Glyburide Coupons & Prices

Looking for a glyburide coupon? Glyburide is the low-cost generic form of older brand-name pills like DiaBeta, Glynase, and Micronase (most of which are no longer sold in the U.S.), and as a generic it is already one of the more affordable oral diabetes medicines. Even so, the cash price can vary a lot from one pharmacy to the next, so it pays to compare. Rx.com checks prices at more than 60,000 pharmacies so you can see today's price and print or show a free discount coupon. Enter your ZIP above to see today's price near you.

What is glyburide and how does it work?

Glyburide is a second-generation sulfonylurea, a class of oral medicine used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes. It works by prompting the pancreas to release more insulin. It is sold as a generic and was once available under the brand names DiaBeta, Glynase (Glynase PresTab), and Micronase; outside the U.S. the same drug is known as glibenclamide. Glyburide is not used for type 1 diabetes or for diabetic ketoacidosis.

It has also been used in the past to help manage gestational diabetes, but it is no longer a preferred choice for that purpose, as insulin and metformin are generally favored. Your provider decides whether glyburide is right for you.

How much does glyburide cost without insurance?

Because glyburide has been generic for years, it is typically one of the lower-cost diabetes medicines you can fill. That said, the cash price is not the same everywhere. Two pharmacies on the same street can charge very different amounts for the identical prescription, which is exactly why comparing matters before you pay.

Rx.com compares glyburide prices across more than 60,000 U.S. pharmacies and shows you a free discount coupon you can use with or without insurance. We do not list a fixed dollar figure here because prices change and are shown live for your area. Enter your ZIP above to see today's price and find the lowest option near you.

Glyburide alternatives and related medicines

Glyburide is one of several sulfonylureas and is often compared with other diabetes drugs. Some people and their doctors prefer a shorter-acting sulfonylurea such as glipizide, which tends to carry a lower risk of low blood sugar, or glimepiride. Others are treated with a different class entirely, such as metformin (usually the first-line drug for type 2 diabetes) or pioglitazone.

Glyburide is also available combined with metformin in a single pill, sold as generic glyburide-metformin. Only your provider can decide which option fits your situation, but all of these are available as generics, and Rx.com lets you compare prices on each one.

Glyburide safety and side effects

The most important risk with glyburide is hypoglycemia (low blood sugar), which can be severe or long-lasting. The risk is higher in older adults and in people with kidney or liver problems, poor nutrition, those who skip meals, or those who drink alcohol. Glyburide carries a higher risk of low blood sugar than shorter-acting sulfonylureas like glipizide, and it appears on the Beers Criteria as a medicine that is potentially inappropriate for older adults. Glyburide can also cause weight gain, and its labeling carries a special warning about a possible increased risk of cardiovascular death, based on the older University Group Diabetes Program (UGDP) study, an effect linked to the sulfonylurea class.

Glyburide should be avoided in people with G6PD deficiency (risk of hemolytic anemia) and in anyone with a sulfonylurea allergy, and it should be used with caution late in pregnancy because it can cause low blood sugar in the newborn. This is general information, not medical advice. Talk with your doctor or pharmacist about your own health, and get medical help right away if you have signs of very low blood sugar such as shaking, sweating, confusion, or fainting.