Entyvio Coupons & Prices

Looking for an Entyvio coupon? Entyvio (vedolizumab) is a brand-name, gut-selective biologic used to treat moderately to severely active ulcerative colitis and Crohn's disease in adults, and it can be expensive because there is no generic or biosimilar version on the U.S. market yet. If you are uninsured, on Medicare, or your manufacturer copay card was declined, the free Rx.com cash coupon may lower what you pay at the pharmacy or specialty-pharmacy counter. Enter your ZIP above to see today's price at pharmacies near you.

What is Entyvio and how does it work?

Entyvio is the brand name for vedolizumab, an integrin receptor antagonist. It is a gut-selective biologic (a monoclonal antibody) that works by blocking the alpha4beta7 integrin, which reduces the inflammation that drives inflammatory bowel disease. Because it targets the gut, it is designed to calm intestinal inflammation with less effect on the rest of the immune system.

The FDA has approved Entyvio for adults with moderately to severely active ulcerative colitis (UC) and moderately to severely active Crohn's disease. It is used to induce and maintain clinical response and remission, to help achieve corticosteroid-free remission, and to improve the endoscopic appearance of the lining of the intestine in UC. It is given as an intravenous (IV) infusion for induction, and a subcutaneous (under-the-skin) injection is available for maintenance after IV induction.

Entyvio manufacturer savings card vs. the Rx.com cash coupon

Because there is no generic or biosimilar for Entyvio, cost is a real concern. The manufacturer, Takeda, runs an official copay support program (EntyvioConnect) advertised on the manufacturer's website, entyvio.com. Like most drugmaker copay cards, it is generally limited to people with commercial (private) insurance and is not available to patients covered by Medicare, Medicaid, or other government programs; the exact terms and eligibility can vary and change over time, so check the program's current rules. Takeda also offers patient-assistance resources through EntyvioConnect for eligible patients who qualify based on need.

The Rx.com cash coupon is different: it is a free discount you can use whether or not you have insurance. It is often most useful if you are uninsured, if you have Medicare and can't use a manufacturer copay card, or if the manufacturer card is declined at the counter. You can't combine a cash coupon with insurance on the same fill, so use whichever brings your out-of-pocket cost lower. Enter your ZIP above to see today's Rx.com price.

Entyvio alternatives and related biologics

Entyvio is one of several biologic options for ulcerative colitis and Crohn's disease. Which one is right depends on your diagnosis, prior treatments, and your gastroenterologist's judgment. Do not switch or stop a biologic on your own. Commonly discussed alternatives include:

• Humira (adalimumab), a TNF-blocker biologic
• Remicade (infliximab), an infused TNF-blocker
• Stelara (ustekinumab), an IL-12/23 blocker
• Skyrizi (risankizumab), an IL-23 blocker
• Rinvoq (upadacitinib), an oral JAK inhibitor

Some of these have their own manufacturer savings programs, and a few now have biosimilars that can lower cost. If price is a barrier with Entyvio, ask your prescriber whether another approved option fits your situation, and check the Rx.com price on any medicine you are prescribed.

Entyvio safety and side effects

This is general information, not medical advice; talk with your provider about your own risks. Entyvio does not carry a boxed warning, but it does have serious risks to be aware of. These include hypersensitivity and infusion-related reactions (including, rarely, anaphylaxis); an increased risk of serious and opportunistic infections; and a rare but potentially fatal brain infection called progressive multifocal leukoencephalopathy (PML), caused by the JC virus, so report any new neurologic symptoms right away. Liver injury has also been reported, and there is a theoretical risk of malignancy. Before starting, your provider should screen for tuberculosis and hepatitis B, and live vaccines should generally be avoided during treatment.

The most common side effects include common cold symptoms (nasopharyngitis), headache, joint pain, nausea, fever, fatigue, and upper respiratory infections. Contact your provider promptly about signs of infection, an allergic reaction, or any new or worsening neurologic changes.