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Trandolapril Tablet — prescription drug image

Trandolapril

Trandolapril 4MG

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What is Trandolapril?

Trandolapril is a generic drug that is used to treat high blood pressure and certain other conditions. The average Trandolapril cash price is manageable at about $41 for a supply of 30, 4 mg tablets. You can further lower your Trandolapril cost by using our free savings card at a local pharmacy that participates with Rx.com. Using our Trandolapril coupon can help you save up to 80 percent off of the retail cost of your medication.

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What is Trandolapril ?

Trandolapril is a generic drug that is used to treat high blood pressure and certain other conditions. The average Trandolapril cash price is manageable at about $41 for a supply of 30, 4 mg tablets. You can further lower your Trandolapril cost by using our free savings card at a local pharmacy that participates with Rx.com. Using our Trandolapril coupon can help you save up to 80 percent off of the retail cost of your medication.
  • Blistering, peeling, red skin rash
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Severe stomach pain (with or without nausea or vomiting)
  • Confusion, weakness, uneven heartbeat, trouble breathing, numbness in your hands, feet, or lips
  • Lightheadedness, dizziness, fainting
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate
  • Fever, chills, sore throat, body aches
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, diabetes, heart failure, heart or blood vessel disease, or an autoimmune disorder (including lupus or scleroderma).
  • This medicine may cause the following problems:Angioedema (severe swelling), including head, neck, and intestinal swellingLow blood pressureLiver problemsKidney problems
  • This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Stand or sit up slowly if you feel lightheaded or dizzy.
  • Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in a normal range. You may have to take blood pressure medicine for the rest of your life.
  • Tell any doctor or dentist who treats you that you are using this medicine.
  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
What is trandolapril used for?
Trandolapril tablets are FDA-approved to treat high blood pressure, either alone or with other blood pressure medicines such as hydrochlorothiazide. They are also approved for use in stable patients who have evidence of left-ventricular systolic dysfunction, or who are symptomatic from congestive heart failure, within the first few days after an acute heart attack. The label describes that benefit in specific terms: giving trandolapril to Caucasian patients has been shown to decrease the risk of death (principally cardiovascular death) and to decrease the risk of heart failure-related hospitalization, and the label notes that the trial population behind this indication was entirely Caucasian. Any other use is off-label and is a decision for your prescriber.
What are the most common side effects of trandolapril?
In the label's placebo-controlled high blood pressure studies, the most frequently reported side effects were cough (about 1.9% of patients, versus 0.4% on placebo), dizziness (about 1.3% versus 0.4%), and diarrhea (about 1% versus 0.4%). The cough is a known effect of ACE inhibitors as a class and is one of the main reasons people ask to switch. Get emergency help for swelling of the face, lips, tongue, or throat, or trouble breathing, which can signal angioedema. Tell your doctor about dizziness or fainting, since trandolapril can lower blood pressure too much in some people, and keep any lab appointments, since it can raise potassium and affect kidney test results.
Is trandolapril the same as Mavik, and is Mavik still available?
Mavik was the brand name for trandolapril, and it has been discontinued in the United States. It is no longer marketed here. The generic trandolapril tablets that pharmacies fill today contain the same active ingredient. Trandolapril is also made in a combination tablet with extended-release verapamil that was sold under the brand name Tarka; Tarka has been discontinued in the United States as well, and that combination is dispensed as generic trandolapril and verapamil HCl extended-release tablets.
How is trandolapril different from lisinopril or ramipril?
All three are ACE inhibitors and lower blood pressure the same basic way, so their side effects and warnings are largely similar, including the dry cough and the boxed warning about use in pregnancy. They differ in dosing, in how the body processes and clears them, and in which conditions each one is specifically FDA-approved for. Which one is right for you depends on your other conditions and how you respond, so ask your prescriber rather than switching on your own.
Can you take trandolapril while pregnant?
No. Trandolapril has a boxed warning for fetal toxicity. Drugs that act on the renin-angiotensin system can cause injury and death to a developing baby. If you find out you are pregnant while taking trandolapril, contact your doctor immediately, as the label directs that the medicine be stopped as soon as pregnancy is detected. If you are pregnant, planning a pregnancy, or could become pregnant, tell your prescriber so a safer blood pressure option can be chosen.
How much does Trandolapril cost without insurance?
The price of Trandolapril without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Trandolapril?
Common side effects of Trandolapril may include: Blistering, peeling, red skin rash, Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes, Severe stomach pain (with or without nausea or vomiting), Confusion, weakness, uneven heartbeat, trouble breathing, numbness in your hands, feet, or lips, Lightheadedness, dizziness, fainting. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Trandolapril?
Generic versions may be available for Trandolapril. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Trandolapril on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Trandolapril?
The cheapest pharmacy for Trandolapril depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Trandolapril near you.

Trandolapril Coupons & Prices

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Use a free trandolapril coupon from Rx.com to see what this blood-pressure tablet actually costs at pharmacies near you. Trandolapril is a generic ACE inhibitor used to treat high blood pressure and to protect the heart after a heart attack in people with weakened heart function. Cash prices for the same prescription can differ quite a bit from one pharmacy to the next, even across the street, so it pays to compare before you fill. Rx.com checks prices at more than 60,000 pharmacies nationwide. Enter your ZIP code above to see today's price and print, text, or show your coupon at the counter.

What is trandolapril and how does it work?

Trandolapril is an angiotensin-converting enzyme (ACE) inhibitor. ACE inhibitors block an enzyme your body uses to make a substance that tightens blood vessels. With less of that substance around, blood vessels relax and widen, blood pressure comes down, and the heart does not have to work as hard to pump.

The FDA has approved trandolapril tablets for two uses. The first is high blood pressure (hypertension), either on its own or together with other blood pressure medicines such as hydrochlorothiazide. The second is heart failure after a heart attack: trandolapril is indicated in stable patients who have evidence of left-ventricular systolic dysfunction, or who are symptomatic from congestive heart failure, within the first few days after an acute heart attack. It is worth knowing exactly how the label frames the benefit: it states that giving trandolapril to Caucasian patients has been shown to decrease the risk of death (principally cardiovascular death) and to decrease the risk of heart failure-related hospitalization, and it notes that the population in the trial behind this indication (TRACE) was entirely Caucasian. Doctors sometimes prescribe ACE inhibitors for other heart and kidney conditions, but those uses are not part of trandolapril's FDA labeling, and your prescriber is the right person to explain why a particular medicine was chosen for you.

What trandolapril costs without insurance, and how to pay less

Trandolapril is available as an FDA-approved generic, so you should not need a brand-name product to fill this prescription. There is no manufacturer savings card for trandolapril. That makes a cash discount coupon the main way to bring the price down if you are uninsured, have a high deductible, or your plan does not cover this drug well.

The important thing to know is that pharmacies set their own cash prices, and the spread between the cheapest and the most expensive pharmacy in the same town can be surprising. A price at one chain tells you nothing about the price a mile away. That is why comparing matters more than any single number. Enter your ZIP above to see today's trandolapril price at pharmacies near you, then bring the coupon to the counter and ask the pharmacist to run it as a cash discount instead of your insurance if it comes out lower. Filling a 90-day supply instead of 30 days is also worth asking your prescriber about, since it can cut the number of trips and fills you pay for.

Trandolapril vs. other ACE inhibitors and alternatives

Trandolapril was sold under the brand name Mavik, which has been discontinued in the United States; the generic tablets are what pharmacies dispense today. Trandolapril is also made in a combination tablet with extended-release verapamil, which was sold under the brand name Tarka. Tarka has also been discontinued in the United States, so that combination is dispensed as a generic today: trandolapril and verapamil HCl ER.

All ACE inhibitors work the same basic way, but they differ in how often they are taken, how they are cleared from the body, and what they are FDA-approved for. Common alternatives your prescriber may consider include lisinopril, ramipril, enalapril, benazepril, quinapril, and fosinopril. If an ACE inhibitor causes a persistent dry cough, doctors often switch patients to an ARB such as losartan, which lowers blood pressure through a related pathway but rarely causes that cough. Never switch or stop a blood pressure medicine on your own; talk with your prescriber first, and compare prices on whichever drug you land on, since generic prices vary pharmacy to pharmacy.

Safety information you should know

Trandolapril carries a boxed warning for fetal toxicity. Medicines that act on the renin-angiotensin system can injure or kill a developing baby. If you become pregnant while taking trandolapril, stop the medicine and tell your doctor right away. Trandolapril should not be used by anyone who has had an allergic reaction to it, who has had angioedema (deep swelling) with any ACE inhibitor, or who has hereditary or idiopathic angioedema. It should not be combined with aliskiren in people with diabetes, and it must not be taken within 36 hours of switching to or from sacubitril/valsartan (Entresto).

Call for emergency help if you develop swelling of the face, lips, tongue, or throat, or trouble breathing or swallowing. This kind of angioedema is rare but can be life-threatening, and it occurs more often in Black patients; swelling of the intestines can also happen and may show up as belly pain. Other risks include low blood pressure with dizziness or fainting (especially if you are dehydrated, on a diuretic, or have heart failure), rises in kidney blood tests, high potassium (more likely with kidney problems, diabetes, potassium supplements, potassium-sparing diuretics, or salt substitutes), low white blood cell counts, and rare liver problems including jaundice. Avoid taking an ACE inhibitor together with an ARB or aliskiren, and know that NSAID pain relievers can blunt the blood pressure benefit and stress the kidneys. This page is general information, not medical advice. Read the label that comes with your prescription and talk with your doctor or pharmacist about your own situation.

Sources & accuracy

This Trandolapril information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Trandolapril on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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