Hydrocort-Pramoxine (Perianal) Coupons & Prices

Looking for a hydrocort-pramoxine cream coupon before you check out at the pharmacy counter? This combination of hydrocortisone (an anti-inflammatory corticosteroid) and pramoxine (a local anesthetic) is sold as an affordable generic, but the price for the same tube can still swing noticeably from one pharmacy to the next — so it's worth comparing before you fill. Rx.com checks pricing across 60,000+ U.S. pharmacies so you can see today's price at nearby locations and enter your ZIP above to compare.

What Is Hydrocortisone-Pramoxine Cream and How Does It Work?

Hydrocortisone acetate 2.5% / pramoxine hydrochloride 1% cream is a topical combination used for the relief of inflammation and itching associated with corticosteroid-responsive conditions of the anal region. Hydrocortisone is a corticosteroid that reduces inflammation and itching, while pramoxine is a local anesthetic that provides temporary numbing relief from pain and itch. It's typically applied as a thin film to the affected area three to four times a day; for perianal use, a small amount is usually placed on tissue or a pad and applied externally rather than inserted into the rectum.

Comparing Prices: Why the Pharmacy You Choose Still Matters

A generic-available combination like this one is usually a lower-cost option compared to brand-name anorectal products, but "generic" does not mean the price is the same everywhere — cash prices for identical generic tubes can vary widely between pharmacies in the same city. Because this is an external topical product typically used short-term, it's worth checking a few pharmacies rather than assuming your regular pharmacy has the best price. Enter your ZIP above to compare prices across pharmacies near you and see what a coupon could bring your price down to at checkout.

Brand Names and Related Alternatives

This cream is the generic form of combination products marketed under brand names including Analpram HC and Pramosone. A related product, Proctofoam HC, delivers the same two active ingredients (hydrocortisone and pramoxine) but as a 1%/1% foam rather than a 2.5%/1% cream — ask your pharmacist or provider whether a cream or foam form fits your situation better, since the strengths and vehicle differ. The two active ingredients are also available on their own: hydrocortisone alone, and pramoxine alone, which some patients use in combination or as alternatives depending on what a provider recommends. You can also compare against other hemorrhoidal cream options if you're specifically treating hemorrhoid symptoms.

Safety Information

This product is for external and perianal use only — avoid getting it in your eyes, and it is not an ophthalmic product. Stop using it and contact your doctor if you notice irritation, burning, or symptoms that get worse instead of better. It's meant for short-term use; using topical corticosteroids for a prolonged period, over large areas, on broken skin, or under an occlusive dressing can lead to skin thinning or, rarely, absorption into the body that affects the adrenal glands. Some formulations contain sulfites, which can rarely cause allergic reactions in sensitive individuals. This information is educational and not a substitute for medical advice — talk to your doctor or pharmacist about whether this product is right for you and how long to use it.