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Indapamide Tablet — prescription drug image

Indapamide

Indapamide 1.25MG

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What is Indapamide?

Indapamide is used to treat hypertension and control the retention of fluid in the body in patients who have congestive heart failure. Indapamide is a generic drug. The average Indapamide price is about $25 for a supply of 30 tablets, 2.5 mg tablets. You can use our Rx.com savings offer to get an Indapamide discount of up to 80% off of the retail price at participating pharmacies near you.

Prescription savings · · · ·

What is Indapamide ?

Indapamide is used to treat hypertension and control the retention of fluid in the body in patients who have congestive heart failure. Indapamide is a generic drug. The average Indapamide price is about $25 for a supply of 30 tablets, 2.5 mg tablets. You can use our Rx.com savings offer to get an Indapamide discount of up to 80% off of the retail price at participating pharmacies near you.
  • Blurred vision or changes in vision
  • Change in how much or how often you urinate
  • Blistering, peeling, red skin rash
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Lightheadedness, dizziness, or fainting
  • Fast, slow, pounding, or uneven heartbeat
  • Unusual bleeding, bruising, or weakness
  • Dry mouth, increased thirst, muscle cramps, nausea or vomiting
  • Swelling in your hands, feet, ankles, or legs, tiredness
  • Confusion, weakness, muscle twitching
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, heart rhythm problems, diabetes, lupus, gout, or trouble urinating. Tell your doctor if you had any type of surgery.
  • This medicine may cause the following problems:Eye or vision problems, including glaucoma, myopiaHigh uric acid in the bloodParathyroid gland problems
  • Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure high blood pressure, but it will help keep it in normal range. You may have to take blood pressure medicine for the rest of your life.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is indapamide used for?
Indapamide is FDA-approved to treat hypertension (high blood pressure), either by itself or combined with other blood pressure medications, and to treat salt and fluid retention (edema) associated with congestive heart failure. It works by helping the kidneys remove excess sodium and water through urine.
Is indapamide the same as hydrochlorothiazide (HCTZ)?
No. Indapamide and hydrochlorothiazide are both diuretics used for blood pressure and fluid retention, and they work in a similar way in the kidneys, but they are chemically different drugs — indapamide is classified as a thiazide-like diuretic, while HCTZ is a true thiazide. They aren't automatically interchangeable; your doctor decides which one fits your situation.
What are the side effects of indapamide?
Indapamide can cause electrolyte imbalances such as low potassium, low sodium, low magnesium, or high calcium, along with volume depletion and low blood pressure. It may also raise blood sugar (worsening or unmasking diabetes) and raise uric acid levels, which can trigger gout. Increased sun sensitivity and, rarely, serious skin reactions are also possible. Talk to your doctor about the full list of risks and whether they apply to you.
Does indapamide cause weight loss or dehydration?
Indapamide is a diuretic, so it causes your body to release extra fluid through urine, which can show up as a temporary drop on the scale — that's water loss, not fat loss. Because it removes fluid and sodium, indapamide can also cause dehydration or volume depletion, especially in older adults or when combined with other diuretics, so your doctor may monitor you for signs of this.
What is the best time of day to take indapamide?
Your doctor or the prescription label will give you specific instructions, and you should follow those exactly. Because indapamide increases urination, many people find it easier to take diuretics earlier in the day to avoid nighttime bathroom trips, but ask your doctor or pharmacist for guidance specific to your situation and any other medications you take.
How much does Indapamide cost without insurance?
The price of Indapamide without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 84% off retail prices with a free Rx.com coupon.
What are the common side effects of Indapamide?
Common side effects of Indapamide may include: Blurred vision or changes in vision, Change in how much or how often you urinate, Blistering, peeling, red skin rash, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Lightheadedness, dizziness, or fainting. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Indapamide?
Generic versions may be available for Indapamide. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Indapamide on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Indapamide?
The cheapest pharmacy for Indapamide depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Indapamide near you.

Indapamide Coupons & Prices

Indapamide 1.25MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Indapamide Tablet — prescription drug image
Prescription
Indapamide 1.25mg (15)
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Looking for an indapamide coupon? Indapamide is already sold only as a generic in the U.S. (its brand, Lozol, was discontinued), but the price at the counter still isn't fixed — it can vary widely from one pharmacy to the next for the exact same prescription. Rx.com compares prices at more than 60,000 pharmacies so you can see where indapamide costs less before you fill it; enter your ZIP above to see today's price near you.

What Is Indapamide and How Does It Work?

Indapamide is a thiazide-like diuretic, or "water pill," chemically classed as an indoline/sulfonamide derivative. It's FDA-approved to treat hypertension (high blood pressure), either alone or together with other blood pressure medicines, and to treat salt and fluid retention (edema) linked to congestive heart failure. It works by causing the kidneys to excrete extra sodium and water into the urine, which lowers blood pressure and reduces swelling.

Because indapamide is a sulfonamide derivative, tell your doctor if you have a sulfa allergy before starting it.

Indapamide Cost: Why Prices Vary and How to Compare

As a long-available generic, indapamide doesn't have a brand-name version driving up the price — but that doesn't mean every pharmacy charges the same amount. Cash prices for generic drugs can differ significantly by pharmacy, by location, and by which supplier a pharmacy stocks. That's why it pays to compare before you fill, rather than assuming your usual pharmacy has the best price.

Rx.com searches pricing across more than 60,000 U.S. pharmacies so you can find a lower price on the same prescription your doctor wrote. Enter your ZIP code above to see current pricing options near you — no manufacturer coupon exists for indapamide since the brand (Lozol) is discontinued, so comparing pharmacy cash prices is the main way to control your cost.

Indapamide vs. Other Blood Pressure Medicines

Indapamide is often compared to other diuretics and antihypertensives. It's frequently confused with hydrochlorothiazide, another commonly prescribed water pill — the two work similarly but are chemically distinct, and your doctor chooses between them (or chlorthalidone, a related thiazide-like diuretic) based on your individual health needs.

For blood pressure that needs more than one medicine, indapamide is sometimes combined with drugs from other classes, such as lisinopril (an ACE inhibitor) or amlodipine (a calcium channel blocker). For fluid retention from heart failure specifically, your doctor might instead consider a loop diuretic like furosemide, or a potassium-sparing option like spironolactone. Never switch between these medications without your doctor's guidance — they're not interchangeable.

Indapamide Safety Information

Indapamide doesn't carry an FDA boxed warning, but it does require some precautions. It can cause electrolyte imbalances — including low potassium, low sodium, low magnesium, or high calcium — as well as volume depletion and low blood pressure, particularly in older adults or when combined with other diuretics. Your doctor will likely check your kidney function, electrolytes, and blood pressure periodically while you're on it.

Indapamide may also worsen or unmask diabetes (blood sugar should be monitored) and can raise uric acid levels, which may trigger gout. It should be avoided in severe kidney or liver impairment, in anuria (inability to urinate), and during pregnancy or breastfeeding. Some people experience increased sun sensitivity, and rare but serious skin reactions are possible. This isn't a complete list of risks — talk to your doctor or pharmacist about whether indapamide is right for you.

Sources & accuracy

This Indapamide information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Indapamide on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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