Dorzolamide Hcl-Timolol Mal Coupons & Prices

Use the free Rx.com dorzolamide-hcl-timolol-mal coupon to compare cash prices on dorzolamide hydrochloride / timolol maleate ophthalmic solution (2%/0.5%), the generic of Cosopt, at more than 60,000 pharmacies nationwide. This twice-daily eye drop combines two glaucoma medicines in one bottle and is FDA-approved to lower elevated pressure inside the eye in people with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. Cash prices for the same prescription can vary a lot from one pharmacy to the next, even within the same town, so enter your ZIP above to see today's price near you. No insurance is needed to use the coupon.

What is dorzolamide-timolol, and how does it work?

Dorzolamide hydrochloride / timolol maleate ophthalmic solution is a fixed-combination eye drop that pairs two different pressure-lowering medicines. Dorzolamide is a topical carbonic anhydrase inhibitor (and a sulfonamide), and timolol is a non-selective topical beta-adrenergic blocker. Both reduce the amount of fluid the eye produces, and combining them in one bottle lowers intraocular pressure (IOP) more than either agent does on its own. It is sold under the brand names Cosopt and Cosopt PF.

The FDA-approved use is the reduction of elevated IOP in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. The usual dose on the label is one drop in the affected eye or eyes twice daily; if you use more than one eye drop, the label says to space them at least five minutes apart. Some eye doctors also use this combination at other points in treatment, including after a prostaglandin drop such as latanoprost — that is a practice pattern outside the labeled population described above, not an FDA-approved use. Your prescriber decides whether this combination is right for your eyes.

Dorzolamide-timolol cost without insurance, and how the coupon works

An AB-rated generic of this exact eye drop is FDA-approved and marketed in the United States, and the generic is typically what gets dispensed. Whether your pharmacy can substitute it for brand Cosopt depends on your state's substitution law and on how the prescription is written, so ask the pharmacist if you are unsure. Either way, that does not mean every pharmacy charges the same. Cash prices for the identical bottle can differ widely between chains, grocery pharmacies, and independents, which is exactly why comparing before you fill is worth the minute it takes. Enter your ZIP code above to see today's price at pharmacies near you.

The Rx.com coupon is free, requires no insurance, and is accepted at more than 60,000 pharmacies. Show it to the pharmacist at drop-off, before they run the claim. A coupon is a cash-price discount and cannot be combined with insurance on the same fill, so if you have coverage it is worth asking the pharmacist to compare your copay against the coupon price and simply run whichever is lower. Manufacturer savings cards are generally offered for brand products rather than generics, so one is unlikely to apply here; brand programs, when they exist, are run by the manufacturer's own official website and their terms vary and change over time.

Alternatives and related glaucoma eye drops

Dorzolamide-timolol is one of several options for lowering eye pressure, and the right one depends on your eyes, your other medical conditions, and how well you tolerate each drop. Related medicines your eye doctor may discuss include:

• Dorzolamide alone or timolol alone, if you only need one of the two ingredients
• Prostaglandin analog drops such as latanoprost, travoprost, or bimatoprost
• Brinzolamide, another topical carbonic anhydrase inhibitor
• Brimonidine, an alpha agonist drop

If cost is the reason you are considering a switch, compare prices on your current drop first. Never stop or change a glaucoma medicine on your own, because elevated pressure usually causes no symptoms while it is damaging the optic nerve. Talk to your eye doctor before making any change.

Safety, side effects, and who should not use it

This eye drop has no boxed warning, but the timolol in it is absorbed into the bloodstream and can cause the same breathing and heart effects as a beta-blocker taken by mouth, including bronchospasm (fatal cases have been reported in people with asthma), slow heart rate, heart block, and worsening heart failure. Because of that, it is contraindicated in people with bronchial asthma or a history of it, severe COPD, sinus bradycardia, second- or third-degree AV block, overt cardiac failure, cardiogenic shock, or hypersensitivity to any ingredient. Dorzolamide is a sulfonamide, so serious systemic sulfonamide reactions can occur, including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood disorders. Stop the drops and contact your doctor at the first sign of a serious reaction.

Other cautions on the label: it may mask the warning signs of low blood sugar in people with diabetes and the symptoms of an overactive thyroid; it has not been studied in severe kidney impairment (creatinine clearance under 30 mL/min) and is not recommended there; contaminated bottle tips have caused bacterial keratitis, so do not let the tip touch your eye or any surface; and there are corneal endothelium concerns in people with low endothelial cell counts. The most common effects are a bitter taste, burning or stinging in the eye, blurred vision, and eye redness. The multi-dose bottle contains benzalkonium chloride, which soft contact lenses absorb, so remove lenses before each dose and wait 15 minutes before putting them back in. This page is information only and is not medical advice; tell your prescriber and pharmacist about all your conditions and medicines.