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Fluocinolone Acetonide Scalp Bottle — prescription drug image

Fluocinolone Acetonide Scalp

Fluocinolone Acetonide Scalp 118.28ML of 0.01%

What is Fluocinolone Acetonide Scalp?

Fluocinolone acetonide scalp solution is a topical corticosteroid used to treat scalp conditions like psoriasis and seborrheic dermatitis. This medication works by reducing inflammation and itching. For more information on cost, savings, and prescription options, visit Rx.com.

Prescription savings · · · ·

What is Fluocinolone Acetonide Scalp ?

Fluocinolone acetonide scalp solution is a topical corticosteroid used to treat scalp conditions like psoriasis and seborrheic dermatitis. This medication works by reducing inflammation and itching. For more information on cost, savings, and prescription options, visit Rx.com.
  • Red or swollen skin.
  • Pus or blisters on the skin.
  • Acne.
  • Burning, itching, or peeling skin.
  • If you are pregnant or breastfeeding, talk to your doctor before using this medicine.
  • You should not use this medicine for a longer period of time than your doctor ordered.
  • Before using this medicine, let your doctor know if you have diabetes, a stomach ulcer, or tuberculosis (TB).
  • Call your doctor if your symptoms get worse, or do not clear up after 7 days of treatment.
  • You may be more likely to have side effects from this medicine if you are over 60 years of age.
What is fluocinolone acetonide scalp oil used for?
It's FDA-approved to treat psoriasis of the scalp in adults. It's sometimes used off-label for seborrheic dermatitis of the scalp as well, though that isn't its approved indication.
How do you apply fluocinolone acetonide scalp oil correctly?
Apply the oil to a wet or damp scalp, massage it in, then cover your head with a shower cap. Leave it on overnight, or for a minimum of about 4 hours, before shampooing it out. Follow your prescriber's specific directions, since they may adjust frequency for your situation.
How long can you use fluocinolone acetonide scalp oil?
Treatment is generally intended for short courses. If you're still using it after about 2 weeks without improvement, your prescriber should reassess your treatment rather than you continuing on your own.
Is fluocinolone acetonide scalp oil safe if I have a peanut allergy?
This product contains refined peanut oil (roughly 48% of the formula), so it should be used with caution, or avoided, if you have a peanut allergy. Tell your prescriber and pharmacist about any peanut allergy before starting it.
What is the difference between fluocinolone acetonide scalp oil and Derma-Smoothe/FS?
Derma-Smoothe/FS Scalp is the brand name used for this fluocinolone acetonide scalp oil. The generic fluocinolone acetonide topical oil 0.01% (scalp oil) contains the same active ingredient.
How much does Fluocinolone Acetonide Scalp cost without insurance?
The price of Fluocinolone Acetonide Scalp without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 57% off retail prices with a free Rx.com coupon.
What are the common side effects of Fluocinolone Acetonide Scalp?
Common side effects of Fluocinolone Acetonide Scalp may include: Red or swollen skin., Pus or blisters on the skin., Acne., Burning, itching, or peeling skin.. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Fluocinolone Acetonide Scalp?
Generic versions may be available for Fluocinolone Acetonide Scalp. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Fluocinolone Acetonide Scalp on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Fluocinolone Acetonide Scalp?
The cheapest pharmacy for Fluocinolone Acetonide Scalp depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Fluocinolone Acetonide Scalp near you.

Fluocinolone Acetonide Scalp Coupons & Prices

Fluocinolone Acetonide Scalp 118.28ML of 0.01%

Fluocinolone Acetonide Scalp Bottle — prescription drug image
Prescription
Fluocinolone Acetonide Scalp 118.28ml of 0.01% (1)
your area ·

If you're comparing a fluocinolone acetonide scalp oil coupon before you fill this prescription, here's what's worth knowing: generic pricing still swings widely from one pharmacy to the next. Rx.com compares prices for fluocinolone acetonide scalp oil across 60,000+ U.S. pharmacies, so instead of assuming your usual drugstore has the best deal, you can enter your ZIP above to see today's price nearby before you check out.

What is fluocinolone acetonide scalp oil, and how does it work?

Fluocinolone acetonide topical oil 0.01% (scalp oil) is a low-to-medium potency topical corticosteroid FDA-approved to treat psoriasis of the scalp in adults. Corticosteroids like this one reduce the inflammation, redness, and scaling that come with scalp psoriasis. The oil is applied to a wet or damp scalp, massaged in, and typically covered with a shower cap and left on overnight (or for a minimum of about 4 hours) before shampooing out. It's meant for short courses — your prescriber should reassess if you're still using it after about 2 weeks.

Some prescribers also use this oil off-label for seborrheic dermatitis of the scalp, but its FDA-approved indication is specifically scalp psoriasis.

Cost without insurance, and why comparing pharmacies matters

Fluocinolone acetonide scalp oil pricing varies a lot by pharmacy, location, and pack size, so paying the first price you're quoted can mean overpaying. Enter your ZIP above to compare fluocinolone acetonide scalp oil prices across pharmacies near you and see today's price before you fill.

Alternatives and related topical steroids

Fluocinolone acetonide scalp oil is one of several topical corticosteroids prescribers use for scalp and skin conditions, spanning different potency levels. Related options your prescriber may discuss include fluocinolone acetonide in other formulations, clobetasol propionate scalp solution (a higher-potency option), betamethasone valerate, triamcinolone acetonide, and desonide (a lower-potency option). Potency, vehicle (oil, solution, foam, cream), and approved use differ between these, so which one fits depends on your specific diagnosis — this isn't a one-size-fits-all swap, and only your provider can say which is right for you.

Safety information

This product contains refined peanut oil (about 48% of the formulation), so it should be avoided or used only with caution if you have a peanut allergy — tell your provider and pharmacist if this applies to you. Because it's used under a shower cap (an occluded application), the scalp oil is absorbed more than an uncovered product would be; with prolonged or extensive use this can, in rare cases, lead to reversible effects on the body's cortisol regulation, elevated blood sugar, or sugar in the urine, particularly in children. Avoid the face, eyes, mouth, and skin-fold areas, and don't add additional occlusive wrapping beyond the directed shower cap. Stop and contact your provider if you notice skin thinning, stretch marks, or irritation. This is general information, not medical advice — follow your prescriber's specific instructions and ask them about anything that's unclear.

Sources & accuracy

This Fluocinolone Acetonide Scalp information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Fluocinolone Acetonide Scalp on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.