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Povidone-Iodine Bottle — prescription drug image

Povidone-Iodine

Povidone-Iodine 236ML of 10%

What is Povidone-Iodine?

Povidone-iodine is an antiseptic used for skin disinfection before and after surgery. It also treats infections in wounds. Being a broad-spectrum antiseptic, it effectively kills bacteria, fungi, viruses, and protozoa on the skin's surface, reducing the risk of infection.

Prescription savings · · · ·

What is Povidone-Iodine ?

Povidone-iodine is an antiseptic used for skin disinfection before and after surgery. It also treats infections in wounds. Being a broad-spectrum antiseptic, it effectively kills bacteria, fungi, viruses, and protozoa on the skin's surface, reducing the risk of infection.
  • Cramps, vomiting, or loss of appetite.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Anxiety, nervousness, or agitation.
  • Muscle spasms, or seizures.
  • Make sure your doctor knows if you are pregnant or breast feeding. Tell your doctor if you have had a reaction to a topical antibacterial cleanser in the past.
  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
  • Cramps, vomiting, or loss of appetite.
  • Muscle spasms, or seizures.
What is povidone-iodine (Betadine) used for?
Povidone-iodine is an over-the-counter antiseptic used as first aid to help prevent infection in minor cuts, scrapes, and burns, and as a skin prep before injections or surgical procedures. Some povidone-iodine products are also formulated as a vaginal antiseptic. It's for topical use only and is not a treatment for systemic infections.
Is povidone-iodine the same as iodine?
Not exactly. Povidone-iodine is a compound that combines elemental iodine with povidone, a carrier that allows the iodine to be released slowly on the skin. This makes it gentler and longer-acting than tincture of iodine alone, though both are iodine-based antiseptics.
Can you put povidone-iodine on an open wound?
It's commonly used on minor cuts and scrapes as first aid, but you should avoid using it on deep puncture wounds, animal bites, or serious burns without checking with a healthcare provider first. If irritation or a rash develops, stop use and talk to your provider.
Is povidone-iodine safe during pregnancy?
Talk to your healthcare provider before using povidone-iodine during pregnancy or while breastfeeding, especially for prolonged use or over a large area of skin. Because iodine can be absorbed through skin and mucous membranes and may affect thyroid function, your provider can advise on whether and how to use it safely in your situation.
How do you dilute Betadine for wound cleaning?
Dilution instructions vary by product and intended use, so follow the specific directions on your product's label or the guidance given by your healthcare provider. Do not guess at a dilution — using it incorrectly could reduce its effectiveness or increase skin irritation.
How much does Povidone-Iodine cost without insurance?
The price of Povidone-Iodine without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Povidone-Iodine?
Common side effects of Povidone-Iodine may include: Cramps, vomiting, or loss of appetite., Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Anxiety, nervousness, or agitation., Muscle spasms, or seizures.. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Povidone-Iodine?
Generic versions may be available for Povidone-Iodine. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Povidone-Iodine on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Povidone-Iodine?
The cheapest pharmacy for Povidone-Iodine depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Povidone-Iodine near you.

Povidone-Iodine Coupons & Prices

Povidone-Iodine 236ML of 10%

Povidone-Iodine Bottle — prescription drug image
Prescription
Povidone-Iodine 236ml of 10% (0.5)
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Povidone-iodine (sold under brand names like Betadine) is an over-the-counter topical antiseptic used to help prevent infection in minor cuts, scrapes, and burns, and as a skin prep before injections or procedures; it's available without a prescription, and a povidone-iodine coupon from Rx.com can help you compare pharmacy prices before you buy, since some OTC antiseptics still cost less with a coupon or store discount depending on the pharmacy — enter your ZIP above to see today's price.

What Is Povidone-Iodine and How Does It Work?

Povidone-iodine is an iodophor, meaning it combines iodine with a carrier (povidone) that releases the antiseptic slowly on skin and mucous membranes. It's classified under the FDA's OTC "first aid antiseptic" monograph and works by killing a broad range of bacteria, fungi, and viruses on contact with skin. You'll find it as a liquid solution, ointment, prep pads/swabs, and surgical scrub, sold under brand names such as Betadine, Betadine Surgical Scrub, Povidone Iodine Prep Pads, and Operand, as well as store-brand generics.

Common uses include cleaning minor cuts, scrapes, and burns before covering them, prepping skin before an injection, and use as a surgical hand or skin scrub. Some povidone-iodine products are also formulated for use as a vaginal antiseptic; these are a different product from the wound-care solutions above, so check the label before use. It is for external, topical use only — it is not effective against COVID-19 or other infections that require systemic (internal) treatment.

How to Use Povidone-Iodine Safely

  • Apply to clean, unbroken or minor-injury skin only, following the product label's directions.
  • Do not use in the eyes, and avoid using it on deep puncture wounds, animal bites, or serious burns without talking to a healthcare provider first.
  • Stop use and check with your provider if a rash, irritation, or other reaction develops.
  • Talk to your provider before prolonged or large-surface-area use, since iodine can be absorbed through the skin and affect thyroid function — this is a particular concern for newborns, and for pregnant or breastfeeding women.

This is general information, not medical advice — check with your pharmacist or provider about the right way to use povidone-iodine for your specific situation.

Saving on Povidone-Iodine

Povidone-iodine is sold over the counter and generic versions are widely available alongside name brands like Betadine. Because it's OTC, you generally won't need a prescription-style manufacturer copay card here — instead, the best way to save is to compare what different pharmacies charge for the same product and size, since OTC antiseptic pricing can vary by retailer. Enter your ZIP code above to compare prices at pharmacies near you before you buy.

Povidone-Iodine vs. Other Antiseptics

Povidone-iodine isn't the only option for cleaning minor wounds. Hydrogen peroxide is another OTC antiseptic, though it's generally used differently and can be harsher on healing tissue with repeated use. Chlorhexidine is another antiseptic used for skin prep and scrubs. For infection prevention after a wound is cleaned, some people use a topical antibiotic ointment such as bacitracin or a combination product like neomycin/polymyxin/bacitracin; for burn care specifically, silver sulfadiazine is a prescription option your provider may recommend. Ask your pharmacist which antiseptic best fits your specific wound or use case.

Sources & accuracy

This Povidone-Iodine information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Povidone-Iodine on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.