Cresemba
Cresemba 186MG
What is Cresemba?
Cresemba (isavuconazonium sulfate) is an antifungal medication used to treat invasive aspergillosis and mucormycosis, serious infections caused by certain types of fungi. This drug works by inhibiting the growth of fungi, thereby reducing the spread of infection, and is typically reserved for use in adults with compromised immune systems or conditions that make them more susceptible to these infections.Side Effects
- Lightheadedness, dizziness, fainting
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Warnings
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use effective birth control during treatment and for at least 28 days after the last dose.
- Tell your doctor if you are breastfeeding, or if you have liver disease or heart rhythm problems (including familial short QT syndrome). Tell your doctor if you had an allergic reaction to similar medicines (including itraconazole, ketoconazole, voriconazole).
- This medicine may cause the following problems:Liver problemsInfusion-related reactionsSerious skin reactions, including Stevens-Johnson syndrome
- This medicine may cause liver problems.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Prescription savings · · · ·
What is Cresemba ?
Cresemba (isavuconazonium sulfate) is an antifungal medication used to treat invasive aspergillosis and mucormycosis, serious infections caused by certain types of fungi. This drug works by inhibiting the growth of fungi, thereby reducing the spread of infection, and is typically reserved for use in adults with compromised immune systems or conditions that make them more susceptible to these infections.- Lightheadedness, dizziness, fainting
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
- Chills, dizziness, trouble breathing
- Dry mouth, increased thirst, muscle cramps, uneven heartbeat
- Decrease in how much or how often you urinate, difficult or painful urination
- Numbness or tingling, change in sense of touch
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use effective birth control during treatment and for at least 28 days after the last dose.
- Tell your doctor if you are breastfeeding, or if you have liver disease or heart rhythm problems (including familial short QT syndrome). Tell your doctor if you had an allergic reaction to similar medicines (including itraconazole, ketoconazole, voriconazole).
- This medicine may cause the following problems:Liver problemsInfusion-related reactionsSerious skin reactions, including Stevens-Johnson syndrome
- This medicine may cause liver problems.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Dry mouth, increased thirst, muscle cramps, uneven heartbeat
- Lightheadedness, dizziness, or fainting
- Numbness or tingling, change in sense of touch
Cresemba Coupons & Prices
Cresemba 186MG
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Looking for a Cresemba coupon? Cresemba (isavuconazonium sulfate) is a brand-name triazole antifungal used to treat serious, invasive fungal infections, and because there is no generic version, the price can be high. On this page you can enter your ZIP code above to see today's cash price at pharmacies near you and use the Rx.com discount coupon, which can help whether you are uninsured, on Medicare, or paying out of pocket. Below we explain what Cresemba is, how the manufacturer savings card compares with an Rx.com cash coupon, and how it stacks up against related antifungal medicines.
What is Cresemba and how does it work?
Cresemba is the brand name for isavuconazonium sulfate, a prodrug that the body converts into isavuconazole, an azole (triazole) antifungal. It is FDA-approved to treat invasive aspergillosis and invasive mucormycosis in adults 18 years and older. These are serious fungal infections that most often affect people with weakened immune systems. Cresemba comes as oral capsules and as an intravenous (IV) injection given in a healthcare setting.
Azole antifungals like isavuconazole work by blocking the fungus from making ergosterol, a key building block of its cell membrane, which stops the fungus from growing. Doctors sometimes also use Cresemba off-label to help prevent or treat other invasive fungal infections in immunocompromised patients, such as those with blood cancers or who have had a transplant. Any use should be directed and monitored by your prescriber.
Cresemba cost: manufacturer savings card vs. Rx.com cash coupon
There is no generic version of Cresemba available yet, so the brand-name price is what you will typically see. Astellas, the maker of Cresemba, offers a manufacturer savings card through its official site at activatethecard.com/cresemba. Manufacturer copay cards like this are generally limited to people with commercial (private) insurance and cannot be used if you have Medicare, Medicaid, or other government coverage. Terms, eligibility, and any savings limits are set by the manufacturer and can change, so check the official page for current details.
If you are uninsured, covered by Medicare, or the manufacturer card is declined at the pharmacy, an Rx.com cash coupon is a helpful alternative. It is a discount coupon that anyone can use instead of insurance. To compare, enter your ZIP above to see today's cash price with the Rx.com coupon at pharmacies near you. Astellas also runs patient support programs; you can learn about access and assistance options through the manufacturer's access and support resources.
Cresemba alternatives and related antifungals
Cresemba is one of several azole antifungals used for invasive fungal infections. The best choice depends on the specific infection, other medicines you take, and your prescriber's judgment. Related medicines you may see or want to price-compare include:
- voriconazole and its brand Vfend
- posaconazole and its brand Noxafil
- itraconazole
- fluconazole
Several of these are available as generics, which is often the biggest lever for lowering cost. Do not switch antifungals on your own, as they differ in what infections they treat and how they interact with other drugs. Talk with your provider about the right option for you.
Cresemba safety and side effects
Cresemba does not carry a boxed warning, but there are important safety points to know. It can affect the liver, so your provider may check your liver function, and it is used with caution in people with liver problems. It can cause harm to an unborn baby, so it should be avoided in pregnancy and effective contraception is advised. It should not be used by people with a known hypersensitivity to azole antifungals, and infusion-related reactions can occur with the IV form. Cresemba has important drug interactions through a liver enzyme called CYP3A4 and should not be combined with strong CYP3A4 inhibitors (such as ketoconazole) or strong inducers (such as rifampin, carbamazepine, or St. John's wort). It is also contraindicated in people with familial short QT syndrome.
Common side effects include nausea, vomiting, diarrhea, headache, elevated liver tests, low potassium (hypokalemia), constipation, and swelling in the arms or legs (peripheral edema). This is not a complete list and is not medical advice. Tell your provider about all medicines you take and any reactions you notice, and follow their guidance.
This Cresemba information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Cresemba on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.