Imiquimod
Imiquimod 24 Cream
What is Imiquimod?
Imiquimod treats genital warts, actinic keratoses, and basal cell carcinoma. The brand-name version of Imiquimod is called Aldara. The average Imiquimod cost is $621 for one box of 24 packets. However, you can use our free Rx.com coupon card to save significantly on Imiquimod prices at a participating pharmacy near you.Side Effects
- Fever, chills, cough, sore throat, nausea, or muscle or joint pain
- Worsening of other skin conditions
- Severe skin reaction, including burning, pain, redness, swelling, bleeding, itching, ulcers, oozing, scabbing, blisters, or peeling
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have an autoimmune disorder or problems with your immune system.
- This medicine may cause severe swelling or other skin reactions where it is applied. It could also cause flu-like symptoms. Your doctor will tell you if you need to stop using the medicine until the reaction improves.
- This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
- Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
- Treatment for genital warts: Do not have sex during the treatment time, even if you use protection. The cream can weaken condoms and diaphragms and they could break. Imiquimod is not a cure for genital or anal warts. You may develop new warts while using the cream. The cream will not keep you from spreading genital warts to other people.
Prescription savings · · · ·
What is Imiquimod ?
Imiquimod treats genital warts, actinic keratoses, and basal cell carcinoma. The brand-name version of Imiquimod is called Aldara. The average Imiquimod cost is $621 for one box of 24 packets. However, you can use our free Rx.com coupon card to save significantly on Imiquimod prices at a participating pharmacy near you.- Fever, chills, cough, sore throat, nausea, or muscle or joint pain
- Worsening of other skin conditions
- Severe skin reaction, including burning, pain, redness, swelling, bleeding, itching, ulcers, oozing, scabbing, blisters, or peeling
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Severe swelling near the vagina
- Blistering, peeling red skin rash anywhere on your body
- Tell your doctor if you are pregnant or breastfeeding, or if you have an autoimmune disorder or problems with your immune system.
- This medicine may cause severe swelling or other skin reactions where it is applied. It could also cause flu-like symptoms. Your doctor will tell you if you need to stop using the medicine until the reaction improves.
- This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
- Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
- Treatment for genital warts: Do not have sex during the treatment time, even if you use protection. The cream can weaken condoms and diaphragms and they could break. Imiquimod is not a cure for genital or anal warts. You may develop new warts while using the cream. The cream will not keep you from spreading genital warts to other people.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Imiquimod Coupons & Prices
Imiquimod 24 Cream
4 ED medications in one dose
Sildenafil, tadalafil, PT-141 & L-Citrulline · Works in ~15 min · Lasts up to 36 hours
Looking for an imiquimod coupon? Imiquimod is the generic version of Aldara and Zyclara, a prescription topical cream that treats certain sun-damage growths, a superficial form of skin cancer, and external genital warts. Because it is already available as a low-cost generic, most people do not need a brand-name product to save. Cash prices still vary widely from one pharmacy to the next, so comparing matters. Enter your ZIP above to see today's imiquimod price and a free discount coupon accepted at more than 60,000 pharmacies nationwide.
What is imiquimod and how does it work?
Imiquimod is an immune response modifier, a topical medicine that works by stimulating your skin's own local immune system to attack abnormal or virus-infected cells. It is sold under the brand names Aldara and Zyclara, and it is FDA-approved to treat actinic keratoses (flat, scaly growths caused by sun damage) on the face and scalp, superficial basal cell carcinoma (a type of skin cancer) in adults with healthy immune systems, and external genital and perianal warts caused by HPV. Both Zyclara strengths (2.5% and 3.75%) are approved for actinic keratosis of the full face or balding scalp, while only the 3.75% strength is also approved for external genital and perianal warts.
Rather than simply removing a lesion, imiquimod prompts the immune system to do the clearing over a course of treatment. Your dermatologist or prescriber will match the strength and schedule to your specific condition. This page is for general information and is not medical advice, so follow the instructions from your own provider.
Imiquimod cost and how to save without insurance
Imiquimod is available as an FDA-approved generic, so it is usually far less expensive than the Aldara or Zyclara brand. Even so, the cash price without insurance can differ a lot depending on which pharmacy you use, the strength prescribed, and the number of packets or the tube size. That is exactly why comparing before you fill is worth it.
Rx.com checks prices across more than 60,000 pharmacies and gives you a free discount coupon you can use whether or not you have insurance. Enter your ZIP above to see today's price near you. There is no manufacturer savings card required to get a low generic price here; if you were prescribed a specific brand, you can look up the manufacturer's official website for any current brand offers, though terms vary and eligibility rules apply.
Imiquimod alternatives and related treatments
Depending on the condition being treated, your prescriber may consider other topical options. For actinic keratoses, fluorouracil and diclofenac gel are common alternatives. For external genital warts, podofilox and sinecatechins are other topical choices. Tretinoin is sometimes used for related skin concerns.
These medicines work differently and are not interchangeable, so only your provider can decide which is right for your diagnosis. If you do compare, remember that generic prices for all of these can swing widely by pharmacy, and you can price each one on Rx.com to find the best local deal.
Safety and side effects
Imiquimod does not carry a boxed warning, but strong local skin reactions at the application site are expected and common. These can include redness, flaking, scaling, itching, burning, swelling, erosion, and scabbing or ulceration. Some people notice lasting skin lightening or darkening in the treated area. Because the cream activates the immune system, it can also cause flu-like symptoms such as fatigue, fever, muscle aches, or headache.
Imiquimod increases your skin's sensitivity to sunlight, so minimize sun exposure and avoid tanning. Do not apply it to skin that has not fully healed from a prior treatment, and keep it away from the eyes, lips, nostrils, and the inside of the vagina or anus. Use with caution if you have an autoimmune condition or a weakened immune system, and wash your hands after applying. This is general information, not medical advice; talk with your provider or pharmacist about your specific situation and any other medicines you take.
This Imiquimod information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Imiquimod on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
Browse more medications: starting with I · full A-Z directory · by condition · common drugs
Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.