether your pressure is where it should be.
What are the most common side effects of dorzolamide eye drops?
The most common are burning, stinging, or discomfort in the eye, reported by about one third of people, and a bitter taste, reported by about one quarter. Superficial punctate keratitis (small spots of irritation on the surface of the eye) occurs in roughly 10 to 15 percent, and signs of eye allergy in about 10 percent. Contact your doctor promptly about any serious or allergic-type reaction. This is not a complete list of side effects, so ask your pharmacist or read the label that comes with your prescription.
Can you use dorzolamide if you are allergic to sulfa drugs?
Dorzolamide is a sulfonamide, and even though it goes in the eye, some of it is absorbed into the body. The serious reactions attributed to sulfonamides have been reported with it, including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, and aplastic anemia. Tell your doctor and pharmacist about any sulfa allergy before you start, and stop the drops and get medical help at the first sign of a serious reaction or hypersensitivity. Only your prescriber can decide whether it is appropriate for you.
Is dorzolamide the same as Trusopt or Cosopt?
Trusopt was the brand name for dorzolamide alone, but the brand is no longer marketed in the U.S.; the FDA-approved generic 2% ophthalmic solution is what pharmacies dispense today. Cosopt and Cosopt PF are different products: they combine dorzolamide with timolol, a beta-blocker, in one bottle. So dorzolamide and Cosopt are not interchangeable. Fill exactly what your prescription says, and check the price on that specific product.
How much does Dorzolamide Hcl cost without insurance?
The price of Dorzolamide Hcl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Dorzolamide Hcl?
Common side effects of Dorzolamide Hcl may include: Mild eye discomfort or feeling that something is in your eye, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Blistering, peeling, or red skin rash, Red, itchy, or swollen eyelids or eyes, Dry eyes. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Dorzolamide Hcl?
Generic versions may be available for Dorzolamide Hcl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Dorzolamide Hcl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Dorzolamide Hcl?
The cheapest pharmacy for Dorzolamide Hcl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Dorzolamide Hcl near you.

Dorzolamide Hcl Coupons & Prices

Dorzolamide HCl 10ML of 2%

Prescriptions & Refills
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Dorzolamide Hcl Bottle — prescription drug image
Prescription
Dorzolamide Hcl 10ml of 2% (1)
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A dorzolamide HCl coupon from Rx.com can lower what you pay out of pocket for dorzolamide hydrochloride 2% ophthalmic solution, the generic eye drop used to lower high eye pressure in open-angle glaucoma and ocular hypertension. Cash prices for the same bottle can differ a lot from one pharmacy to the next, even across the street from each other, so comparing before you fill is worth the minute it takes. Enter your ZIP code above to see today's price at pharmacies near you, then show the free coupon at the counter. No insurance is needed.

What is dorzolamide HCl and how does it work?

Dorzolamide hydrochloride is a topical (ophthalmic) carbonic anhydrase inhibitor, a sulfonamide-derived anti-glaucoma medicine. It is FDA-approved to treat elevated intraocular pressure (the pressure inside the eye) in people with ocular hypertension or open-angle glaucoma. It comes as a 2% eye drop solution (20 mg/mL of dorzolamide, equal to 22.3 mg/mL of dorzolamide hydrochloride). The usual labeled dose is one drop in the affected eye or eyes three times a day.

Dorzolamide controls glaucoma but does not cure it, so it is normally used long term, for as long as your eye doctor says. Many people take it as an add-on to another drop such as a prostaglandin analog or a beta-blocker, and it is also widely prescribed as a fixed-dose combination with timolol. Your eye pressure can be high without any symptoms at all, which is why keeping up with the drops and your eye exams matters even when your eyes feel fine.

What dorzolamide eye drops cost without insurance

Dorzolamide 2% ophthalmic solution is available as an FDA-approved generic, and the brand it copies, Trusopt, is no longer marketed in the U.S. Generic dorzolamide does not have a manufacturer savings card. What you actually pay is set by the pharmacy, and cash prices for the identical bottle vary widely from one store to another, so the pharmacy you happen to use is often the biggest factor in your bill.

That is what a coupon is for. Rx.com compares prices across more than 60,000 pharmacies, including the big chains, grocery and warehouse pharmacies, and independents, so you can see who is cheapest near you before you drive over. Enter your ZIP code above to see today's price, print or show the coupon on your phone, and hand it to the pharmacist with your prescription. You do not need insurance to use it, and it is free. If you do have insurance, it is still worth checking the cash price with a coupon against your copay, since sometimes the coupon price is lower. You cannot combine the two on one fill.

Dorzolamide alternatives and related glaucoma drops

Dorzolamide is one of several options for lowering eye pressure, and eye doctors often combine drops from different classes. Related medicines you may see include:

  • dorzolamide/timolol and its brand Cosopt (also Cosopt PF) - dorzolamide combined with a beta-blocker in one bottle, which cuts down on the number of drops per day
  • timolol maleate - a beta-blocker eye drop
  • latanoprost - a prostaglandin analog, often used once daily
  • brimonidine tartrate - an alpha agonist drop
  • brinzolamide - another topical carbonic anhydrase inhibitor
  • acetazolamide - a carbonic anhydrase inhibitor taken by mouth, not a drop. It is not recommended to use an oral carbonic anhydrase inhibitor at the same time as dorzolamide, because the systemic effects add up.

Which one is right depends on your eye pressure, your other health conditions, and how well you tolerate each drop. That is a conversation for your eye doctor, not a swap to make on your own. Prices differ between these products and between pharmacies, so check the price on whichever one you are actually prescribed.

Safety, side effects, and how to use the drops

Dorzolamide has no boxed warning. The most important thing to know is that it is a sulfonamide, and even though you put it in your eye, some of it is absorbed into the body. The same serious reactions linked to sulfonamide drugs have been reported, including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood problems. Stop the drops and contact your doctor at the first sign of a serious reaction or an allergic reaction. Dorzolamide is not recommended if you have severe kidney impairment (creatinine clearance under 30 mL/min), because it is cleared by the kidneys, and it should be used with caution in liver impairment. Corneal swelling has been reported in people with low corneal endothelial cell counts, and choroidal detachment has been reported after filtering surgery.

The most common side effects are burning, stinging, or general discomfort in the eye (about one in three people), a bitter taste (about one in four), superficial punctate keratitis (10 to 15 percent), and signs of eye allergy (about 10 percent). To use the drops safely: do not let the dropper tip touch your eye or any surface, since contaminated multi-dose bottles have been linked to bacterial keratitis; take soft contact lenses out before instilling and wait 15 minutes before putting them back in, because of the benzalkonium chloride preservative; and if you use more than one topical eye drop, the labeling says to space them at least 5 minutes apart. This page is information, not medical advice. Talk with your eye doctor or pharmacist about your own situation, and tell them about every other medicine and drop you use.

Sources & accuracy

This Dorzolamide Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Dorzolamide Hcl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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