Phenobarbital
PHENobarbital 16.2MG
What is Phenobarbital?
Phenobarbital is a prescription medication primarily used to control seizures and manage anxiety. By slowing down brain activity, it helps prevent seizures and promote calmness. Users can find information on cost, savings cards, and mail-order options on Rx.com, where they can also connect with licensed providers for prescriptions online.Side Effects
- Hives or severe skin rash
- Swelling of eyelids or face
- Severe drowsiness, confusion, or slurred speech
Warnings
- Check with your doctor before taking if you are pregnant, breastfeeding, or are planning to become pregnant, or if you have any type of lung disease, asthma, or liver disease.
- If you are using this medicine regularly, do not stop taking it suddenly without first asking your doctor. You may need to take less and less before stopping completely.
- You should not use more of this medicine or take it for longer periods than your doctor has ordered. Phenobarbital can be habit-forming.
- This medicine can make you drowsy. Be careful when driving or operating machinery.
- Uncontrollable eye movements
Prescription savings · · · ·
What is Phenobarbital ?
Phenobarbital is a prescription medication primarily used to control seizures and manage anxiety. By slowing down brain activity, it helps prevent seizures and promote calmness. Users can find information on cost, savings cards, and mail-order options on Rx.com, where they can also connect with licensed providers for prescriptions online.- Hives or severe skin rash
- Swelling of eyelids or face
- Severe drowsiness, confusion, or slurred speech
- Shortness of breath or trouble breathing
- Uncontrollable eye movements
- Hallucinations
- Yellowing of eyes or skin
- Check with your doctor before taking if you are pregnant, breastfeeding, or are planning to become pregnant, or if you have any type of lung disease, asthma, or liver disease.
- If you are using this medicine regularly, do not stop taking it suddenly without first asking your doctor. You may need to take less and less before stopping completely.
- You should not use more of this medicine or take it for longer periods than your doctor has ordered. Phenobarbital can be habit-forming.
- This medicine can make you drowsy. Be careful when driving or operating machinery.
- Uncontrollable eye movements
- Yellowing of eyes or skin
- Hallucinations
Phenobarbital Coupons & Prices
PHENobarbital 16.2MG
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Phenobarbital prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 15mg · Tablet | 60 | — | $21.49 |
| 16.2mg · Tablet | 60 | $30.59 | $26.07 |
| 30mg · Tablet | 60 | $22.79 | $14.90 |
| 32.4mg · Tablet | 60 | $46.59 | $27.33 |
| 60mg · Tablet | 60 | $34.37 | $17.69 |
| 64.8mg · Tablet | 60 | $46.39 | $30.89 |
| 97.2mg · Tablet | 60 | $334.49 | $36.21 |
| 100mg · Tablet | 60 | $35.19 | $23.39 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
Looking for a phenobarbital coupon? Phenobarbital is a long-established generic barbiturate, but the price you're quoted for it can still swing a lot from one pharmacy to the next — which is exactly where comparing matters. Rx.com checks pricing across 60,000+ pharmacies so you can enter your ZIP above and see today's price near you before you fill.
What is phenobarbital and how does it work?
Phenobarbital is a barbiturate that works as an anticonvulsant and sedative-hypnotic. It's FDA-approved to help control generalized tonic-clonic (grand mal) and partial seizures, and for emergency control of certain acute convulsive episodes, such as those associated with status epilepticus, eclampsia, meningitis, tetanus, or toxic reactions to strychnine or local anesthetics. It's also FDA-labeled as a sedative for daytime sedation and as part of pre-anesthetic sedation. Outside of its approved uses, clinicians also use phenobarbital for neonatal seizures and in phenobarbital-based protocols for alcohol or benzodiazepine withdrawal.
There is no widely marketed brand-name version of oral or standard injectable phenobarbital in the US today — it's essentially a generic-only medication. (An older brand, Luminal, is discontinued. A separate, newer branded IV product called SEZABY, formulated specifically for neonatal seizures, is a distinct product from the generic form most people are prescribed.)
Phenobarbital cost without insurance
Phenobarbital is generic, and generic status alone doesn't guarantee a consistent price — cash prices for the same generic drug can differ substantially depending on which pharmacy fills it, even within the same city. That's true for phenobarbital too, so it's worth comparing before you pick a pharmacy rather than assuming your usual one has the best price.
There is currently no manufacturer savings card for phenobarbital. Enter your ZIP code above to compare prices at pharmacies near you and see today's price.
Phenobarbital vs. other seizure and sedative medications
Phenobarbital is one of several medications used to manage seizures. Other commonly prescribed anticonvulsants include levetiracetam, phenytoin, and gabapentin, each with its own dosing profile and side-effect considerations. Benzodiazepines such as clonazepam, diazepam, and lorazepam are also used for seizure-related and sedation purposes in some situations. Which medication is right depends on the type of seizures or condition being treated, and switching between these classes should only be done with a prescriber's guidance — they are not interchangeable.
Phenobarbital safety information
Phenobarbital is a Schedule IV controlled substance. Taking it together with opioids or other central nervous system depressants can cause profound sedation, slowed or stopped breathing, coma, or death. With continued use, the body can become physically dependent, and stopping abruptly can trigger a serious, potentially life-threatening withdrawal, including seizures — phenobarbital should only be tapered off under a doctor's supervision, never stopped suddenly on your own. It is habit-forming with a potential for misuse, may cause serious harm to a fetus if used during pregnancy, and can rarely cause severe skin reactions such as Stevens-Johnson syndrome. It should be used cautiously in people with breathing problems, liver impairment, or in older or debilitated patients.
This is general information, not medical advice — talk with your doctor or pharmacist about whether phenobarbital is right for you and how to take it safely.
This Phenobarbital information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Phenobarbital on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.