Nexletol
Nexletol 30 Tablets
What is Nexletol?
Nexletol is a medication that helps lower cholesterol levels in the body. It is used to reduce the risk of heart attacks and strokes by preventing cholesterol buildup in blood vessels.Side Effects
- Hearing or feeling a snap or pop, bruising right after an injury, or unable to move or put weight in an affected tendon area, including the shoulder, upper arm, or back of the ankle
- Joint pain, stiffness, or swelling, lower back, side, or stomach pain, swelling of the feet or lower legs
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Warnings
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart problems (including heart attack), stroke, gout, muscle problems, or a history of tendon problems.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- This medicine may cause the following problems:Increased uric acid levels in the blood, which can lead to goutTendon problems, including swelling, inflammation, or ruptureIncreased risk for muscle pain or weakness, especially when taken together with simvastatin or pravastatin
Prescription savings · · · ·
What is Nexletol ?
Nexletol is a medication that helps lower cholesterol levels in the body. It is used to reduce the risk of heart attacks and strokes by preventing cholesterol buildup in blood vessels.- Hearing or feeling a snap or pop, bruising right after an injury, or unable to move or put weight in an affected tendon area, including the shoulder, upper arm, or back of the ankle
- Joint pain, stiffness, or swelling, lower back, side, or stomach pain, swelling of the feet or lower legs
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Muscle pain or weakness
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart problems (including heart attack), stroke, gout, muscle problems, or a history of tendon problems.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- This medicine may cause the following problems:Increased uric acid levels in the blood, which can lead to goutTendon problems, including swelling, inflammation, or ruptureIncreased risk for muscle pain or weakness, especially when taken together with simvastatin or pravastatin
Nexletol Coupons & Prices
Nexletol 30 Tablets
Looking for a Nexletol coupon? Nexletol (bempedoic acid) is a brand-name, non-statin LDL-cholesterol-lowering medicine with no generic version yet, so pharmacy prices can vary widely from store to store — enter your ZIP above to see today's price near you, and see below how the manufacturer's savings card compares to the Rx.com cash coupon.
What Is Nexletol and How Does It Work?
Nexletol is the brand name for bempedoic acid, an ATP citrate lyase (ACL) inhibitor — a type of non-statin medicine that lowers LDL cholesterol through a different pathway in the liver than statins use. It's FDA-approved to reduce the risk of major cardiovascular events (such as heart attack, stroke, or the need for a coronary procedure) in adults at increased cardiovascular risk who aren't able to take a fully effective dose of a statin, including those not on a statin at all. It's also approved as an add-on to diet, used alone or together with other LDL-lowering medicines like statins or ezetimibe, to lower LDL-C in adults with primary high cholesterol (including a hereditary form called heterozygous familial hypercholesterolemia) — particularly for patients who can't tolerate an adequate dose of a statin.
There is no generic version of Nexletol currently available, so it's only sold under the brand name.
Nexletol Manufacturer Savings Card vs. the Rx.com Cash Coupon
Nexletol's manufacturer offers an official savings card program (available through the manufacturer's own savings-card website) that can lower out-of-pocket costs for many patients, but like most brand savings cards, it's generally intended for people with commercial (private/employer) insurance — terms, eligibility, and any caps vary and are set by the manufacturer, so check the current details directly with them or your pharmacist.
If you're uninsured, on Medicare or Medicaid, or your savings card is declined at the pharmacy counter, the Rx.com coupon above can still be used for a cash price on Nexletol. A related combination product, Nexlizet (bempedoic acid/ezetimibe), also has its own patient support and savings resources through its manufacturer if your doctor prescribes that version instead.
Nexletol Alternatives and Related Cholesterol Medicines
Nexletol is often used alongside or as an alternative to other cholesterol-lowering options. Common statins like atorvastatin and rosuvastatin are typically tried first for most patients since they have long track records and generic versions. Ezetimibe, another non-statin option, lowers cholesterol absorption in the gut and can be combined with Nexletol (as in the combination product Nexlizet). For patients who need additional LDL lowering or can't take oral therapies, injectable options like Repatha (a PCSK9 inhibitor) are another non-statin class your doctor may consider.
Which option is right for you depends on your cholesterol levels, cardiovascular risk, statin tolerance, and insurance coverage — talk to your prescriber about which combination makes sense.
Nexletol Safety Information
Nexletol does not carry a boxed warning, but it does have some precautions worth knowing. It can raise uric acid levels and trigger gout flares, and it has been associated with tendon rupture or tendon injury — this risk is higher in people over 60, those taking corticosteroids or fluoroquinolone antibiotics, people with kidney failure, or those with a prior tendon disorder. It can also raise liver enzymes, so your doctor may monitor liver function. Nexletol isn't recommended during pregnancy because of how it works, and it shouldn't be used by anyone with a known hypersensitivity reaction (such as anaphylaxis, angioedema, rash, or hives) to it. Muscle-related symptoms such as muscle spasms have been reported in clinical trials, so tell your doctor about all medicines you're taking, including statins, and about any muscle pain or weakness you notice.
This is general information, not medical advice — talk with your doctor or pharmacist about whether Nexletol is right for you and about any symptoms you notice while taking it.
This Nexletol information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Nexletol on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.