Est Estrogens-Methyltest Coupons & Prices

Looking for an esterified estrogens and methyltestosterone coupon? This combination hormone medicine (sold historically under the brand name Estratest) pairs esterified estrogens with the androgen methyltestosterone, and pricing for it varies a lot depending on which pharmacy fills it and which manufacturer's product they stock — enter your ZIP above to see today's price and compare over 60,000 pharmacies near you.

What is esterified estrogens and methyltestosterone, and how does it work?

Esterified estrogens and methyltestosterone is a combination hormone therapy that pairs an esterified (conjugated) estrogen mixture with methyltestosterone, a synthetic androgen. It was historically marketed under the brand name Estratest (including a half-strength version, Estratest H.S., and a full-strength version, Estratest F.S.). The estrogen component addresses menopausal hot flashes, while the added androgen is intended for women whose vasomotor symptoms aren't adequately relieved by estrogen alone and are thought to involve associated androgen deficiency.

This combination is a second-line option today — estrogen-alone or estrogen-plus-progestin regimens are generally tried first, and combination estrogen/androgen products are used far less commonly now than in the past. Because it contains methyltestosterone, an anabolic androgen, this medication is also a federally controlled substance, which can affect how a pharmacy handles and dispenses it.

Cost without insurance, and why comparing pharmacies matters

Prices for esterified estrogens and methyltestosterone vary widely from one pharmacy to the next, so it pays to compare before you fill. There is no manufacturer savings card currently offered for this medication. Enter your ZIP code above to see current prices at pharmacies near you and find the lowest one for your area.

One important wrinkle: the brand Estratest was discontinued by its manufacturer for business reasons unrelated to safety, and product availability in this category has been inconsistent since. Not every pharmacy stocks a version of this product, so it's worth calling ahead or checking availability alongside price.

Alternatives and related hormone therapies

Because the branded Estratest product line has been discontinued and supply of esterified estrogens and methyltestosterone is inconsistent, many patients and prescribers look at estrogen-alone options instead, such as conjugated estrogens (the type of estrogen used in Premarin) or estradiol. If the androgen component was added specifically to address low testosterone symptoms, your provider may also discuss testosterone or methyltestosterone therapy on its own, which as a controlled substance requires its own prescribing considerations.

Some pharmacies carry generic-labeled "esterified estrogens and methyltestosterone" products, but several of these are marketed without FDA-approved labeling rather than as approved, substitutable generics of the original branded drug — ask your pharmacist to confirm exactly what product they're dispensing and whether it's appropriate for you.

Safety information

This medicine carries an FDA boxed warning for its estrogen component: an increased risk of endometrial cancer, breast cancer, cardiovascular events (heart attack, stroke, blood clots in the legs or lungs), and probable dementia in postmenopausal women, particularly with long-term use or when combined with a progestin. It's meant to be used at the lowest effective dose for the shortest time needed.

The methyltestosterone component adds its own risks, including virilization (voice changes, unwanted hair growth, acne, clitoral enlargement — some of which may not reverse), liver toxicity, and unfavorable changes to cholesterol levels. As an anabolic androgen, methyltestosterone is also a federally controlled substance with its own potential for misuse. It should not be used during pregnancy, with undiagnosed abnormal vaginal bleeding, current or past breast cancer, a history of blood clots, stroke, or heart attack, or liver disease.

This is general information, not medical advice — talk with your doctor or pharmacist about whether this medication, or an alternative, is right for you.