Codeine Sulfate Coupons & Prices

Looking for a codeine sulfate coupon? Codeine sulfate is only available as a generic (there is no current branded single-entity product), but that does not mean every pharmacy charges the same amount — cash prices for this opioid pain medication can vary widely from one pharmacy to the next. Rx.com compares pricing across 60,000+ pharmacies so you can see how your local options stack up before you fill; enter your ZIP above to see today's price.

What Is Codeine Sulfate?

Codeine sulfate is an opioid agonist analgesic approved by the FDA for the management of mild to moderate pain in adults, in situations where an opioid is appropriate and other treatment options are not adequate. It's dosed as needed, typically every 4 hours, up to a maximum set by your prescriber. Codeine sulfate was historically combined with acetaminophen in products marketed as Tylenol with Codeine, but the single-ingredient (single-entity) codeine sulfate tablets and oral solution covered on this page are labeled specifically for pain, not for cough.

Codeine Sulfate Cost Without Insurance

Because codeine sulfate is generic-only, there's no manufacturer savings card to check — but that also means pharmacies price it independently, and cash prices can differ a lot by location and by pharmacy chain. As a Schedule II controlled substance, not every pharmacy stocks it in the same quantities, which is another reason prices and availability are worth comparing before you go. Rather than guessing, enter your ZIP code above and Rx.com will show you how nearby pharmacies compare, so you can choose the one that works best for your prescription.

Codeine Sulfate vs. Other Opioid Pain Medications

Codeine sulfate is one of several opioid options a prescriber may consider for pain that doesn't respond well to non-opioid treatment. Depending on the type and severity of pain, a provider might instead consider tramadol, hydrocodone/acetaminophen, oxycodone, or morphine sulfate, or a combination product like acetaminophen with codeine. Every opioid carries its own dosing, interaction, and safety profile, so switching between them is a decision for you and your prescriber, not something to do on your own.

Codeine Sulfate Safety Information

Codeine sulfate carries FDA boxed warnings for the risk of addiction, abuse, and misuse even when taken as prescribed; life-threatening respiratory depression, which is highest when starting the medication or increasing the dose; the danger of accidental ingestion by children; and neonatal opioid withdrawal syndrome if used for a prolonged period during pregnancy. Taking codeine sulfate together with benzodiazepines or other central nervous system depressants can increase the risk of severe or fatal respiratory depression. It is contraindicated in children under 12 and in patients under 18 who have had a tonsillectomy or adenoidectomy, and it is not for use in significant respiratory depression, acute or severe asthma, known or suspected bowel obstruction, or in nursing mothers. These particular restrictions exist because some people are genetically "ultra-rapid metabolizers" who convert codeine to morphine in the body faster and more extensively than usual; in those individuals, even a normal dose of codeine can raise morphine levels to a life-threatening or fatal degree, which is the specific concern behind the pediatric and breastfeeding restrictions. Codeine sulfate is subject to an FDA-required Risk Evaluation and Mitigation Strategy (REMS) for opioid analgesics. This is general information, not medical advice — talk with your prescriber or pharmacist about whether codeine sulfate is right for you.