Clopidogrel Bisulfate Coupons & Prices

Looking for a clopidogrel bisulfate coupon? Clopidogrel bisulfate is the generic form of Plavix, a widely prescribed antiplatelet medicine that helps prevent blood clots in people at risk of heart attack and stroke. Because it is available as an FDA-approved generic, clopidogrel is usually already low-cost, but the cash price can still vary a lot from one pharmacy to the next. Rx.com compares clopidogrel prices across more than 60,000 U.S. pharmacies, so you can enter your ZIP above to see today's price near you and bring a free discount coupon to the counter.

What is clopidogrel bisulfate and how does it work?

Clopidogrel bisulfate is a P2Y12 platelet inhibitor (a thienopyridine antiplatelet agent). It works by keeping platelets in your blood from clumping together, which lowers the chance of a dangerous clot forming inside a narrowed or stented artery. It is the same active ingredient sold under the brand name Plavix.

Doctors prescribe clopidogrel to reduce the risk of heart attack, stroke, and cardiovascular death. It is FDA-approved for acute coronary syndrome (including unstable angina, NSTEMI, and STEMI), for people who have recently had a heart attack or a stroke, and for established peripheral arterial disease. It is also commonly used together with aspirin as dual antiplatelet therapy after a coronary stent is placed, to help prevent the stent from clotting off.

How much does clopidogrel cost without insurance?

Clopidogrel is available as a substitutable generic, so it is generally one of the more affordable antiplatelet options and is far less expensive than brand-name Plavix. Even so, the cash price you would pay without insurance is not the same everywhere, because different pharmacies set different prices for the exact same tablets. That is why comparing pharmacies before you fill matters.

Rx.com checks clopidogrel pricing across more than 60,000 pharmacies so you can find a lower cash price near you. Enter your ZIP above to see today's price and print or text yourself a free discount coupon. The coupon can be used whether or not you have insurance, and it is often worth comparing against your plan's copay.

Clopidogrel vs. other antiplatelet options

Clopidogrel is one of several medicines in the antiplatelet family, and the right choice depends on your specific heart condition and your doctor's judgment. Common alternatives include:

• Plavix — the brand-name version of the same clopidogrel molecule.
• Ticagrelor (Brilinta) — another P2Y12 inhibitor often used after acute coronary syndrome.
• Prasugrel (Effient) — a P2Y12 inhibitor sometimes used after stenting.
• Aspirin, or the combination aspirin-dipyridamole, which work through different mechanisms and are sometimes used alone or with clopidogrel.

Only your prescriber can decide which antiplatelet is best for you. If you have been prescribed clopidogrel specifically, do not switch on your own, and use Rx.com to compare the price of the exact drug you were prescribed.

Safety, warnings, and interactions

Clopidogrel carries an FDA boxed warning about how the body activates the drug. Clopidogrel must be converted to its active form by a liver enzyme called CYP2C19. People who are CYP2C19 "poor metabolizers" get a reduced antiplatelet effect and may have worse cardiovascular outcomes at standard doses. Genotype testing is available, and doctors may consider a different P2Y12 inhibitor for these patients. For this reason, you should avoid strong CYP2C19 inhibitors such as omeprazole and esomeprazole while taking clopidogrel, because they can blunt its effect.

The main risk with clopidogrel is bleeding, which can be serious or even fatal, so it is contraindicated in anyone with active pathological bleeding. Do not stop the medicine on your own; stopping early raises the risk of clots, including stent thrombosis. A rare blood disorder called thrombotic thrombocytopenic purpura (TTP) has also been reported. This is general information, not medical advice, so talk with your doctor or pharmacist about your bleeding risk and all the medicines you take.