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Piroxicam Capsule — prescription drug image

Piroxicam

Piroxicam 10MG

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What is Piroxicam?

Feldene is a nonsteroidal anti-inflammatory drug that is prescribed to patients diagnosed with osteoarthritis and rheumatoid arthritis to relieve pain. Piroxicam is the generic version of Feldene. The average Feldene price is about $814 for a supply of 100, 10 mg oral capsules. You can use our Rx.com savings offer to get a Feldene discount of up to 80% off of the retail price at participating pharmacies near you.

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What is Piroxicam ?

Feldene is a nonsteroidal anti-inflammatory drug that is prescribed to patients diagnosed with osteoarthritis and rheumatoid arthritis to relieve pain. Piroxicam is the generic version of Feldene. The average Feldene price is about $814 for a supply of 100, 10 mg oral capsules. You can use our Rx.com savings offer to get a Feldene discount of up to 80% off of the retail price at participating pharmacies near you.
  • Chest pain that may spread, trouble breathing, coughing up blood, unusual sweating, fainting
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Unusual bleeding, bruising, or weakness
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash
  • Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
  • Change in how much or how often you urinate, painful or difficult urination
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Bloody or black, tarry stools, severe stomach pain, vomiting blood or material that looks like coffee grounds
  • Tell your doctor if you are pregnant. Do not use this medicine during the later part of a pregnancy, unless your doctor tells you to.
  • Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, asthma, bleeding problems, heart failure, high blood pressure, other heart or circulation problems, a recent heart attack, or a history of stomach or bowel problems (including bleeding or ulcers). Tell your doctor if you smoke or drink alcohol.
  • This medicine may cause the following problems:Increased risk of blot clots, heart attack, stroke, or heart failureStomach or bowel problems (including bleeding, ulcers, or perforation)Kidney problemsLiver problemsHigh blood pressureSerious skin reactions, including exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms (DRESS)Changes in vision
  • This medicine may cause a delay in ovulation for women and may affect their ability to have children. If you plan to have children, talk with your doctor before using this medicine.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Unusual bleeding, bruising, or weakness
What is piroxicam used for?
Piroxicam is FDA-approved for the relief of the signs and symptoms of osteoarthritis and rheumatoid arthritis. It is not typically used for short-term aches and pains the way over-the-counter NSAIDs are.
Is there a brand-name version of piroxicam?
The original brand, Feldene, is no longer marketed in the United States. Piroxicam is available only as a generic capsule (10 mg and 20 mg).
How long does it take for piroxicam to work?
Because piroxicam has a long half-life, steady blood levels aren't reached for about 7 to 12 days. Some relief may be felt earlier, but full benefit builds gradually over several weeks of consistent use.
Can I take piroxicam with other NSAIDs or aspirin?
You generally shouldn't combine piroxicam with other NSAIDs or regular aspirin use, as this increases the risk of stomach bleeding and other side effects without added benefit. Ask your doctor or pharmacist before combining pain relievers.
Who should not take piroxicam?
People with a known allergy to piroxicam or other NSAIDs, a history of asthma or allergic reactions triggered by aspirin/NSAIDs, or those needing pain relief around coronary artery bypass graft (CABG) surgery should not take it. It should be used cautiously in older adults and anyone with a history of stomach ulcers, heart disease, or kidney problems.
How much does Piroxicam cost without insurance?
The price of Piroxicam without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 60% off retail prices with a free Rx.com coupon.
What are the common side effects of Piroxicam?
Common side effects of Piroxicam may include: Chest pain that may spread, trouble breathing, coughing up blood, unusual sweating, fainting, Rapid weight gain, swelling in your hands, ankles, or feet, Unusual bleeding, bruising, or weakness, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Blistering, peeling, red skin rash. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Piroxicam?
Generic versions may be available for Piroxicam. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Piroxicam on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Piroxicam?
The cheapest pharmacy for Piroxicam depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Piroxicam near you.

Piroxicam Coupons & Prices

Piroxicam 10MG

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Piroxicam Capsule — prescription drug image
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Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve the pain, swelling, and stiffness of osteoarthritis and rheumatoid arthritis. It's sold only as a generic capsule today, and cash prices for it can vary quite a bit from one pharmacy to the next. If you're filling a piroxicam prescription, a Rx.com coupon can help you compare pharmacy prices in your area — enter your ZIP above to see today's price near you.

What Is Piroxicam and How Does It Work?

Piroxicam belongs to the oxicam class of NSAIDs. It works by blocking cyclooxygenase (COX) enzymes, which lowers production of prostaglandins — the body chemicals that drive inflammation, pain, and swelling in the joints. It comes as an oral capsule (10 mg and 20 mg) and is generally taken once daily. Because it has a long half-life, it can take one to two weeks of regular use before its full effect is felt.

How Much Does Piroxicam Cost, and How to Save

Piroxicam is available only as a generic — there's no brand-name version sold in the U.S. anymore — but that doesn't mean every pharmacy charges the same price. Generic drug prices can differ significantly by pharmacy and by location, so it pays to compare before you fill. Rx.com compares cash prices for piroxicam across more than 60,000 U.S. pharmacies so you can find a lower price and a free coupon to use at checkout, with or without insurance.

Piroxicam vs. Other NSAIDs

Piroxicam is one of several prescription NSAIDs used for arthritis pain, alongside options like meloxicam, naproxen, and diclofenac. Piroxicam's long half-life allows once-daily dosing, which some patients find more convenient, but it also means side effects can take longer to resolve after stopping it. Your prescriber can help decide which NSAID best fits your health history and other medications.

Piroxicam Safety Information

Like all NSAIDs, piroxicam carries an FDA boxed warning for an increased risk of serious cardiovascular thrombotic events (heart attack and stroke) and serious gastrointestinal events, including bleeding, ulceration, and perforation of the stomach or intestines, which can occur without warning and be fatal. It is contraindicated for pain right before or after coronary artery bypass graft (CABG) surgery, in people with a history of asthma or allergic-type reactions after taking aspirin or other NSAIDs, and in those with a prior serious skin reaction to an NSAID. Older adults are at higher risk for GI complications. This isn't a complete list of risks — talk with your doctor or pharmacist about whether piroxicam is right for you.

Sources & accuracy

This Piroxicam information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Piroxicam on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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