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Miebo Bottle — prescription drug image

Miebo

Miebo 3ML of 1.338GM/ML

What is Miebo?

Miebo is an oral medication primarily utilized for the treatment of moderate to severe rheumatoid arthritis. It operates by targeting specific pathways involved in inflammatory processes, thereby reducing pain, swelling, and joint damage associated with the disease. Its use is generally recommended for patients who have not responded adequately to conventional treatments.

Prescription savings · · · ·

What is Miebo ?

Miebo is an oral medication primarily utilized for the treatment of moderate to severe rheumatoid arthritis. It operates by targeting specific pathways involved in inflammatory processes, thereby reducing pain, swelling, and joint damage associated with the disease. Its use is generally recommended for patients who have not responded adequately to conventional treatments.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision, eye redness
  • Tell your doctor if you are pregnant or breastfeeding.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is Miebo used for?
Miebo is FDA-approved to treat the signs and symptoms of dry eye disease. It works by forming a layer over the tear film that reduces tear evaporation, which is one of the underlying causes of dry eye.
How is Miebo different from other dry eye drops like Restasis or Xiidra?
Restasis and Xiidra work by reducing inflammation associated with dry eye, while Miebo takes a different approach: it forms a protective monolayer over the tear film to slow tear evaporation. Because the mechanisms differ, your eye doctor may recommend one, or in some cases a combination, based on the underlying cause of your dry eye.
Can you wear contact lenses with Miebo?
Miebo should not be administered while wearing contact lenses. Remove your contacts before using the drops and wait at least 30 minutes before putting them back in.
How much does Miebo cost without insurance?
Pharmacy cash prices for Miebo vary by location and pharmacy. Enter your ZIP code on Rx.com to compare current prices near you, and check whether the manufacturer's savings card program (terms vary, generally for commercially insured patients) applies to your situation.
Is there a generic version of Miebo?
No. Miebo (perfluorohexyloctane ophthalmic solution) does not currently have an FDA-approved generic equivalent available.
How much does Miebo cost without insurance?
The price of Miebo without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Miebo?
Common side effects of Miebo may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Blurred vision, eye redness. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Miebo?
Generic versions may be available for Miebo. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Miebo on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Miebo?
The cheapest pharmacy for Miebo depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Miebo near you.

Miebo Coupons & Prices

Miebo 3ML of 1.338GM/ML

Miebo Bottle — prescription drug image
Prescription
Miebo 3ml of 1.338gm/ml (1)
your area ·

Looking for a Miebo coupon? Miebo (perfluorohexyloctane ophthalmic solution) is the first and only FDA-approved dry eye treatment that works by forming a protective layer over the tear film to reduce tear evaporation, and Rx.com can help you find the lowest cash price near you alongside the manufacturer's savings program details below.

What Is Miebo and How Does It Work?

Miebo is a brand-name prescription eye drop containing perfluorohexyloctane, a water- and preservative-free semifluorinated alkane. It's FDA-approved to treat the signs and symptoms of dry eye disease (DED). Rather than adding moisture the way traditional artificial tears do, Miebo forms a stable monolayer over the surface of the tear film that slows tear evaporation, addressing one of the underlying causes of dry eye. The typical dose is one drop in each affected eye four times a day.

Manufacturer Savings Card vs. the Rx.com Cash Coupon

Miebo's manufacturer offers an official savings card program through its own site; terms, eligibility, and how much it reduces your cost can vary and typically apply only to patients with commercial (private) insurance. If you're uninsured, on Medicare, or the manufacturer card is declined at the pharmacy counter, the Rx.com cash coupon can still be used to shop the price at pharmacies in your area. There is currently no generic version of Miebo, so comparing pharmacy cash prices and checking whether you qualify for the manufacturer's program are the two main ways to manage cost. Enter your ZIP above to see today's price at pharmacies near you.

How Miebo Compares to Other Dry Eye Drops

Miebo works differently than several other prescription dry eye options. Restasis and Cequa are both cyclosporine-based anti-inflammatory drops (cyclosporine is also available as a standalone generic ophthalmic solution), and Xiidra (lifitegrast) targets inflammation through a different mechanism. Miebo instead targets tear evaporation directly by coating the tear film, rather than reducing inflammation. Your eye doctor can help determine which mechanism fits your specific type of dry eye, and some patients use more than one approach together.

Safety Information

Miebo should not be used by anyone with a known hypersensitivity to perfluorohexyloctane. It should not be used while wearing contact lenses — remove lenses before applying a dose and wait at least 30 minutes before putting them back in. The most commonly reported side effect is temporary blurred vision right after the drop is instilled, occurring in less than 4% of patients in studies. Miebo does not carry a boxed warning. This information is educational and not a substitute for medical advice; talk with your eye doctor about whether Miebo is right for you.

Sources & accuracy

This Miebo information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Miebo on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.