Clotrimazole-Betamethasone
Clotrimazole-Betamethasone 45GM of 1-0.05%
What is Clotrimazole-Betamethasone?
Clotrimazole-Betamethasone is an antifungal steroid that treats infections caused by fungus. The average price of Clotrimazole-Betamethasone is around $22 for a supply of 15 g, 1% topical cream. Use our Rx.com savings offer to get great discounts on Clotrimazole-Betamethasone at participating pharmacies near you.Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blurred vision or other changes in vision, eye pain
- Severe itching, burning, or skin irritation
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have liver problems, diabetes, eye problems (including cataracts or glaucoma), or a skin infection.
- Do not use this medicine on anyone younger than 17 years of age.
- This medicine may cause the following problems:Adrenal gland problems, including Cushing syndromeHigh blood sugarEye or vision problems (including cataracts, glaucoma)
- Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
- If your symptoms do not improve after 1 or 2 weeks of treatment, or if they get worse, check with your doctor.
Prescription savings · · · ·
What is Clotrimazole-Betamethasone ?
Clotrimazole-Betamethasone is an antifungal steroid that treats infections caused by fungus. The average price of Clotrimazole-Betamethasone is around $22 for a supply of 15 g, 1% topical cream. Use our Rx.com savings offer to get great discounts on Clotrimazole-Betamethasone at participating pharmacies near you.- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blurred vision or other changes in vision, eye pain
- Severe itching, burning, or skin irritation
- Round, puffy face
- Weight gain around your neck, upper back, breast, face, or waist
- Color changes on the skin, dark freckles, easy bruising, muscle weakness
- Tell your doctor if you are pregnant or breastfeeding, or if you have liver problems, diabetes, eye problems (including cataracts or glaucoma), or a skin infection.
- Do not use this medicine on anyone younger than 17 years of age.
- This medicine may cause the following problems:Adrenal gland problems, including Cushing syndromeHigh blood sugarEye or vision problems (including cataracts, glaucoma)
- Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
- If your symptoms do not improve after 1 or 2 weeks of treatment, or if they get worse, check with your doctor.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Clotrimazole-Betamethasone Coupons & Prices
Clotrimazole-Betamethasone 45GM of 1-0.05%
Clotrimazole-Betamethasone prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 15gm of 1-0.05% · Tube Of Cream | 45 | $38.10 | $17.99 |
| 45gm of 1-0.05% · Tube Of Cream | 45 | $89.85 | $17.99 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
If you're comparing clotrimazole-betamethasone coupon prices, it helps to know what you're actually pricing: this is a combination cream (or lotion) that pairs an antifungal with a corticosteroid, sold under the brand name Lotrisone as well as in generic form, and pharmacy cash prices for it can vary widely from one store to the next — so it's worth checking before you fill. Rx.com compares pricing across 60,000+ U.S. pharmacies so you can see where it costs less near you; enter your ZIP above to see today's price.
What is clotrimazole-betamethasone, and how does it work?
Clotrimazole and betamethasone dipropionate cream (brand name Lotrisone) combines two medicines in one product: clotrimazole, an antifungal that stops the growth of the fungi that cause ringworm-type skin infections, and betamethasone dipropionate, a corticosteroid that calms the itching, redness, and inflammation those infections cause. It's FDA-approved for symptomatic inflammatory tinea pedis (athlete's foot), tinea cruris (jock itch), and tinea corporis (ringworm) in patients 17 and older. It is not approved for tinea versicolor, vaginal yeast infections, or oral thrush — plain clotrimazole (without the steroid) is used for those instead.
Cost and coupon savings: why prices vary so much
A generic version of clotrimazole-betamethasone cream is available, so you're not limited to paying brand-name Lotrisone pricing. That said, cash prices for the same generic tube can differ noticeably from one pharmacy to the next depending on where you fill it — there isn't one standard price nationwide. Rather than assume any single pharmacy is cheapest, it's worth comparing before you fill, especially if you're paying without insurance.
- Enter your ZIP above to compare pharmacy prices near you
- Ask your pharmacist whether the generic is in stock — it's the same medicine as Lotrisone
- Because this combination is meant for short-term use, most people only need one tube per course of treatment
Clotrimazole-betamethasone vs. plain clotrimazole and other options
Clotrimazole-betamethasone is meant for short-term use — typically up to about two weeks for jock itch or ringworm, and up to about four weeks for athlete's foot — while the inflammation and itching are at their worst. Once symptoms calm down, many prescribers switch patients to plain clotrimazole alone (without the added steroid) to finish clearing the fungal infection, since long-term steroid use on the skin carries its own risks. Other antifungals sometimes used for these same tinea infections include terbinafine and ketoconazole. If your prescriber wants an antifungal-steroid combination for a different diagnosis, nystatin-triamcinolone is another combination product to ask about; a low-potency steroid like hydrocortisone or the steroid component alone, betamethasone dipropionate, may come up in that conversation too. Your pharmacist or provider can say which fits your specific infection.
Safety information
Clotrimazole-betamethasone cream does not carry an FDA boxed warning, but the label does have some important guardrails. It's for skin use only — not for the eyes, mouth, or inside the vagina — and it isn't recommended for diaper rash or for patients under 17, since children absorb topical steroids more readily and face a higher risk of adrenal suppression. With any topical steroid, using it over a large area of skin, for longer than directed, or under a bandage or other occlusive covering (unless your provider specifically tells you to) can increase how much steroid the body absorbs, which in rare cases can affect adrenal function, blood sugar, or — in children — growth. Stop and call your provider if the treated area gets more irritated, or if the infection seems to be getting worse instead of better. This is general information, not medical advice — talk with your provider or pharmacist about how it applies to you.
This Clotrimazole-Betamethasone information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Clotrimazole-Betamethasone on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.