Lo Loestrin Fe
Lo Loestrin Fe 28 Tablets
What is Lo Loestrin Fe?
Lo Loestrin Fe is a contraceptive used to prevent pregnancy. There is not a Lo Loestrin Fe generic drug currently available on the market. On average Lo Loestrin Fe is priced at about $149 for a supply of 28, 10 mcg-1 mg tablets. Luckily, you can use our Rx.com savings offer to receive an average Lo Loestrin Fe discount of up to 80% off the retail price at participating pharmacies near you.Side Effects
- Vision loss, double or blurred vision
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Breast lumps, tenderness, pain, swelling, or discharge
Warnings
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Although you are using this medicine to prevent pregnancy, you should know that using this medicine while you are pregnant could harm the unborn baby. Tell your doctor right away if you think you have become pregnant.
- Tell your doctor if you are breastfeeding, or if you had given birth within 4 weeks before you start using this medicine. Tell your doctor if you have kidney disease, diabetes, gallbladder disease, hereditary angioedema, high blood pressure, high cholesterol, migraines, or a history of cervical cancer, depression, or chloasma gravidarum (skin disorder during pregnancy). Tell your doctor if you smoke or if you are having a surgery that requires inactivity for a long time. Tell your doctor if you wear contact lenses.
- This medicine may cause the following problems:Increased risk of heart attack, stroke, or blood clotsIncreased risk of breast, endometrial, ovarian, or cervical cancerLiver problems (including liver tumor or cancer)High blood pressureGallbladder diseaseHigh cholesterol in the bloodEye or vision problems
Prescription savings · · · ·
What is Lo Loestrin Fe ?
Lo Loestrin Fe is a contraceptive used to prevent pregnancy. There is not a Lo Loestrin Fe generic drug currently available on the market. On average Lo Loestrin Fe is priced at about $149 for a supply of 28, 10 mcg-1 mg tablets. Luckily, you can use our Rx.com savings offer to receive an average Lo Loestrin Fe discount of up to 80% off the retail price at participating pharmacies near you.- Vision loss, double or blurred vision
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Breast lumps, tenderness, pain, swelling, or discharge
- Sudden and severe stomach pain, nausea, vomiting, lightheadedness
- Chest pain that may spread, trouble breathing, unusual sweating, fainting
- Numbness or weakness in your arm or leg, or on one side of your body, pain in your lower leg (calf), sudden or severe headache, or problems with vision, speech, or walking
- Dark urine or pale stools, loss of appetite, yellow skin or eyes
- Unusual, unexpected, or heavy vaginal bleeding
- Unusual moods or behavior, depression
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Although you are using this medicine to prevent pregnancy, you should know that using this medicine while you are pregnant could harm the unborn baby. Tell your doctor right away if you think you have become pregnant.
- Tell your doctor if you are breastfeeding, or if you had given birth within 4 weeks before you start using this medicine. Tell your doctor if you have kidney disease, diabetes, gallbladder disease, hereditary angioedema, high blood pressure, high cholesterol, migraines, or a history of cervical cancer, depression, or chloasma gravidarum (skin disorder during pregnancy). Tell your doctor if you smoke or if you are having a surgery that requires inactivity for a long time. Tell your doctor if you wear contact lenses.
- This medicine may cause the following problems:Increased risk of heart attack, stroke, or blood clotsIncreased risk of breast, endometrial, ovarian, or cervical cancerLiver problems (including liver tumor or cancer)High blood pressureGallbladder diseaseHigh cholesterol in the bloodEye or vision problems
- This medicine will not protect you from getting HIV/AIDS or other sexually transmitted infections.
- This medicine may cause skin discoloration. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.
- You might have some light bleeding or spotting, especially during the first 3 months of using this medicine. This is usually normal and should not last long. However, if you have heavy bleeding or the bleeding lasts more than a few days in a row, call your doctor.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
Lo Loestrin Fe Coupons & Prices
Lo Loestrin Fe 28 Tablets
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If you're searching for a Lo Loestrin Fe coupon, here's what matters first: Lo Loestrin Fe is a brand-name combination birth control pill with no substitutable generic currently available, so pharmacy price and coupon eligibility make a real difference — enter your ZIP above to see today's price at pharmacies near you, and compare that against the manufacturer's own savings card before you fill.
What is Lo Loestrin Fe and how does it work?
Lo Loestrin Fe is a combination oral contraceptive that combines norethindrone acetate and ethinyl estradiol tablets, ethinyl estradiol-only tablets, and non-hormonal ferrous fumarate (iron) tablets in a 28-day pack. It delivers the lowest dose of estrogen (10 mcg ethinyl estradiol) of any combined birth control pill on the U.S. market during its active-hormone taper phase. The brown iron tablets at the end of the pack contain no hormones and have no contraceptive or therapeutic effect — they're included only to help you keep the daily pill-taking habit through all 28 days.
Lo Loestrin Fe is FDA-approved for one purpose: preventing pregnancy in women who choose it as their method of contraception. It is not FDA-approved for acne, PCOS, or menstrual-cycle regulation, although combination pills in this class are sometimes prescribed off-label by providers for those reasons or for heavy menstrual bleeding — ask your provider whether that applies to you.
Manufacturer savings card vs. the Rx.com cash coupon
Lo Loestrin Fe's manufacturer offers an official savings card program (available directly at loloestrin.com) that can lower your out-of-pocket cost, but like most manufacturer copay cards it's generally limited to patients with commercial (private) insurance, and the exact terms, eligibility rules, and any dollar caps vary and can change — check the current terms on the manufacturer's site before assuming you qualify.
If you're uninsured, on Medicare or Medicaid, or your manufacturer card is declined at the counter, a Rx.com cash coupon is worth pulling up as a backup — it isn't tied to insurance status. Since there's no generic version of Lo Loestrin Fe on the market yet, comparing your coupon price across nearby pharmacies is the main lever you have for controlling cost. Enter your ZIP above to see today's price near you.
How Lo Loestrin Fe compares to other birth control pills
Lo Loestrin Fe isn't the only combination pill available, and it isn't right for everyone. Your provider may discuss it alongside other combined oral contraceptives, including Loestrin Fe (a higher-estrogen relative in the same product family), Junel Fe, and Yaz, or a different pill formulation such as Sprintec. If estrogen isn't appropriate for you — for example, due to a smoking history or clotting risk — a progestin-only option like norethindrone may come up as an alternative. Only your prescriber can say which option fits your health history; this page is not a substitute for that conversation.
Safety information
Lo Loestrin Fe carries a boxed warning: cigarette smoking increases the risk of serious cardiovascular side effects from combination oral contraceptives like this one. That risk rises with age and with heavier smoking (15 or more cigarettes a day), and it is markedly increased in women over 35 — women over 35 who smoke should not use Lo Loestrin Fe. The label also lists other serious risks, including blood clots (venous thromboembolism), stroke, and heart attack, particularly in women with additional risk factors such as high blood pressure, diabetes, obesity, migraine with aura, or a known clotting disorder. It's contraindicated in women with a history of blood clots, certain cancers, liver disease or liver tumors, uncontrolled high blood pressure, migraine with aura, or major surgery requiring extended immobility.
Common, less serious side effects include irregular or breakthrough bleeding (most common in the first few months), nausea, headache, and breast tenderness. A number of medications — including certain anticonvulsants, rifampin, St. John's wort, and some HIV or hepatitis C antiviral regimens — can reduce how well Lo Loestrin Fe prevents pregnancy, so tell your provider and pharmacist about everything else you take. This is general information, not medical advice; talk with your provider about whether Lo Loestrin Fe is safe for you.
This Lo Loestrin Fe information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Lo Loestrin Fe on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.