Erythromycin Base
Erythromycin Base 500MG
What is Erythromycin Base?
Erythromycin-base is an antibiotic used to treat various bacterial infections, including skin and respiratory conditions. It works by stopping the growth of bacteria. Users can manage prescriptions online, find cost-saving coupons, and explore mail-order refill options on Rx.com.Side Effects
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Sudden and severe stomach pain.
- Nausea, vomiting, loss of appetite, or pain in your upper stomach.
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart rhythm problems (including QT prolongation), myasthenia gravis (severe muscle weakness), or stomach problems.
- This medicine may cause the following problems:Liver problemsHeart rhythm problemsSerious stomach problem, including infantile hypertrophic pyloric stenosis
- This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
- Muscle pain, tenderness, or weakness.
- Nausea, vomiting, loss of appetite, or pain in your upper stomach.
Prescription savings · · · ·
What is Erythromycin Base ?
Erythromycin-base is an antibiotic used to treat various bacterial infections, including skin and respiratory conditions. It works by stopping the growth of bacteria. Users can manage prescriptions online, find cost-saving coupons, and explore mail-order refill options on Rx.com.- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Sudden and severe stomach pain.
- Nausea, vomiting, loss of appetite, or pain in your upper stomach.
- Yellowing of your skin or the whites of your eyes.
- Muscle pain, tenderness, or weakness.
- Severe vomiting, irritability (in children).
- Muscle pain, tenderness, or weakness
- Severe diarrhea, stomach cramps, fever
- Swelling of the face, throat, or lips.
- Fast, slow, pounding, or uneven heartbeat
- Severe diarrhea (watery and may be bloody).
- Lightheadedness, dizziness, or fainting.
- Bloody or cloudy urine, decrease in how much or how often you urinate
- Hearing loss
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart rhythm problems (including QT prolongation), myasthenia gravis (severe muscle weakness), or stomach problems.
- This medicine may cause the following problems:Liver problemsHeart rhythm problemsSerious stomach problem, including infantile hypertrophic pyloric stenosis
- This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
- Muscle pain, tenderness, or weakness.
- Nausea, vomiting, loss of appetite, or pain in your upper stomach.
- Severe diarrhea (watery and may be bloody).
- Severe vomiting, irritability (in children).
- Sudden and severe stomach pain.
- Swelling of the face, throat, or lips.
- Yellowing of your skin or the whites of your eyes.
- Do not take this medicine for any other infection. This medicine will not work for colds, flu, or other viral infections.
- Call your doctor if your symptoms do not improve or if they get worse.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Do not take this medicine for any other infection. This medicine will not work for colds, flu, or other viral infections.
Erythromycin Base Coupons & Prices
Erythromycin Base 500MG
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If you're comparing erythromycin base coupon prices, it helps to know this generic antibiotic is usually inexpensive to begin with — but the price you're quoted can still vary widely from one pharmacy to the next. Rx.com compares pricing across more than 60,000 pharmacies so you can see how your local options stack up before you fill; enter your ZIP above to see today's price near you.
What Is Erythromycin Base and How Does It Work?
Erythromycin base is a macrolide antibiotic sold under brand names including Ery-Tab and PCE (PCE Dispertab); an older brand, Eryc, is no longer marketed in the United States. Macrolide antibiotics like erythromycin work by interfering with a bacterium's ability to make the proteins it needs to grow and multiply, which helps stop the infection from spreading while your body's immune system clears it.
Oral erythromycin base is FDA-labeled to treat a range of bacterial infections, including upper and lower respiratory tract infections, skin and skin-structure infections, pertussis (whooping cough), diphtheria (as an adjunct treatment), intestinal amebiasis, listeriosis, nongonococcal urethritis, and Chlamydia trachomatis infections, including in pregnant patients and newborns. Some prescribers also use low-dose erythromycin off-label to help stimulate stomach emptying (gastroparesis); this is a separate, off-label use and not the drug's primary purpose.
Erythromycin Base Cost: Why Comparing Pharmacies Still Matters
Erythromycin base is available as a generic. That doesn't mean every pharmacy charges the same amount, though — cash prices for the same medication and quantity can differ significantly depending on where you fill it, even within the same city. Because there's no manufacturer savings card for this generic, comparing pharmacy prices directly is the main way to find the best deal.
Rx.com pulls pricing from over 60,000 pharmacies nationwide so you can see how prices compare before you head to the counter. Enter your ZIP code above to check today's price at pharmacies near you.
Erythromycin Base vs. Other Antibiotics
Erythromycin base is one of several erythromycin-based products — erythromycin ethylsuccinate is a different salt form of the same antibiotic, often used when a liquid formulation is preferred. Other macrolide antibiotics that treat similar types of infections include azithromycin and clarithromycin, both of which are also available as generics.
Depending on the specific infection, a doctor may also consider a different class of antibiotic entirely, such as amoxicillin or doxycycline. Which option is right for you depends on the infection being treated, allergy history, and other medications you're taking — your prescriber will choose based on your specific situation.
Erythromycin Base Safety Information
Erythromycin base does not carry an FDA boxed warning, but it does have some important safety considerations. It can prolong the QT interval of the heart's electrical rhythm, and in rare cases this has been linked to a serious irregular heartbeat. Because of this, it should not be combined with certain medications, including terfenadine, astemizole, cisapride, pimozide, or ergotamine/dihydroergotamine, and it should be used with caution in people with existing QT prolongation, uncorrected low potassium or magnesium levels, significant bradycardia, or those taking other heart-rhythm medications. It should also not be combined with the statins lovastatin or simvastatin, due to an increased risk of a serious muscle condition.
Other reported issues include liver problems (cholestatic hepatitis), common gastrointestinal upset, and increased colchicine toxicity when the two are taken together. This is general safety information, not a complete list — tell your provider and pharmacist about every medication and supplement you take, and talk to them about whether erythromycin base is right for you.
This Erythromycin Base information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Erythromycin Base on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.